JPH0441123B2 - - Google Patents
Info
- Publication number
- JPH0441123B2 JPH0441123B2 JP58145708A JP14570883A JPH0441123B2 JP H0441123 B2 JPH0441123 B2 JP H0441123B2 JP 58145708 A JP58145708 A JP 58145708A JP 14570883 A JP14570883 A JP 14570883A JP H0441123 B2 JPH0441123 B2 JP H0441123B2
- Authority
- JP
- Japan
- Prior art keywords
- hair growth
- hair
- hormone
- hormones
- adrenal cortical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000003779 hair growth Effects 0.000 claims description 24
- 239000003795 chemical substances by application Substances 0.000 claims description 12
- 239000003470 adrenal cortex hormone Substances 0.000 claims description 11
- DNXHEGUUPJUMQT-CBZIJGRNSA-N Estrone Chemical compound OC1=CC=C2[C@H]3CC[C@](C)(C(CC4)=O)[C@@H]4[C@@H]3CCC2=C1 DNXHEGUUPJUMQT-CBZIJGRNSA-N 0.000 claims description 8
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 6
- 239000011716 vitamin B2 Substances 0.000 claims description 4
- 239000007788 liquid Substances 0.000 claims description 3
- 239000008213 purified water Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 230000000694 effects Effects 0.000 description 12
- 239000005556 hormone Substances 0.000 description 11
- 229940088597 hormone Drugs 0.000 description 11
- 238000009472 formulation Methods 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- 230000000052 comparative effect Effects 0.000 description 3
- 210000003128 head Anatomy 0.000 description 3
- 239000004615 ingredient Substances 0.000 description 3
- 210000004761 scalp Anatomy 0.000 description 3
- 239000011782 vitamin Substances 0.000 description 3
- 235000013343 vitamin Nutrition 0.000 description 3
- 229930003231 vitamin Natural products 0.000 description 3
- 229940088594 vitamin Drugs 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 206010040880 Skin irritation Diseases 0.000 description 2
- 230000002503 metabolic effect Effects 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000036556 skin irritation Effects 0.000 description 2
- 231100000475 skin irritation Toxicity 0.000 description 2
- 235000015961 tonic Nutrition 0.000 description 2
- 230000001256 tonic effect Effects 0.000 description 2
- 229960000716 tonics Drugs 0.000 description 2
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 description 1
- 201000004384 Alopecia Diseases 0.000 description 1
- UYIFTLBWAOGQBI-BZDYCCQFSA-N Benzhormovarine Chemical compound C([C@@H]1[C@@H](C2=CC=3)CC[C@]4([C@H]1CC[C@@H]4O)C)CC2=CC=3OC(=O)C1=CC=CC=C1 UYIFTLBWAOGQBI-BZDYCCQFSA-N 0.000 description 1
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 description 1
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 description 1
- 239000004470 DL Methionine Substances 0.000 description 1
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 description 1
- 101100011509 Drosophila melanogaster Baldspot gene Proteins 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- LRJOMUJRLNCICJ-JZYPGELDSA-N Prednisolone acetate Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@@](C(=O)COC(=O)C)(O)[C@@]1(C)C[C@@H]2O LRJOMUJRLNCICJ-JZYPGELDSA-N 0.000 description 1
- DFPAKSUCGFBDDF-ZQBYOMGUSA-N [14c]-nicotinamide Chemical compound N[14C](=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-ZQBYOMGUSA-N 0.000 description 1
- 230000001919 adrenal effect Effects 0.000 description 1
- 230000001780 adrenocortical effect Effects 0.000 description 1
- 208000004631 alopecia areata Diseases 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 229940046978 chlorpheniramine maleate Drugs 0.000 description 1
- 239000003246 corticosteroid Substances 0.000 description 1
- 229960001334 corticosteroids Drugs 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 229950002007 estradiol benzoate Drugs 0.000 description 1
- 230000003325 follicular Effects 0.000 description 1
- 208000024963 hair loss Diseases 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229940041616 menthol Drugs 0.000 description 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N methionine Chemical compound CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 235000006109 methionine Nutrition 0.000 description 1
- 230000002611 ovarian Effects 0.000 description 1
- 229960002800 prednisolone acetate Drugs 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- ZUFQODAHGAHPFQ-UHFFFAOYSA-N pyridoxine hydrochloride Chemical compound Cl.CC1=NC=C(CO)C(CO)=C1O ZUFQODAHGAHPFQ-UHFFFAOYSA-N 0.000 description 1
- 229960004172 pyridoxine hydrochloride Drugs 0.000 description 1
- 235000019171 pyridoxine hydrochloride Nutrition 0.000 description 1
- 239000011764 pyridoxine hydrochloride Substances 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 230000008093 supporting effect Effects 0.000 description 1
- 230000003813 thin hair Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
〔産業上の利用分野〕
本発明は、人体頭皮に塗布して極めて有効な発
毛作用を現わす発毛剤に関する。
〔従来の技術〕
一般に養毛剤または発毛剤と称するものの代表
的成分は女性ホルモンあるいは副腎皮質ホルモン
である例が多い。男性に禿頭が多く女性に禿頭が
ない理由は、男性が男性ホルモン過多になりやす
く女性にはそのようなことがないことにあるらし
いとは、実証されてはいないが広く信ぜられてい
る。
養毛剤、発毛剤に女性ホルモンを用いる例が多
いのは、この関係に基づいて男性の男性ホルモン
過多である皮膚組織に女性ホルモンを補う効果を
狙つていることは明らかである。従来、女性ホル
モン、ビタミン（ＥまたはＨ）、アルコール、メ
ントールなどを加えたものを成分とするものが知
られている。しかしながら、例外なく発毛効果が
ないのが実態であり、また養毛剤と称するもの
も、使用者が効果を認め得ないながら万一の期待
を持つて使用しているもののようである。
〔発明が解決しようとする課題〕
しかも、不適当な濃度のホルモン剤を使用する
ために皮膚に炎症を起こし、併せて配合したアル
コールの刺激によつて発毛しないのみならず脱毛
する例が多い。要するに、発毛能力のある発毛剤
が皆無である現状にある。
本発明者は、以上の市販発毛剤の実態にかんが
み研究を重ねた。女性ホルモン（卵胞ホルモン）
あるいは副腎皮質ホルモンをそれぞれ単独に使用
することは、その特性から見て合理性があるがそ
の濃度条件には研究の余地があると考えられる。
円形脱毛症には0.5％濃度の副腎皮質ホルモンが
使用されるが、長期使用の場合は濃度に問題があ
る。そこで、従来考えられず試みられた例もない
超低濃度域の可能性を試みる必要がある。卵胞ホ
ルモンと副腎皮質ホルモンとを併用した例は未だ
ないが、併用しかつ特定混合比とすることに可能
性がある。また、蛋白質の代謝作用剤としてビタ
ミンを使用する例が従来からあるが、適確で強い
代謝作用を発揮する組合わせを検索することが重
要である。
本発明は、以上の問題点にかんがみて検索の
上、頭皮に塗布して発毛する発毛剤の創製を目的
としている。
〔課題を解決するための手段〕
本発明は、卵胞ホルモン、副腎皮質ホルモン及
びビタミンB2を主成分とする超低濃度水溶液に
よつてなる頭髪発毛剤である。
次に発明に至る経過を説明する。卵胞ホルモ
ン、副腎皮質ホルモン及びビタミンB2の発毛作
用につき低濃度域を検索した。方法は調整液１c.c.
を１日２回頭皮に塗布した。結果を第１表に示
す。
[Industrial Application Field] The present invention relates to a hair growth agent that exhibits an extremely effective hair growth effect when applied to the human scalp. [Prior Art] The typical ingredients of what are generally called hair tonics or hair growth agents are often female hormones or adrenal cortical hormones. It is widely believed, although not proven, that the reason why more men are bald than women is that men tend to have an excess of male hormones, which women do not. Based on this relationship, it is clear that the reason why female hormones are often used in hair tonics and hair growth agents is to supplement female hormones to men's skin tissue, which has an excess of male hormones. Conventionally, products containing female hormones, vitamins (E or H), alcohol, menthol, etc. are known as ingredients. However, the reality is that without exception, they do not have any effect on hair growth, and it seems that even the so-called hair-growth agents are used by users with high expectations even though they are unable to see any effect. [Problem to be solved by the invention] Furthermore, the use of inappropriate concentrations of hormones causes skin irritation, and the combined alcohol stimulation often results in not only hair not growing but also hair loss. . In short, the current situation is that there are no hair growth agents that have the ability to grow hair. The present inventor conducted repeated research in view of the actual situation of the above-mentioned commercially available hair growth agents. Female hormones (ovarian hormones)
Alternatively, it is reasonable to use each of the adrenocortical hormones alone in view of their characteristics, but there is room for research on their concentration conditions.
Adrenal corticosteroids at a concentration of 0.5% are used to treat alopecia areata, but there are problems with the concentration when used over a long period of time. Therefore, it is necessary to explore possibilities in the ultra-low concentration range, which have never been considered or attempted before. Although there is no example yet of using follicular hormone and adrenal cortical hormone in combination, there is a possibility of using them together and at a specific mixing ratio. In addition, there have been examples of using vitamins as agents for protein metabolism, but it is important to search for a combination that exhibits an accurate and strong metabolic effect. In view of the above problems, the present invention aims to create a hair growth agent that can be applied to the scalp to grow hair. [Means for Solving the Problems] The present invention is a hair growth agent comprising an ultra-low concentration aqueous solution containing follicular hormone, adrenal cortical hormone, and vitamin B2 as main components. Next, the process leading to the invention will be explained. We searched for the low concentration range of follicular hormone, adrenal cortical hormone, and vitamin B2 for their hair growth effects. The method is 1 c.c. of adjustment liquid.
was applied to the scalp twice a day. The results are shown in Table 1.
次に、本発明の作用について説明する。卵胞ホ
ルモン及び副腎皮質ホルモンを超低濃度としたた
めに皮膚炎症を起こすことがないばかりでなく、
この液を塗布して皮膚組織に吸収蓄積するとして
も炎症を起こしかつ発毛を妨げるほどの量に達す
ることがない。しかも、この超低濃度において発
毛作用が現れることを確認した。副腎皮質ホルモ
ンは卵胞ホルモンの発毛効果を強める作用があ
り、卵胞ホルモン対副腎皮質ホルモンの重量比の
値が0.1〜0.4の範囲で発毛効果を示すことも確認
した。また、ビタミンB2を発毛剤に用いた従来
例はないが、本発明において初めてビタミンB2
を用い、しかも３主成分のうちの１主成分として
顕著な効果を示すことを認めた。配合例Ｃの各成
分は、欠くべからざる主成分と異なり、脇役的効
果を示すものである。マレイン酸クロルフエニラ
ミンは副腎皮質ホルモンの作用を強めるものであ
り、塩酸ピリドキシン、ニコチン酸アミド、パン
トテニルアルコール、DL−メチオニンは何れも
ビタミンB2の蛋白質代謝作用を強める効果があ
ることを認めた。
〔実施例〕
前記配合例Ｂ液を、１日１〜２回塗布し、１か
月で約50〜100c.c.を使用する割合で試験した。60
名に適用したが、全員に発毛と白髪の黒変を認め
た。若禿には３か月で効果が認められ、75才の男
性にも発毛を認めた。
次に数例を示す。
(1) 30才の男、３か月間に300c.c.使用、１日１〜
２回塗布、左側頭部手のひら大の禿が完全発
毛。
(2) 43才の男、２か月間に120c.c.使用、１日１〜
２回塗布、前頭部の禿が完全発毛。
(3) 30才の男、２か月間に120c.c.使用、１日１回
塗布、頭頂部の禿が完全発毛。
(4) 60才の男、1.5か月間に200c.c.使用、１日２回
塗布、白髪と薄毛が黒変し発毛。
比較例 １
前記配合例Ｃ液を実施例と同様にして５名に３
か月間適用したが発毛を認めなかつた。
比較例 ２
前記配合例Ａから酢酸プレドニゾロンを除いた
液を用いた他は実施例と同様にして５名に３か月
間適用したが、発毛を認めなかつた。
比較例 ３
前記配合例Ａから安息香酸エストラジオールを
除いた液を用いた他は実施例と同様にして５名に
３か月間適用したが、発毛を認めなかつた。
〔発明の効果〕
卵胞ホルモン、副腎皮質ホルモン及びビタミン
B2３成分の超低濃度配合液によつて発毛が可能
である。
Next, the operation of the present invention will be explained. Due to the extremely low concentration of follicular hormone and adrenal cortical hormone, it not only does not cause skin irritation, but also
Even if this liquid is applied and absorbed and accumulated in the skin tissue, the amount will not reach a level that causes inflammation and inhibits hair growth. Moreover, it was confirmed that the hair growth effect appeared at this ultra-low concentration. It was also confirmed that adrenal cortical hormone has the effect of enhancing the hair growth effect of follicular hormone, and that it exhibits a hair growth effect when the weight ratio of follicular hormone to adrenal cortical hormone is in the range of 0.1 to 0.4. In addition, although there is no conventional example of using vitamin B 2 in a hair growth agent, the present invention is the first to use vitamin B 2 as a hair growth agent.
was used, and it was found that it showed a remarkable effect as one of the three main components. Each component of Formulation Example C is different from the indispensable main component and exhibits supporting effects. Chlorpheniramine maleate strengthens the action of adrenal cortical hormones, and pyridoxine hydrochloride, nicotinamide, pantothenyl alcohol, and DL-methionine are all recognized to have the effect of strengthening the protein metabolic action of vitamin B2. Ta. [Example] The above-mentioned Formulation Example B solution was applied once or twice a day, and tested at a rate of about 50 to 100 c.c. per month. 60
However, hair growth and blackening of gray hair were observed in all patients. It was effective for young bald people after three months, and hair growth was also observed in a 75-year-old man. Here are some examples: (1) 30-year-old man, using 300 c.c. for 3 months, 1 to 1 day a day
After applying it twice, the palm-sized bald spot on the left side of the head had completely grown hair. (2) 43-year-old man, using 120 c.c. for 2 months, 1 to 1 day a day
After applying twice, the bald area on the front of the head has completely grown back. (3) A 30-year-old man used 120 c.c. for 2 months, applied once a day, and the bald area on the top of his head had completely grown back. (4) A 60-year-old man used 200c.c. for 1.5 months, applied twice a day, and his gray and thinning hair turned black and grew back. Comparative Example 1 The above-mentioned Formulation Example C solution was given to 5 people in the same manner as in the example.
I applied it for a month, but no hair growth was observed. Comparative Example 2 This was applied to 5 people for 3 months in the same manner as in Example except that the solution from Formulation Example A except that prednisolone acetate was removed, but no hair growth was observed. Comparative Example 3 This was applied to 5 people for 3 months in the same manner as in Example except that the solution from Formulation Example A except that estradiol benzoate was removed, but no hair growth was observed. [Effects of the invention] Follicular hormones, adrenal cortical hormones and vitamins
Hair growth is possible with an ultra-low concentration solution containing the three B2 ingredients.
Claims (1)
モン0.018〜1.1mg、ビタミンB20.085〜5.1mgを主
成分として精製水100c.c.に均質に溶解し、かつ
（卵胞ホルモン）／（副腎皮質ホルモン）の重量
比の値を0.1〜0.4の範囲とする液からなることを
特徴とする頭髪の発毛剤。1 Homogeneously dissolved in 100 c.c. of purified water with 0.0033 to 0.2 mg of follicular hormone, 0.018 to 1.1 mg of adrenal cortical hormone, and 0.085 to 5.1 mg of vitamin B2 , and (follicular hormone)/(adrenal cortical hormone) A hair growth agent comprising a liquid having a weight ratio of 0.1 to 0.4.
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58145708A JPS6038313A (en) | 1983-08-11 | 1983-08-11 | Hair restorer |
| DE3417136A DE3417136C2 (en) | 1983-08-11 | 1984-05-09 | Hair restorer |
| KR1019840003033A KR860001587B1 (en) | 1983-08-11 | 1984-05-31 | Composition for the treatment of hair loss |
| FR8409594A FR2550448B1 (en) | 1983-08-11 | 1984-06-19 | HAIR GROWTH AGENT |
| CA000459176A CA1240618A (en) | 1983-08-11 | 1984-07-18 | Agent for regenerating the hair |
| GB08419228A GB2144991B (en) | 1983-08-11 | 1984-07-27 | Hair growth promotor |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58145708A JPS6038313A (en) | 1983-08-11 | 1983-08-11 | Hair restorer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6038313A JPS6038313A (en) | 1985-02-27 |
| JPH0441123B2 true JPH0441123B2 (en) | 1992-07-07 |
Family
ID=15391281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58145708A Granted JPS6038313A (en) | 1983-08-11 | 1983-08-11 | Hair restorer |
Country Status (6)
| Country | Link |
|---|---|
| JP (1) | JPS6038313A (en) |
| KR (1) | KR860001587B1 (en) |
| CA (1) | CA1240618A (en) |
| DE (1) | DE3417136C2 (en) |
| FR (1) | FR2550448B1 (en) |
| GB (1) | GB2144991B (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4100975A1 (en) * | 1991-01-15 | 1992-07-16 | Weuffen Wolfgang | Cosmetic or pharmaceutical preparations for improving hair quality and promoting hair growth |
| DE19509354A1 (en) * | 1994-12-08 | 1996-06-13 | Klett Loch Lore M | Combination preparation for promoting hair growth and possibly skin and nail growth and for preventing or eliminating hair loss |
| AU6434999A (en) * | 1998-09-28 | 2000-04-17 | Gavin Deon Petersen | Hair growth stimulant |
| WO2024175703A1 (en) * | 2023-02-24 | 2024-08-29 | Giuliani S.P.A. | Composition for improving the aesthetic appearance of hair and skin appendages |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5879913A (en) * | 1981-11-09 | 1983-05-13 | Taizo Ayukawa | Hair tonic composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2257223A1 (en) * | 1972-11-22 | 1974-06-12 | Fouad Dr Med Talabani | Hair growth and anti- hairloss compsn. - contg. mixts of androgen, oestrogen, corticoid and carriers |
-
1983
- 1983-08-11 JP JP58145708A patent/JPS6038313A/en active Granted
-
1984
- 1984-05-09 DE DE3417136A patent/DE3417136C2/en not_active Expired
- 1984-05-31 KR KR1019840003033A patent/KR860001587B1/en active
- 1984-06-19 FR FR8409594A patent/FR2550448B1/en not_active Expired
- 1984-07-18 CA CA000459176A patent/CA1240618A/en not_active Expired
- 1984-07-27 GB GB08419228A patent/GB2144991B/en not_active Expired
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5879913A (en) * | 1981-11-09 | 1983-05-13 | Taizo Ayukawa | Hair tonic composition |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6038313A (en) | 1985-02-27 |
| DE3417136C2 (en) | 1986-01-23 |
| DE3417136A1 (en) | 1985-02-21 |
| GB2144991A (en) | 1985-03-20 |
| KR850002395A (en) | 1985-05-13 |
| CA1240618A (en) | 1988-08-16 |
| GB2144991B (en) | 1987-04-15 |
| FR2550448A1 (en) | 1985-02-15 |
| KR860001587B1 (en) | 1986-10-13 |
| GB8419228D0 (en) | 1984-08-30 |
| FR2550448B1 (en) | 1987-04-17 |
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