JPH06500636A - 化学、生化学および生物学的な測定試料の特異物質を選択的に検出する光学的な方法 - Google Patents

化学、生化学および生物学的な測定試料の特異物質を選択的に検出する光学的な方法

Info

Publication number
JPH06500636A
JPH06500636A JP4511206A JP51120692A JPH06500636A JP H06500636 A JPH06500636 A JP H06500636A JP 4511206 A JP4511206 A JP 4511206A JP 51120692 A JP51120692 A JP 51120692A JP H06500636 A JPH06500636 A JP H06500636A
Authority
JP
Japan
Prior art keywords
sensitive
waveguide
diffraction grating
chemical
grating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4511206A
Other languages
English (en)
Japanese (ja)
Inventor
ティーフェンターラー・クルト
ブリゲ・ベロニク
Original Assignee
アルティフィシアル・ゼンジング・インストルメンツ・アーエスイー・アクチェンゲゼルシャフト
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アルティフィシアル・ゼンジング・インストルメンツ・アーエスイー・アクチェンゲゼルシャフト filed Critical アルティフィシアル・ゼンジング・インストルメンツ・アーエスイー・アクチェンゲゼルシャフト
Publication of JPH06500636A publication Critical patent/JPH06500636A/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
    • G01N21/7703—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides
    • G01N21/774—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure
    • G01N21/7743—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator using reagent-clad optical fibres or optical waveguides the reagent being on a grating or periodic structure the reagent-coated grating coupling light in or out of the waveguide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/01—Arrangements or apparatus for facilitating the optical investigation
    • G01N21/03—Cuvette constructions
    • G01N2021/0385—Diffusing membrane; Semipermeable membrane

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plasma & Fusion (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP4511206A 1991-07-02 1992-06-19 化学、生化学および生物学的な測定試料の特異物質を選択的に検出する光学的な方法 Pending JPH06500636A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1954/91-1 1991-07-02
CH1954/91A CH681920A5 (de) 1991-07-02 1991-07-02

Publications (1)

Publication Number Publication Date
JPH06500636A true JPH06500636A (ja) 1994-01-20

Family

ID=4222477

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4511206A Pending JPH06500636A (ja) 1991-07-02 1992-06-19 化学、生化学および生物学的な測定試料の特異物質を選択的に検出する光学的な方法

Country Status (4)

Country Link
EP (1) EP0551456A1 (de)
JP (1) JPH06500636A (de)
CH (1) CH681920A5 (de)
WO (1) WO1993001487A1 (de)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012058218A (ja) * 2010-09-13 2012-03-22 Shimadzu Corp 導波モード共鳴格子を用いた屈折率測定装置及び屈折率測定方法
JP2016524163A (ja) * 2013-07-12 2016-08-12 エフ．ホフマン−ラ ロッシュ アーゲー 結合親和性の検出に用いる装置

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0617273B1 (de) * 1993-03-26 2002-10-16 F. Hoffmann-La Roche Ag Optisches Verfahren und Vorrichtung zur Analyse von Substanzen an Sensoroberflächen
GB9314991D0 (en) * 1993-07-20 1993-09-01 Sandoz Ltd Mechanical device
DE4345225A1 (de) * 1993-11-15 1995-05-18 Hoffmann La Roche Anordnung zur Analyse von Substanzen an der Oberfläche eines optischen Sensors
EP0679250B1 (de) * 1993-11-15 2000-03-15 CARL ZEISS JENA GmbH Anordnung zur analyse von substanzen an der oberfläche eines optischen sensors
DE4424628B4 (de) * 1994-07-13 2005-11-17 Lau, Matthias, Dipl.-Ing. Verfahren und Anordnung zur Brechzahlmessung verschiedener Medien
GB9602542D0 (en) * 1996-02-08 1996-04-10 Fisons Plc Analytical device
EP0890095B1 (de) 1996-03-30 2007-11-21 Novartis AG Integriert optischer lumineszenzsensor
DE19615366B4 (de) * 1996-04-19 2006-02-09 Carl Zeiss Jena Gmbh Verfahren und Einrichtung zum Nachweis physikalischer, chemischer, biologischer oder biochemischer Reaktionen und Wechselwirkungen
KR20000048736A (ko) 1996-09-30 2000-07-25 아벤티스 레제아르히 운트 테히놀로기스 게엠베하 운트 콤파니 카게 수중에 용해되어 있거나 분산되어 있는 화학 물질을 검출하기 위한 광학 센서
US8111401B2 (en) * 1999-11-05 2012-02-07 Robert Magnusson Guided-mode resonance sensors employing angular, spectral, modal, and polarization diversity for high-precision sensing in compact formats
US7046357B2 (en) 2003-01-30 2006-05-16 Ciphergen Biosystems, Inc. Apparatus for microfluidic processing and reading of biochip arrays

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3680999D1 (de) * 1985-05-29 1991-09-26 Artificial Sensing Instr Asi A Optischer sensor zum selektiven nachweis von substanzen und zum nachweis von brechzahlaenderungen in messubstanzen.
DE3723159A1 (de) * 1986-07-17 1988-01-21 Prosumus Ag Chemosensor sowie mit diesem durchfuehrbare verfahren
US5082629A (en) * 1989-12-29 1992-01-21 The Board Of The University Of Washington Thin-film spectroscopic sensor
EP0455067B1 (de) * 1990-05-03 2003-02-26 F. Hoffmann-La Roche Ag Mikrooptischer Sensor
DE4033912C2 (de) * 1990-10-25 1995-05-24 Fraunhofer Ges Forschung Optischer Sensor

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012058218A (ja) * 2010-09-13 2012-03-22 Shimadzu Corp 導波モード共鳴格子を用いた屈折率測定装置及び屈折率測定方法
JP2016524163A (ja) * 2013-07-12 2016-08-12 エフ．ホフマン−ラ ロッシュ アーゲー 結合親和性の検出に用いる装置

Also Published As

Publication number Publication date
EP0551456A1 (de) 1993-07-21
WO1993001487A1 (de) 1993-01-21
CH681920A5 (de) 1993-06-15

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