JPH0437834B2 - - Google Patents

Info

Publication number
JPH0437834B2
JPH0437834B2 JP59053118A JP5311884A JPH0437834B2 JP H0437834 B2 JPH0437834 B2 JP H0437834B2 JP 59053118 A JP59053118 A JP 59053118A JP 5311884 A JP5311884 A JP 5311884A JP H0437834 B2 JPH0437834 B2 JP H0437834B2
Authority
JP
Japan
Prior art keywords
pyridine
dihydropyrazolo
cyclopentyl
nitrophenyl
carboxylate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59053118A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60197685A (ja
Inventor
Ikuo Adachi
Teruo Yamamori
Motohiko Ueda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP59053118A priority Critical patent/JPS60197685A/ja
Priority to DE8585103017T priority patent/DE3578177D1/de
Priority to EP85103017A priority patent/EP0157260B1/en
Priority to ES541910A priority patent/ES541910A0/es
Priority to DK122385A priority patent/DK122385A/da
Priority to AU40070/85A priority patent/AU575134B2/en
Priority to KR1019850001788A priority patent/KR910006646B1/ko
Priority to GB08507008A priority patent/GB2156348B/en
Publication of JPS60197685A publication Critical patent/JPS60197685A/ja
Priority to US07/099,907 priority patent/US4873334A/en
Publication of JPH0437834B2 publication Critical patent/JPH0437834B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP59053118A 1982-10-05 1984-03-19 ４，７―ジヒドロピラゾロ［３，４―ｂ］ピリジン誘導体とその製造法 Granted JPS60197685A (ja)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP59053118A JPS60197685A (ja) 1984-03-19 1984-03-19 ４，７―ジヒドロピラゾロ［３，４―ｂ］ピリジン誘導体とその製造法
DE8585103017T DE3578177D1 (de) 1984-03-19 1985-03-15 4,7-dihydropyrazolo(3,4-b)pyridin-derivate.
EP85103017A EP0157260B1 (en) 1984-03-19 1985-03-15 4,7-dihydropyrazolo(3,4-b)pyridine derivatives
AU40070/85A AU575134B2 (en) 1984-03-19 1985-03-18 4,7-dihydropyrazolo (3,4-b) pyridine derivatives
DK122385A DK122385A (da) 1984-03-19 1985-03-18 4,7-dihydropyrazolo(3,4-b)pyridinderivater
ES541910A ES541910A0 (es) 1984-03-19 1985-03-18 Procedimiento para la fabricacion de derivados de 4,7-dihi- dropirazolo (3,4-b)piridina
KR1019850001788A KR910006646B1 (ko) 1984-03-19 1985-03-19 4,7-디히드로피라졸[3,4-b]피리딘 유도체의 제조방법
GB08507008A GB2156348B (en) 1984-03-19 1985-03-19 4,7-dihydropyrazolo (3,4-b) pyridine derivatives
US07/099,907 US4873334A (en) 1982-10-05 1987-09-22 4,7-dihydropyrazolo(3,4-b) pyridine derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59053118A JPS60197685A (ja) 1984-03-19 1984-03-19 ４，７―ジヒドロピラゾロ［３，４―ｂ］ピリジン誘導体とその製造法

Publications (2)

Publication Number Publication Date
JPS60197685A JPS60197685A (ja) 1985-10-07
JPH0437834B2 true JPH0437834B2 (en, 2012) 1992-06-22

Family

ID=12933883

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59053118A Granted JPS60197685A (ja) 1982-10-05 1984-03-19 ４，７―ジヒドロピラゾロ［３，４―ｂ］ピリジン誘導体とその製造法

Country Status (8)

Country Link
EP (1) EP0157260B1 (en, 2012)
JP (1) JPS60197685A (en, 2012)
KR (1) KR910006646B1 (en, 2012)
AU (1) AU575134B2 (en, 2012)
DE (1) DE3578177D1 (en, 2012)
DK (1) DK122385A (en, 2012)
ES (1) ES541910A0 (en, 2012)
GB (1) GB2156348B (en, 2012)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6056979A (ja) * 1983-09-08 1985-04-02 Shionogi & Co Ltd ４，７−ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法
US6977262B2 (en) 2001-02-02 2005-12-20 Mitsubishi Pharma Corporation Dihydropyrazolopyridine compounds and pharmaceutical use thereof
CA2437215A1 (en) * 2001-02-02 2002-08-15 Mitsubishi Pharma Corporation Dihydropyrazolopyridine compounds and pharmaceutical use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3403158A (en) * 1966-03-11 1968-09-24 Upjohn Co 1h-pyrazolo[3, 4-b]pyridines
DE1670827C3 (de) * 1967-03-20 1974-10-24 Bayer Ag, 5090 Leverkusen 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin
US4038283A (en) * 1975-04-30 1977-07-26 E. R. Squibb & Sons, Inc. 4-Alkoxy or hydroxy derivatives of 2H-pyrazolo[3,4-b]pyridine-5-carboxylic acids and esters
US3985757A (en) * 1975-09-17 1976-10-12 E. R. Squibb & Sons, Inc. Pyrazolopyridine ketones
CH635840A5 (en) * 1978-01-01 1983-04-29 Thomae Gmbh Dr K 1H-Pyrazolo[3,4-b]pyridines
JPS5965089A (ja) * 1982-10-05 1984-04-13 Shionogi & Co Ltd ジヒドロピラゾロ〔３，４−ｂ〕ピリジン誘導体およびその製造法
GR79111B (en, 2012) * 1982-12-20 1984-10-02 Lepetit Spa

Also Published As

Publication number Publication date
EP0157260B1 (en) 1990-06-13
GB8507008D0 (en) 1985-04-24
ES8602787A1 (es) 1985-12-01
KR850006406A (ko) 1985-10-05
KR910006646B1 (ko) 1991-08-30
DK122385A (da) 1985-09-20
AU4007085A (en) 1985-09-26
GB2156348A (en) 1985-10-09
DE3578177D1 (de) 1990-07-19
JPS60197685A (ja) 1985-10-07
EP0157260A1 (en) 1985-10-09
ES541910A0 (es) 1985-12-01
AU575134B2 (en) 1988-07-21
GB2156348B (en) 1988-05-05
DK122385D0 (da) 1985-03-18

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