JPH06181979A - Tube for applying tissue adhesive - Google Patents

Abstract

PURPOSE:To provide a tube for applying a tissue adhesive, having the capability of equally and evenly applying the agent to the wound of the tissue. CONSTITUTION:A tube body 10 with two liquid flow passages 11 and 12 allowing the separate charge of two types of liquid coagulating upon mixing, and at least one gas flow passage 13 allowing the feed of the pressurized air is provided, and the base ends of the two liquid flow passages are respectively fitted with syringe connection members 14 and 15. In addition, an air source connection member 16 is fitted to the base end of the gas flow passage 13.

Description

Detailed Description of the Invention

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention applies an adhesive agent for a living tissue used for adhering a wound of a tissue, which is inserted into a deep lumen tissue of a living body such as stomach, intestine or bronchus using an endoscope. Tube for use.

[0002]

2. Description of the Related Art Conventionally, as a tube for applying a biological tissue adhesive of this type, two liquid flow paths are provided so as to extend vertically through the tube body, and syringe connecting members are respectively provided on the proximal ends of the two liquid flow paths. The one with was known. This tube contains two components that clot when mixed (eg, XII.
A solution containing factor I and fibrinogen and a solution containing thrombin) are injected into a wound of living tissue without being mixed with each other, and the mixture is applied while being mixed at the wound site without surgery. It is extremely effective in treating deep luminal tissues of the living body.

[0003]

However, the above two liquids have peculiar viscosities, and even if they are pressure-fed using a syringe, they are ejected in a rod shape from the tip ejection port of the tube main body, or become a curtain like a gradual curtain. It was merely extruded, and the liquid did not reach depending on the position of the wound of the living tissue, which made it difficult to apply, and it was difficult to evenly and uniformly apply the wound.

Further, in the case where the work is temporarily stopped and the work is restarted after a short time during the coating work on the wound, the liquid remaining in the ejection port at the time of the first coating is coagulated before the work is restarted. There is a possibility that the ejection port may be blocked, and subsequent coating may not be possible.

An object of the present invention is to solve such a problem, and not only to enable the application of the wound of living tissue at any position, but also to apply it uniformly to the wound. In addition, since the liquid is blown off by the gas, part of the liquid does not remain at the liquid ejection port, so it is possible to stop it once during the coating work and restart the work after a while. Another object of the present invention is to provide a novel tube for applying a biological tissue adhesive.

[0006]

In order to achieve this object, the present invention provides two liquid flow passages and at least one gas flow passage so as to extend vertically through the tube body. A tube for applying a biological tissue adhesive, characterized in that a syringe connecting member is provided on each of the proximal ends and an air source connecting member is provided on each of the proximal ends of a gas flow path.

[0007]

According to the present invention, the tube body is inserted from the distal end toward the wound of the deep lumen tissue of the living body such as the stomach, intestine or bronchus while using the endoscope. And, an air source connecting member provided on the base end side of at least one gas flow path,
Each syringe is connected to an air source, and each syringe that has taken two components that coagulate when mixed is connected to a syringe connecting member. Thereafter, both liquids are injected from both syringes toward the wound of the luminal tissue, and at the same time, the air source is opened to blow air. When the air is ejected from the ejection port, it is sprayed in a diffusive state, so that the above two solutions having a certain degree of viscosity are also entrained therein. Therefore, the two liquids are blown in a diffused manner up to the wound while mixing on air, and are evenly and uniformly attached to the wound.

Further, both liquids that are entrained in the air and ejected together with the air do not remain in the ejection port even if the ejection is stopped once during the ejection, so both liquids are mixed near the ejection port. It is possible to resume the application without clotting.

[0009]

DESCRIPTION OF THE PREFERRED EMBODIMENTS Next, an embodiment according to the present invention will be described with reference to the drawings. 1 is a configuration diagram of a tube for applying a biological tissue adhesive according to an embodiment of the present invention, FIG. 2 is an enlarged cross-sectional view of a tube body, and FIG. 3 is a distal end portion of the tube body showing a liquid / gas spray state. FIG.

The tube body 10 shown in FIGS. 1 to 3 has two liquid channels 11 and 12 and one gas channel 13. The tube body 10 is made of a resin material having bending strength such as polyvinyl chloride, polypropylene and polyethylene. In this case, as shown in FIG. 2, it is manufactured by an extrusion molding method as having two holes for a liquid flow path and one hole for a gas flow path in a cross section. It goes without saying that the single tube unit and the single gas channel tube unit may be manufactured so as to be integrated.

The outer diameter of the tube body 10 is preferably about 5 mm, and in the case where a total of three liquid flow paths 11 and 12 and one gas flow path 13 in the cross section are provided, the inner diameter of each of them is 0. It is preferably about 7 mm. However, it is not limited to this value. The liquid channels 11 and 12 need to have the same diameter in order to inject the two liquids in the same amount, but the gas channel does not necessarily have to have the same diameter as the liquid channel.

Syringe connecting members 14 and 15 are provided on the proximal ends of the liquid flow paths 11 and 12, respectively. The syringe connecting members 14 and 15 can be directly connected to the tapered connecting end St provided on the end surface of the syringe S. In addition, an air source connecting member 16 is provided on the base end side of the gas flow path 13 to which the output tube end At extending from the air source A can be directly connected.

Next, the specific operation of the living tissue adhesive application tube according to this embodiment will be described. First, the tube body 10 is inserted toward the wound of a deep lumen tissue of a living body such as the stomach, intestine or bronchus using an endoscope. Then, the terminal of the air output tube extending from the air source A is connected to the air source connecting member 16 provided on the base end side of the gas flow path 13. Then, the two components (for example, the first solution containing the above-mentioned factor XIII and fibrinogen and the second solution containing thrombin) which coagulate when mixed are taken into each syringe S, and the syringe S is tapered. Connection members 14 and 15 provided on the base end sides of the two liquid flow paths via the cylindrical connection end St, respectively.
Connect to.

When the preparatory work is completed in this way, while looking through the endoscope, both syringes are operated in parallel to separately inject both liquids through the liquid flow paths 11 and 12, and at the same time, the valve Av of the air source A is turned on. It is opened and pressurized air is injected through the gas flow path 13. As a result, air is sprayed in a diffusive form from the air ejection port at the tip of the tube body 10, and the two liquids are blown off by being trapped therein. Therefore, both liquids are mixed and sprayed evenly to the wound of the living tissue H as shown in FIG. 3, and are evenly and uniformly applied to the wound.

Further, both liquids that are entrained in the air and ejected do not remain at the ejection port because they are blown by the air even if the coating is temporarily stopped during the ejection. Therefore,
Both liquids do not mix and coagulate in the vicinity of the jet outlet while the coating operation is stopped, and the jet outlet is not blocked, so that the coating operation can be continued thereafter.

In this embodiment, two liquid flow paths,
The case where a total of three flow paths are provided with one gas flow path has been described, but the present invention is not limited to this, and a total of four flow paths may be provided for each of the liquid flow path and the gas flow path. May be more than that.

[0017]

As described above, the living tissue adhesive application tube according to the present invention is provided with a tube body having two liquid flow paths and at least one gas flow path.
Since the syringe connection member is provided on each of the proximal ends of the two liquid flow paths, and the air source connection member is provided on each of the proximal ends of the gas flow paths, two liquids that coagulate when mixed are stored in the deep lumen tissue of the living body. It is possible to separately inject it toward the wound and to spray both of these liquids in a spray form evenly and evenly on the wound. Moreover, since both liquids that are jetted while being entrained in the air do not remain at the jet outlet, they exhibit various excellent effects such as being interrupted in the middle of coating and allowing the coating to be resumed without any trouble after a short time.

[Brief description of drawings]

FIG. 1 is a configuration diagram of a living tissue adhesive application tube according to an embodiment of the present invention.

FIG. 2 is an enlarged sectional view of a tube body.

FIG. 3 is an enlarged cross-sectional view of the tip portion of the tube body showing a liquid / gas spray state.

[Explanation of symbols]

 10 Tube Body 11 Liquid Flow Path 12 Liquid Flow Path 13 Gas Flow Path 14 Syringe Connection Member 15 Syringe Connection Member 16 Air Source Connection Member S Syringe St Connection Terminal A Air Source At Output Tube End Av Valve H Living Tissue

Claims (1)

[Claims] 1. A liquid flow path and at least one gas flow path are provided so as to extend longitudinally through a tube body, and a syringe connecting member is provided on the proximal end side of the liquid flow path, and A tube for applying a biological tissue adhesive, comprising an air source connecting member on the base end side.