JPH0424433Y2 - - Google Patents
Info
- Publication number
- JPH0424433Y2 JPH0424433Y2 JP6380484U JP6380484U JPH0424433Y2 JP H0424433 Y2 JPH0424433 Y2 JP H0424433Y2 JP 6380484 U JP6380484 U JP 6380484U JP 6380484 U JP6380484 U JP 6380484U JP H0424433 Y2 JPH0424433 Y2 JP H0424433Y2
- Authority
- JP
- Japan
- Prior art keywords
- amount
- sample
- specimen
- setting
- nozzle
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000007788 liquid Substances 0.000 claims description 17
- 238000007599 discharging Methods 0.000 claims description 4
- 238000003556 assay Methods 0.000 claims description 2
- 238000004458 analytical method Methods 0.000 description 9
- 239000012895 dilution Substances 0.000 description 4
- 238000010790 dilution Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 239000012530 fluid Substances 0.000 description 3
- 238000010586 diagram Methods 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 230000007423 decrease Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
- Sampling And Sample Adjustment (AREA)
Description
【考案の詳細な説明】
(イ) 産業上の利用分野
この考案は間児童分析装置などに用いられる検
体分注器に関する。[Detailed description of the invention] (a) Industrial application field This invention relates to a sample dispenser used in child analyzers and the like.
(ロ) 従来の技術
自動分析装置などに用いられる従来の液体分注
器は、検体を、予め内部液を満たしておいた検体
ノズルを通じて吸引し、これを内部液で押出して
反応管に注入する作動を基本的に行うものであ
る。そして検体は分析に必要な検体必要量だけで
はなくて検体必要量の多少にかかわらず一定量の
余剰量をプラスして吸引採取され、分析が終了す
れば残りの検体は内部液で押出して破棄され検体
ノズルは内部液で満たされる。そして検体必要量
が多量である場合(同一検体の分析項目が多いと
きとか同一分析の繰り返しが多いとき)は検体の
余剰量を多くすることができず、検体ノズルの奥
部に吸引された検体が検体ノズル内壁に付着して
いる内部液によつて希釈されるという影響が大き
くなり分析誤差の原因となる。したがつて経験的
に適切な一定の余剰量の検体が吸引採取されてい
る。一方検体必要量が少量の場合は上記のごとき
内部液により希釈の影響が小さいので、上記の検
体必要量が多量の場合よりも少ない余剰量で充分
であるが、検体必要量に対する排棄検体量が大き
く無駄になつている。(b) Conventional technology A conventional liquid pipettor used in automatic analyzers, etc. aspirates a sample through a sample nozzle that is filled with an internal liquid in advance, pushes it out with the internal liquid, and injects it into a reaction tube. It basically performs the operation. Then, the specimen is collected by suction not only with the required amount of specimen needed for analysis, but also with a certain amount of surplus regardless of the amount of specimen required, and when the analysis is completed, the remaining specimen is pushed out with internal fluid and discarded. The sample nozzle is filled with internal liquid. When the required amount of sample is large (when the same sample has many analysis items or the same analysis is repeated frequently), it is not possible to increase the surplus amount of sample, and the sample is sucked into the deep part of the sample nozzle. is diluted by the internal liquid adhering to the inner wall of the sample nozzle, which increases the influence and causes analysis errors. Therefore, empirically, a certain appropriate surplus amount of specimen is collected by aspiration. On the other hand, when the required amount of specimen is small, the effect of dilution due to the internal solution as described above is small, so a smaller surplus amount is sufficient than when the required amount of specimen is large, but the amount of discarded specimen relative to the required amount of specimen is sufficient. is being wasted to a large extent.
(ハ) 目的
この考案の目的は、検体必要量が多い場合には
検体の余剰量を増やして内部液による検体が希釈
される影響を少なくし、一方検体必要量が少ない
場合は検体余剰量を減らして検体の無駄な排棄を
減らすように、検定必要量に対応して検体余剰量
を増減し必要かつ充分な検体余剰量を採取する検
体分注器を提供するにある。(c) Purpose The purpose of this device is to increase the surplus amount of specimen when the required amount of specimen is large and to reduce the effect of dilution of the specimen by internal fluid, and on the other hand, when the required amount of specimen is small, to increase the surplus amount of specimen. To provide a specimen dispenser that increases or decreases the surplus specimen amount in accordance with the required amount for assay and collects a necessary and sufficient surplus specimen amount so as to reduce wasteful disposal of the specimen.
(ニ) 構成
この考案は、内部液吸引収ノズル、液体試料の
吸引と吐出とを行うための検体ノズル、切換手段
によつて選択的に前記内部液吸引ノズルもしくは
前記検体ノズルに連通されるプランジヤポンプ手
段及びこれらの手段の作動を制御する手段を少な
くとも具備し、この制御手段が必要検体量Aの設
定手段、必要検体量に乗ずる定数Kの設定手段、
一定検体量Bの設定手段、及びこれらの手段から
の信号によつて吸引検体量〔A(1+K+B〕を
演算してこの検体量を吸引吐出させるべくプラン
ジヤポンプ手段に作動信号を出力する演算手段を
具備することを特徴とする検体分注器を提供する
ものである。(D) Structure This invention includes an internal liquid suction nozzle, a specimen nozzle for suctioning and discharging a liquid sample, and a plunger that is selectively communicated with the internal liquid suction nozzle or the specimen nozzle by a switching means. It comprises at least a pump means and a means for controlling the operation of these means, and the control means includes a means for setting a required sample amount A, a means for setting a constant K by which the required sample amount is multiplied,
means for setting a constant sample amount B, and calculating means for calculating the amount of aspirated sample [A(1+K+B)] based on the signals from these means and outputting an operating signal to the plunger pump means for aspirating and discharging this sample amount. The present invention provides a sample dispenser characterized by comprising:
この考案の検体分注器は、検体必要量Aと、こ
れに比例する余剰量AKと、Aとは無関係に一定
量の余剰量Bとの合計量を吸引採取し、必要量づ
つを反応管に注入することができる。余剰量Bは
検体必要量Aが著しく少量の場合に余剰量AKだ
けでは少ないために必要な量である。そしてK及
びBの数値は分析項目などによつて適宜選択して
設定される。 The sample dispenser of this invention aspirates the total amount of the required sample amount A, a surplus amount AK proportional to this, and a constant surplus amount B independent of A, and transfers each required amount into a reaction tube. can be injected into. The surplus amount B is a necessary amount because the surplus amount AK alone is insufficient when the required sample amount A is extremely small. The numerical values of K and B are appropriately selected and set depending on the analysis items.
(ホ) 実施例
この考案を第1図に示す一実施例によつて説明
するがこの考案を限定するものではない。(e) Embodiment This invention will be explained by way of an embodiment shown in FIG. 1, but this invention is not limited to this invention.
第1図における検体分注器1は、内部液吸引ノ
ズル2、検体ノズル3、切換バルブ4、プランジ
ヤポンプ5及びプランジヤポンプを作動させるパ
ルスモータ6、及び制御器7とで構成され、8は
検体Sの入つた検体カツプ、9は反応管である。 The sample dispenser 1 in FIG. 1 is composed of an internal liquid suction nozzle 2, a sample nozzle 3, a switching valve 4, a plunger pump 5, a pulse motor 6 that operates the plunger pump, and a controller 7, and 8 is a sample pipette. A sample cup containing S, 9 is a reaction tube.
初期状態の検体分注器1は内部液が内部液吸引
ノズル2と検体ノズル内に満たされている。切替
えバルブ3のbを閉じてaとcを開きプランジヤ
ポンプ5によつて検体ノズル3で検体カツプ8内
の検体Sの規定量を吸引する。次いでプランジヤ
ポンプ5によつて、検体が反応管9に必要量づつ
吐出注入され分析に供される。分析が終了したな
らば、プランジヤポンプ5で残つた検体を押出し
て排棄して、検体ノズル3と内部液ノズル2を内
部液で満たしておく。 In the initial state of the sample dispenser 1, the internal liquid suction nozzle 2 and the sample nozzle are filled with internal liquid. Close b of the switching valve 3, open a and c, and use the plunger pump 5 to aspirate a specified amount of the sample S in the sample cup 8 through the sample nozzle 3. Next, the plunger pump 5 discharges and injects the required amount of the specimen into the reaction tube 9 for analysis. When the analysis is completed, the remaining sample is pushed out and discarded using the plunger pump 5, and the sample nozzle 3 and internal liquid nozzle 2 are filled with internal liquid.
また制御器7は上記作動を行う制御手段を具備
するとともに、第2図に示すごとく必要検体量A
の設定手段11、必要検体量に乗ずる定数Kの設
定手段12、一定検体量Bの設定手段13及びこ
れら手段からの信号によつて吸引検体量〔A(1
+K)+B〕を演算てこの検体量を吸引させるべ
くプランジヤポンプ5を作動するパルスモーター
6に出力する演算手段14を具備し、前記A(1
+K)+Bの量の検体を吸引吐出することができ
る。すなわち、まず必要検体量A例えば15μ1を
その設定手段11で設定し、必要検体量に乗ずる
定数K例えば0.5をその設定手段12で設定し、
一定検体量B例えば10μmをその設定手段13で
設定すると、演算手段14はこれらの各設定手段
からの信号を受けて吸引検体量〔A(1+K)+
B,すなわち15(1+0.5)+10=32.5μ1〕を演算
しこの検体量を吸引させるべき信号をプランジヤ
ポンプ5のパルスモータ6に出力し32.5μ1の検体
が吸引され、次いで反応管9に必要量づつ注入さ
れ分析に供される。 Further, the controller 7 is equipped with a control means for performing the above operations, and also has a required sample amount A as shown in FIG.
setting means 11 for setting a constant K by which the required sample amount is multiplied, a setting means 12 for setting a constant sample amount B, and signals from these means to determine the amount of aspirated sample [A(1
+K)+B] is provided with a calculation means 14 which outputs the result to the pulse motor 6 which operates the plunger pump 5 to aspirate the amount of sample using the lever.
+K)+B amount of specimen can be aspirated and discharged. That is, first, a required sample amount A, for example, 15μ1 is set by the setting means 11, a constant K, for example 0.5, by which the required sample amount is multiplied is set by the setting means 12,
When a constant sample amount B, for example 10 μm, is set by the setting means 13, the calculation means 14 receives signals from each of these setting means and calculates the aspirated sample amount [A(1+K)+
B, that is, 15 (1 + 0.5) + 10 = 32.5μ1], and outputs a signal to the pulse motor 6 of the plunger pump 5 to aspirate this amount of sample, and 32.5μ1 of the sample is aspirated, and then the amount of sample required for the reaction tube 9 is aspirated. It is injected in small quantities and subjected to analysis.
上記装置は適切なKとBの数値を選択して設定
することによつて内部液による検体の希釈の影響
を小さくするのに必要かつ余剰量を吸引採取し、
必要量づつ反応管に注入することができる。 By selecting and setting appropriate K and B values, the above device aspirates the necessary and surplus amount to reduce the influence of dilution of the specimen by internal fluid,
The required amount can be injected into the reaction tube.
(ハ) 効果
この考案の装置によれば検体必要量に対応し
て、内部液による検体の希釈の影響を小さくする
のに必要で充分な余剰量を吸引採取し必要量づつ
を反応管に注入することができる。(c) Effects According to the device of this invention, in response to the required amount of specimen, a sufficient surplus amount necessary and sufficient to reduce the influence of dilution of the specimen by the internal solution is collected by suction, and the required amount is injected into the reaction tube one by one. can do.
第1図はこの考案の装置の一実施例の構成説明
図、第2図はこの考案の一実施例の装置を作動さ
せる制御部の作動説明ブロツク図である。
1……検体分注器、2……内部液吸引ノズル、
3……検体ノズル、4……切換えバルブ、5……
プランジヤポンプ、6……パルスモータ、7……
制御器、8……検体カツプ、9……反応管、10
……必要検体量Aの設定手段、11……必要検体
量に乗ずる定数Kの設定手段、12……一定検体
量Bの設定手段、13……演算手段。
FIG. 1 is an explanatory diagram of the configuration of one embodiment of the device of this invention, and FIG. 2 is a block diagram illustrating the operation of a control section for operating the device of one embodiment of this invention. 1... Sample dispenser, 2... Internal liquid suction nozzle,
3...Sample nozzle, 4...Switching valve, 5...
Plunger pump, 6... Pulse motor, 7...
Controller, 8...Sample cup, 9...Reaction tube, 10
. . . Setting means for the required specimen amount A, 11 . . . Setting means for a constant K by which the required specimen amount is multiplied, 12 .
Claims (1)
行うための検体ノズル、切換手段によつて選択的
に前記内部液吸引ノズルもしくは前記検体ノズル
に連通されるプランジヤポンプ手段及びこれらの
手段の作動を制御する手段を少なくとも具備し、
この制御手段が必要検体量Aの設定手段、必要検
体量に乗ずる定数Kの設定手段、一定検定量Bの
設定手段、及びこれらの手段からの信号によつて
吸引検体量〔A(1+K)+B〕を演算してこの検
体量を吸引吐出させるべくプランジヤポンプ手段
に作動信号を出力する演算手段を具備することを
特徴とする検体分注器。[Claims for Utility Model Registration] An internal liquid suction nozzle, a specimen nozzle for suctioning and discharging a liquid sample, and a plunger pump selectively communicated with the internal liquid suction nozzle or the specimen nozzle by a switching means. comprising at least means and means for controlling the operation of these means;
This control means includes a means for setting the required sample amount A, a means for setting a constant K by which the required sample amount is multiplied, a means for setting a constant assay amount B, and a means for setting the aspirated sample amount [A(1+K)+B] by signals from these means. A sample dispenser comprising a calculation means for calculating the amount of the sample and outputting an operating signal to the plunger pump means for aspirating and discharging the amount of the sample.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6380484U JPS60176158U (en) | 1984-04-28 | 1984-04-28 | sample dispenser |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP6380484U JPS60176158U (en) | 1984-04-28 | 1984-04-28 | sample dispenser |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS60176158U JPS60176158U (en) | 1985-11-21 |
JPH0424433Y2 true JPH0424433Y2 (en) | 1992-06-09 |
Family
ID=30594297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP6380484U Granted JPS60176158U (en) | 1984-04-28 | 1984-04-28 | sample dispenser |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS60176158U (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2874030B2 (en) * | 1990-02-26 | 1999-03-24 | 三井化学株式会社 | Powder weighing device |
JP3866754B2 (en) * | 2005-12-26 | 2007-01-10 | 株式会社東芝 | Automatic analyzer |
JP2023183502A (en) * | 2022-06-16 | 2023-12-28 | 株式会社日立ハイテク | Automatic analysis device |
-
1984
- 1984-04-28 JP JP6380484U patent/JPS60176158U/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS60176158U (en) | 1985-11-21 |
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