JPH0563446B2 - - Google Patents
Info
- Publication number
- JPH0563446B2 JPH0563446B2 JP20111186A JP20111186A JPH0563446B2 JP H0563446 B2 JPH0563446 B2 JP H0563446B2 JP 20111186 A JP20111186 A JP 20111186A JP 20111186 A JP20111186 A JP 20111186A JP H0563446 B2 JPH0563446 B2 JP H0563446B2
- Authority
- JP
- Japan
- Prior art keywords
- chlorhexidine gluconate
- emollient
- ethanol
- composition
- disinfectant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 52
- 239000003974 emollient agent Substances 0.000 claims description 42
- YZIYKJHYYHPJIB-UUPCJSQJSA-N chlorhexidine gluconate Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O.C1=CC(Cl)=CC=C1NC(=N)NC(=N)NCCCCCCNC(=N)NC(=N)NC1=CC=C(Cl)C=C1 YZIYKJHYYHPJIB-UUPCJSQJSA-N 0.000 claims description 37
- 229960003333 chlorhexidine gluconate Drugs 0.000 claims description 37
- 239000000203 mixture Substances 0.000 claims description 28
- 239000000645 desinfectant Substances 0.000 claims description 24
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 11
- 239000000194 fatty acid Substances 0.000 claims description 11
- 229930195729 fatty acid Natural products 0.000 claims description 11
- 150000004665 fatty acids Chemical class 0.000 claims description 11
- HBTAOSGHCXUEKI-UHFFFAOYSA-N 4-chloro-n,n-dimethyl-3-nitrobenzenesulfonamide Chemical group CN(C)S(=O)(=O)C1=CC=C(Cl)C([N+]([O-])=O)=C1 HBTAOSGHCXUEKI-UHFFFAOYSA-N 0.000 claims description 10
- 229940031578 diisopropyl adipate Drugs 0.000 claims description 9
- -1 polyoxyethylene Polymers 0.000 claims description 8
- 238000004659 sterilization and disinfection Methods 0.000 claims description 8
- 229920003171 Poly (ethylene oxide) Polymers 0.000 claims description 7
- 125000003976 glyceryl group Chemical group [H]C([*])([H])C(O[H])([H])C(O[H])([H])[H] 0.000 claims description 7
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
- 235000011187 glycerol Nutrition 0.000 claims description 4
- 150000002314 glycerols Chemical class 0.000 claims description 3
- RDOFJDLLWVCMRU-UHFFFAOYSA-N Diisobutyl adipate Chemical compound CC(C)COC(=O)CCCCC(=O)OCC(C)C RDOFJDLLWVCMRU-UHFFFAOYSA-N 0.000 claims description 2
- IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical class C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 claims description 2
- 229940031769 diisobutyl adipate Drugs 0.000 claims description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 25
- 241000894006 Bacteria Species 0.000 description 22
- 239000000243 solution Substances 0.000 description 13
- 230000000249 desinfective effect Effects 0.000 description 10
- 239000012488 sample solution Substances 0.000 description 10
- 239000007864 aqueous solution Substances 0.000 description 9
- 238000011084 recovery Methods 0.000 description 8
- 238000001035 drying Methods 0.000 description 7
- 230000000694 effects Effects 0.000 description 6
- 241000191967 Staphylococcus aureus Species 0.000 description 5
- 238000002474 experimental method Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 239000011521 glass Substances 0.000 description 4
- 210000002966 serum Anatomy 0.000 description 4
- 230000037380 skin damage Effects 0.000 description 4
- 206010013786 Dry skin Diseases 0.000 description 3
- 238000000540 analysis of variance Methods 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid ester group Chemical group C(CCCCCCCCCCC)(=O)O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000001954 sterilising effect Effects 0.000 description 3
- 238000001356 surgical procedure Methods 0.000 description 3
- HSFWRNGVRCDJHI-UHFFFAOYSA-N Acetylene Chemical compound C#C HSFWRNGVRCDJHI-UHFFFAOYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 2
- 230000007423 decrease Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 239000002736 nonionic surfactant Substances 0.000 description 2
- 208000017520 skin disease Diseases 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical compound C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 235000019733 Fish meal Nutrition 0.000 description 1
- 102000011782 Keratins Human genes 0.000 description 1
- 108010076876 Keratins Proteins 0.000 description 1
- 239000005639 Lauric acid Substances 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 241000607720 Serratia Species 0.000 description 1
- 241000607715 Serratia marcescens Species 0.000 description 1
- 206010040880 Skin irritation Diseases 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 239000012888 bovine serum Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 210000002421 cell wall Anatomy 0.000 description 1
- 229960003260 chlorhexidine Drugs 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000004467 fishmeal Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000000415 inactivating effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 150000002894 organic compounds Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 235000008476 powdered milk Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 210000002374 sebum Anatomy 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20111186A JPS6357502A (ja) | 1986-08-26 | 1986-08-26 | 手指消毒用組成物 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20111186A JPS6357502A (ja) | 1986-08-26 | 1986-08-26 | 手指消毒用組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6357502A JPS6357502A (ja) | 1988-03-12 |
| JPH0563446B2 true JPH0563446B2 (enrdf_load_stackoverflow) | 1993-09-10 |
Family
ID=16435583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP20111186A Granted JPS6357502A (ja) | 1986-08-26 | 1986-08-26 | 手指消毒用組成物 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6357502A (enrdf_load_stackoverflow) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0774252A4 (en) * | 1994-05-06 | 2000-04-26 | Kanebo Ltd | CYTOKIN POTENTIATOR AND MEDICINE AGAINST DISEAS IN WHICH THE CYTOKIN ACTIVITY IS REDUCED |
| JP3636611B2 (ja) * | 1999-03-19 | 2005-04-06 | 日華化学株式会社 | 殺菌消毒剤組成物 |
| JP2002114616A (ja) * | 2000-10-12 | 2002-04-16 | Ryoso:Kk | 除菌剤とそれを用いた消毒方法 |
| ATE375719T1 (de) * | 2002-02-28 | 2007-11-15 | Ecolab Inc | Antimikrobielle zusammensetzungen enthaltend diester dicarbonsäuren und dessen verwendung |
-
1986
- 1986-08-26 JP JP20111186A patent/JPS6357502A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6357502A (ja) | 1988-03-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
| EXPY | Cancellation because of completion of term |