JPH0524892B2 - - Google Patents
Info
- Publication number
- JPH0524892B2 JPH0524892B2 JP60064692A JP6469285A JPH0524892B2 JP H0524892 B2 JPH0524892 B2 JP H0524892B2 JP 60064692 A JP60064692 A JP 60064692A JP 6469285 A JP6469285 A JP 6469285A JP H0524892 B2 JPH0524892 B2 JP H0524892B2
- Authority
- JP
- Japan
- Prior art keywords
- arbutin
- skin diseases
- agent
- drug
- present
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- BJRNKVDFDLYUGJ-RMPHRYRLSA-N hydroquinone O-beta-D-glucopyranoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-RMPHRYRLSA-N 0.000 claims description 17
- 229960000271 arbutin Drugs 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- BJRNKVDFDLYUGJ-UHFFFAOYSA-N p-hydroxyphenyl beta-D-alloside Natural products OC1C(O)C(O)C(CO)OC1OC1=CC=C(O)C=C1 BJRNKVDFDLYUGJ-UHFFFAOYSA-N 0.000 claims description 8
- 208000017520 skin disease Diseases 0.000 claims description 8
- 239000003470 adrenal cortex hormone Substances 0.000 claims description 6
- 239000003814 drug Substances 0.000 claims description 6
- 229940079593 drug Drugs 0.000 claims description 6
- 206010012442 Dermatitis contact Diseases 0.000 description 5
- 208000010247 contact dermatitis Diseases 0.000 description 5
- 239000002674 ointment Substances 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- 230000003449 preventive effect Effects 0.000 description 5
- 230000001225 therapeutic effect Effects 0.000 description 5
- 206010015150 Erythema Diseases 0.000 description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 4
- 231100000321 erythema Toxicity 0.000 description 4
- 230000006698 induction Effects 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 3
- 238000010171 animal model Methods 0.000 description 3
- 239000006071 cream Substances 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000002474 experimental method Methods 0.000 description 3
- 239000000118 hair dye Substances 0.000 description 3
- 230000008961 swelling Effects 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 2
- 206010012438 Dermatitis atopic Diseases 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 208000024780 Urticaria Diseases 0.000 description 2
- 230000001919 adrenal effect Effects 0.000 description 2
- 201000008937 atopic dermatitis Diseases 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 239000003246 corticosteroid Substances 0.000 description 2
- 201000005884 exanthem Diseases 0.000 description 2
- BXWNKGSJHAJOGX-UHFFFAOYSA-N hexadecan-1-ol Chemical compound CCCCCCCCCCCCCCCCO BXWNKGSJHAJOGX-UHFFFAOYSA-N 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 230000007803 itching Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 235000019271 petrolatum Nutrition 0.000 description 2
- 229960005205 prednisolone Drugs 0.000 description 2
- OIGNJSKKLXVSLS-VWUMJDOOSA-N prednisolone Chemical compound O=C1C=C[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OIGNJSKKLXVSLS-VWUMJDOOSA-N 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 239000003871 white petrolatum Substances 0.000 description 2
- 208000019872 Drug Eruptions Diseases 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 241000699670 Mus sp. Species 0.000 description 1
- 229920002675 Polyoxyl Polymers 0.000 description 1
- 240000003152 Rhus chinensis Species 0.000 description 1
- 235000014220 Rhus chinensis Nutrition 0.000 description 1
- 206010039793 Seborrhoeic dermatitis Diseases 0.000 description 1
- 206010041303 Solar dermatitis Diseases 0.000 description 1
- 244000299461 Theobroma cacao Species 0.000 description 1
- 235000009470 Theobroma cacao Nutrition 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 210000004404 adrenal cortex Anatomy 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 229960004311 betamethasone valerate Drugs 0.000 description 1
- SNHRLVCMMWUAJD-SUYDQAKGSA-N betamethasone valerate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(OC(=O)CCCC)[C@@]1(C)C[C@@H]2O SNHRLVCMMWUAJD-SUYDQAKGSA-N 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 239000007765 cera alba Substances 0.000 description 1
- 229960000541 cetyl alcohol Drugs 0.000 description 1
- 235000012000 cholesterol Nutrition 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 210000000624 ear auricle Anatomy 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 208000027866 inflammatory disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000401 methanolic extract Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 229930014626 natural product Natural products 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 208000008742 seborrheic dermatitis Diseases 0.000 description 1
- 231100000046 skin rash Toxicity 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 210000001635 urinary tract Anatomy 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60064692A JPS61225124A (ja) | 1985-03-28 | 1985-03-28 | 皮膚疾患用剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60064692A JPS61225124A (ja) | 1985-03-28 | 1985-03-28 | 皮膚疾患用剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61225124A JPS61225124A (ja) | 1986-10-06 |
| JPH0524892B2 true JPH0524892B2 (enrdf_load_stackoverflow) | 1993-04-09 |
Family
ID=13265451
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP60064692A Granted JPS61225124A (ja) | 1985-03-28 | 1985-03-28 | 皮膚疾患用剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61225124A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2744366B1 (fr) * | 1996-02-06 | 1998-03-27 | Serobiologiques Lab Sa | Utilisation d'extraits de la plante uva ursi et/ou de la plante lespedeza capitata et compositions cosmetique et pharmaceutique comportant de tels extraits |
-
1985
- 1985-03-28 JP JP60064692A patent/JPS61225124A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61225124A (ja) | 1986-10-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EXPY | Cancellation because of completion of term |