JPH0438392B2 - - Google Patents

Info

Publication number
JPH0438392B2
JPH0438392B2 JP62193612A JP19361287A JPH0438392B2 JP H0438392 B2 JPH0438392 B2 JP H0438392B2 JP 62193612 A JP62193612 A JP 62193612A JP 19361287 A JP19361287 A JP 19361287A JP H0438392 B2 JPH0438392 B2 JP H0438392B2
Authority
JP
Japan
Prior art keywords
thymidine
purified
activity
complex
gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62193612A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6359886A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS6359886A publication Critical patent/JPS6359886A/ja
Publication of JPH0438392B2 publication Critical patent/JPH0438392B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C12N9/1211—Thymidine kinase (2.7.1.21)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
JP62193612A 1986-07-31 1987-07-30 胎児型精製チミジンキナーゼの製造方法 Granted JPS6359886A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8611101A FR2602242B1 (fr) 1986-07-31 1986-07-31 Thymidine kinase de type foetal purifiee
FR8611101 1986-07-31

Publications (2)

Publication Number Publication Date
JPS6359886A JPS6359886A (ja) 1988-03-15
JPH0438392B2 true JPH0438392B2 (enExample) 1992-06-24

Family

ID=9337917

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62193612A Granted JPS6359886A (ja) 1986-07-31 1987-07-30 胎児型精製チミジンキナーゼの製造方法

Country Status (14)

Country Link
EP (1) EP0255431B1 (enExample)
JP (1) JPS6359886A (enExample)
CN (1) CN87105215A (enExample)
AT (1) ATE68821T1 (enExample)
AU (1) AU594486B2 (enExample)
DE (1) DE3774025D1 (enExample)
DK (1) DK387387A (enExample)
ES (1) ES2038681T3 (enExample)
FR (1) FR2602242B1 (enExample)
GR (1) GR3003416T3 (enExample)
IE (1) IE61237B1 (enExample)
NZ (1) NZ221246A (enExample)
PT (1) PT85406B (enExample)
ZA (1) ZA875378B (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE239784T1 (de) * 1993-08-06 2003-05-15 Univ Brigham Young Monoklonale antikörper gegen isozyme der thymidinkinase
SE9401380D0 (sv) * 1994-04-22 1994-04-22 Sven Skog Ny celltillväxt-relaterad peptid och användning därav
CN1301821A (zh) * 1999-12-27 2001-07-04 上海博德基因开发有限公司 一种新的多肽——胸腺嘧啶核苷酸激酶11和编码这种多肽的多核苷酸
US7311906B2 (en) 2004-04-30 2007-12-25 Brigham Young University Anti-viral activity of an anti-thymidine kinase monoclonal antibody
US8551486B2 (en) 2004-05-21 2013-10-08 Savoy Pharmaceuticals, Inc. Monoclonal antibodies to human thymidine kinase to treat cancer
US7837998B2 (en) 2004-05-21 2010-11-23 Nathaniel Lallatin Anti-cancer activity of an anti-thymidine kinase monoclonal antibody
US9267948B2 (en) 2009-12-30 2016-02-23 Brigham Young University Compositions and methods for cancer management using antibodies binding to nucleotide salvage pathway enzymes and complexes thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2028588A1 (de) * 1970-06-10 1971-12-16 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V., 3400 Göttingen Verfahren zur Gewinnung von Thymidin-Kinase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
THE JOURNAL OF BIOLOGICAL CHEMISTRY=1976 *
THE JOURNAL OF BIOLOGICAL CHEMISTRY=1984 *

Also Published As

Publication number Publication date
JPS6359886A (ja) 1988-03-15
PT85406B (pt) 1990-04-30
DE3774025D1 (de) 1991-11-28
AU594486B2 (en) 1990-03-08
ES2038681T3 (es) 1993-08-01
EP0255431A1 (fr) 1988-02-03
AU7607587A (en) 1988-02-04
DK387387A (da) 1988-02-01
NZ221246A (en) 1991-05-28
FR2602242B1 (fr) 1989-05-26
ZA875378B (en) 1988-01-29
IE61237B1 (en) 1994-10-19
PT85406A (fr) 1987-08-01
DK387387D0 (da) 1987-07-24
ATE68821T1 (de) 1991-11-15
CN87105215A (zh) 1988-02-24
EP0255431B1 (fr) 1991-10-23
IE872064L (en) 1988-01-31
FR2602242A1 (fr) 1988-02-05
GR3003416T3 (en) 1993-02-17

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