JPH05508220A - 抗IgE自己抗体の検出および調製法およびこれら抗体の診断および治療組成物中での活性剤としての使用 - Google Patents
抗IgE自己抗体の検出および調製法およびこれら抗体の診断および治療組成物中での活性剤としての使用Info
- Publication number
- JPH05508220A JPH05508220A JP91508475A JP50847591A JPH05508220A JP H05508220 A JPH05508220 A JP H05508220A JP 91508475 A JP91508475 A JP 91508475A JP 50847591 A JP50847591 A JP 50847591A JP H05508220 A JPH05508220 A JP H05508220A
- Authority
- JP
- Japan
- Prior art keywords
- ige
- antibodies
- autoantibodies
- recombinant
- antibody
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- JXYWFNAQESKDNC-BTJKTKAUSA-N (z)-4-hydroxy-4-oxobut-2-enoate;2-[(4-methoxyphenyl)methyl-pyridin-2-ylamino]ethyl-dimethylazanium Chemical compound OC(=O)\C=C/C(O)=O.C1=CC(OC)=CC=C1CN(CCN(C)C)C1=CC=CC=N1 JXYWFNAQESKDNC-BTJKTKAUSA-N 0.000 description 1
- 208000012657 Atopic disease Diseases 0.000 description 1
- 229940090898 Desensitizer Drugs 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 102000009438 IgE Receptors Human genes 0.000 description 1
- 108010073816 IgE Receptors Proteins 0.000 description 1
- 238000012404 In vitro experiment Methods 0.000 description 1
- 241000899717 Itaya Species 0.000 description 1
- 240000004658 Medicago sativa Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 description 1
- 241001424341 Tara spinosa Species 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4283—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig
- C07K16/4291—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an allotypic or isotypic determinant on Ig against IgE
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/548—Carbohydrates, e.g. dextran
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/24—Immunology or allergic disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Rheumatology (AREA)
- Rehabilitation Therapy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002086605A CA2086605A1 (fr) | 1991-05-10 | 1991-05-10 | Methodes de detection et de preparation des auto-anticorps anti-ige et utilisation de ces anticorps comme agents actifs dans des compositions diagnostiques et therapeutiques |
PCT/EP1991/000881 WO1992021031A1 (fr) | 1991-05-10 | 1991-05-10 | PROCEDE DE DETECTION ET DE PREPARATION D'AUTOANTICORPS ANTI-IgE, ET UTILISATION DE CES ANTICORPS COMME AGENTS ACTIFS DANS DES COMPOSITIONS A USAGE THERAPEUTIQUE ET DIAGNOSTIQUE |
Publications (1)
Publication Number | Publication Date |
---|---|
JPH05508220A true JPH05508220A (ja) | 1993-11-18 |
Family
ID=4150928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP91508475A Pending JPH05508220A (ja) | 1991-05-10 | 1991-05-10 | 抗IgE自己抗体の検出および調製法およびこれら抗体の診断および治療組成物中での活性剤としての使用 |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0538266A1 (fr) |
JP (1) | JPH05508220A (fr) |
CA (1) | CA2086605A1 (fr) |
WO (1) | WO1992021031A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011163992A (ja) * | 2010-02-12 | 2011-08-25 | Nitto Boseki Co Ltd | Ftcdとその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法 |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19505266C1 (de) * | 1995-02-16 | 1996-10-02 | Brahms Diagnostica Gmbh | Verwendung von polyklonalen humanen anti-hTg-Autoantikörpern als Reagenz für die klinische Diagnostik von Schilddrüsen-Autoimmunerkrankungen sowie Reagenziensatz für eine Bestimmung von anti-hTg-Autoantikörpern in Patientenseren |
EP1671646A3 (fr) * | 1998-09-18 | 2007-08-29 | Dynavax Technologies Corporation | Procédés de traitement de troubles associés à IgE et compositions pouvant être utilisées à cet effet. |
JP2003524602A (ja) * | 1998-09-18 | 2003-08-19 | ダイナバックス テクノロジーズ コーポレイション | IgE関連疾患の治療方法と、その治療において使用する組成物 |
US6787524B2 (en) | 2000-09-22 | 2004-09-07 | Tanox, Inc. | CpG oligonucleotides and related compounds for enhancing ADCC induced by anti-IgE antibodies |
RU2006134031A (ru) * | 2004-02-26 | 2008-04-10 | Альк-Абелло А/С (Dk) | Способ оценки терапевтического потенциала вакцины для введения через слизистые оболочки |
AU2006251647A1 (en) | 2005-05-20 | 2006-11-30 | Genentech, Inc. | Pretreatment of a biological sample from an autoimmune disease subject |
GT200800034A (es) * | 2007-04-02 | 2010-03-16 | Anticuerpos anti-ige | |
CN113583134B (zh) * | 2020-04-30 | 2024-06-04 | 天辰生物医药(苏州)有限公司 | 分离的抗原结合蛋白及其用途 |
-
1991
- 1991-05-10 JP JP91508475A patent/JPH05508220A/ja active Pending
- 1991-05-10 WO PCT/EP1991/000881 patent/WO1992021031A1/fr not_active Application Discontinuation
- 1991-05-10 CA CA002086605A patent/CA2086605A1/fr not_active Abandoned
- 1991-05-10 EP EP91909250A patent/EP0538266A1/fr not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2011163992A (ja) * | 2010-02-12 | 2011-08-25 | Nitto Boseki Co Ltd | Ftcdとその自己抗体との複合体の免疫測定方法、それに用いるキット及びそれを用いた癌判定方法 |
Also Published As
Publication number | Publication date |
---|---|
CA2086605A1 (fr) | 1992-11-11 |
EP0538266A1 (fr) | 1993-04-28 |
WO1992021031A1 (fr) | 1992-11-26 |
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