JPH0559119B2 - - Google Patents

Info

Publication number
JPH0559119B2
JPH0559119B2 JP2951284A JP2951284A JPH0559119B2 JP H0559119 B2 JPH0559119 B2 JP H0559119B2 JP 2951284 A JP2951284 A JP 2951284A JP 2951284 A JP2951284 A JP 2951284A JP H0559119 B2 JPH0559119 B2 JP H0559119B2
Authority
JP
Japan
Prior art keywords
group
aroylthymidine
general formula
derivative according
mmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2951284A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60174797A (ja
Inventor
Setsuo Fujii
Bonpei Yasui
Kazuko Ando
Iwao Hashimoto
Hikari Nagatomi
Tomohisa Myamoto
Masatoshi Shiga
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis KK
Original Assignee
Marion Merrell Dow KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Marion Merrell Dow KK filed Critical Marion Merrell Dow KK
Priority to JP2951284A priority Critical patent/JPS60174797A/ja
Publication of JPS60174797A publication Critical patent/JPS60174797A/ja
Publication of JPH0559119B2 publication Critical patent/JPH0559119B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2951284A 1984-02-21 1984-02-21 Ν−アロイルチミジン誘導体ならびに抗腫瘍活性物質の毒性低下剤 Granted JPS60174797A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2951284A JPS60174797A (ja) 1984-02-21 1984-02-21 Ν−アロイルチミジン誘導体ならびに抗腫瘍活性物質の毒性低下剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2951284A JPS60174797A (ja) 1984-02-21 1984-02-21 Ν−アロイルチミジン誘導体ならびに抗腫瘍活性物質の毒性低下剤

Publications (2)

Publication Number Publication Date
JPS60174797A JPS60174797A (ja) 1985-09-09
JPH0559119B2 true JPH0559119B2 (enrdf_load_html_response) 1993-08-30

Family

ID=12278148

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2951284A Granted JPS60174797A (ja) 1984-02-21 1984-02-21 Ν−アロイルチミジン誘導体ならびに抗腫瘍活性物質の毒性低下剤

Country Status (1)

Country Link
JP (1) JPS60174797A (enrdf_load_html_response)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108350018A (zh) * 2015-11-17 2018-07-31 日产化学工业株式会社 寡核苷酸的制造方法

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7776838B1 (en) 1987-10-28 2010-08-17 Wellstat Therapeutics Corporation Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
KR930003495B1 (ko) * 1987-10-28 1993-05-01 프로-뉴우런 인코포레이팃드 아실 데옥시리보뉴클레오시드 유도체 및 그의 사용
US5470838A (en) * 1987-10-28 1995-11-28 Pro-Neuron, Inc. Method of delivering exogenous uridine or cytidine using acylated uridine or cytidine
JP2637534B2 (ja) * 1987-10-28 1997-08-06 プロ−ニューロン，インコーポレーテッド アシルデオキシリボヌクレオシド誘導体およびその使用
US6329350B1 (en) 1987-10-28 2001-12-11 Pro-Neuron, Inc. Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
US5736531A (en) * 1987-10-28 1998-04-07 Pro-Neuron, Inc. Compositions of chemotherapeutic agent or antiviral agent with acylated pyrimidine nucleosides
AU2789989A (en) * 1987-10-28 1989-05-23 Pro-Neuron, Inc. Acylated uridine and cytidine and uses thereof
US6020322A (en) * 1993-11-09 2000-02-01 Pro-Neuron, Inc. Acyl deoxyribonucleoside derivatives and uses thereof
US5691320A (en) 1987-10-28 1997-11-25 Pro-Neuron, Inc. Acylated pyrimidine nucleosides for treatment of systemic inflammation and inflammatory hepatitis
US5968914A (en) * 1987-10-28 1999-10-19 Pro-Neuron, Inc. Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
KR100315890B1 (ko) * 1992-12-08 2002-06-27 마이클 바마트 전신염증및염증성간염치료용피리미딘누클레오티드전구체
AU6081294A (en) * 1993-05-14 1994-12-12 Pro-Neuron, Inc. Treatment of chemotherapeutic agent and antiviral agent toxicity with acylated pyrimidine nucleosides
AU1436995A (en) * 1993-12-30 1995-07-17 Chemgenes Corporation Synthesis of propargyl modified nucleosides and phosphoramidites and their incorporation into defined sequence oligonucleotides
AU712679B2 (en) 1994-07-01 1999-11-11 Pro-Neuron, Inc. Pyrimidine nucleotide precursors for treatment of systemic inflammation and inflammatory hepatitis
US6472378B2 (en) 1998-08-31 2002-10-29 Pro-Neuron, Inc. Compositions and methods for treatment of mitochondrial diseases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108350018A (zh) * 2015-11-17 2018-07-31 日产化学工业株式会社 寡核苷酸的制造方法

Also Published As

Publication number Publication date
JPS60174797A (ja) 1985-09-09

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