JPH04166040A - Feed additive for fish farming and feed for fish framing - Google Patents

Feed additive for fish farming and feed for fish framing

Info

Publication number
JPH04166040A
JPH04166040A JP2124153A JP12415390A JPH04166040A JP H04166040 A JPH04166040 A JP H04166040A JP 2124153 A JP2124153 A JP 2124153A JP 12415390 A JP12415390 A JP 12415390A JP H04166040 A JPH04166040 A JP H04166040A
Authority
JP
Japan
Prior art keywords
fish
feed
extract
additive
licorice
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2124153A
Other languages
Japanese (ja)
Inventor
Takeshi Watanabe
武 渡辺
Tatsuo Aizawa
會澤 辰男
Nobuhiro Otake
大嶽 信弘
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maruzen Kasei Co Ltd
Original Assignee
Maruzen Kasei Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Maruzen Kasei Co Ltd filed Critical Maruzen Kasei Co Ltd
Priority to JP2124153A priority Critical patent/JPH04166040A/en
Publication of JPH04166040A publication Critical patent/JPH04166040A/en
Pending legal-status Critical Current

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  • Feed For Specific Animals (AREA)
  • Fodder In General (AREA)

Abstract

PURPOSE:To obtain the title additive for promoting growth of fishes in culture and improving feed efficiency, shortening a culture period, reducing culture cost, comprising an extract of root of Glycyrrhiza glabra containing a hydrophobia flavonoid. CONSTITUTION:Root of Glycyrrhiza glabra containing a hydrophobic flavonoid (e.g. retrochalcone or flavanone) is extracted with an organic solvent such as methylene chloride, methanol, acetone or ethyl acetate to give the objective additive.

Description

【発明の詳細な説明】 〔産業上の利用分野〕 本発明は、養殖魚の成長促進、飼料効率の改善等に有効
な養魚用飼料添加物および該飼料添加物を添加してなる
養魚用飼料に関するものである。
[Detailed Description of the Invention] [Field of Industrial Application] The present invention relates to a fish feed additive that is effective for promoting the growth of farmed fish, improving feed efficiency, etc., and a fish feed prepared by adding the feed additive. It is something.

〔従来の技術〕[Conventional technology]

近年、経済成長に伴い国民の食生活の多様化、高級化指
向が進んだ結果、食用魚においても低級魚から高級魚へ
の需要移行が生し、そのため、天然魚の漁獲だけに依存
していたのでは側底需要に応じきれない魚が出てきた。
In recent years, as a result of economic growth, people's dietary habits have become more diversified and people are becoming more sophisticated.As a result, there has been a shift in demand for edible fish from low-grade fish to high-grade fish, and as a result, there has been a shift in demand from low-grade fish to high-grade fish. Therefore, some fish were unable to meet the demand for the lateral bottom.

このような事情を背景に、食用魚類の増養殖は年々盛ん
になり、その量、魚種ともに著しく増加している。
Against this background, the cultivation of edible fish is becoming more popular year by year, and both the amount and species of fish are increasing markedly.

魚類の養殖が盛んになるにつれて、それに必要な飼料の
研究開発も急速に進展し、魚類の栄養要求量、発育促進
や飼料の利用効率、経済性等を考慮した種々の飼料が考
えられ、実用化されている。しかしながら、従来の養魚
用飼料は、高栄養価、高カロリーで投与には便利である
が高価なわりには発育成績および飼料効率等の点で必ず
しも満足できるものではないことが多く、養殖コスト低
減のために一層の改善を望まれている。
As fish farming has become more popular, research and development of the feed necessary for it has progressed rapidly, and various feeds have been developed that take into account the nutritional requirements of fish, growth promotion, feed utilization efficiency, economic efficiency, etc., and are now in practical use. has been made into However, conventional fish feeds are high in nutritional value, high in calories, and convenient to administer, but despite being expensive, they are often not always satisfactory in terms of growth performance and feed efficiency. Therefore, further improvements are desired.

〔発明が解決しようとする課題〕[Problem to be solved by the invention]

そこで本発明は、魚類養殖における魚体の成長促進と飼
料効率の一層の向上を可能にし、それにより魚類養殖に
おけるコストの低減を可能にしようとするものである。
SUMMARY OF THE INVENTION Accordingly, the present invention aims to make it possible to promote the growth of fish and further improve feed efficiency in fish farming, thereby making it possible to reduce costs in fish farming.

〔課題を解決するための手段〕[Means to solve the problem]

上記目的を達成する手段として本発明は、疎水性7ラボ
ノイド類を含有する甘草抽出物からなる養魚用飼料添加
物、および疎水性フラボノイド類を含有する甘草抽出物
を添加してなる養魚用飼料を提供する。
As a means to achieve the above object, the present invention provides a fish feed additive comprising a licorice extract containing hydrophobic 7-vonoids, and a fish feed comprising a licorice extract containing hydrophobic flavonoids. provide.

甘草中に含まれている疎水性フラボノイド類とじては、
レトロカルコン、フラバノン、フラボン、7ラボノール
、インフラボン、インフラバノン、ブチロカルパン、ク
メスタン、3−アリルクマリン、クマロン、インフラベ
ン、イソフラバン等、40種以上が確認されており、こ
れらはほとんどが甘草に特有の成分である。
Hydrophobic flavonoids contained in licorice include:
More than 40 species have been identified, including retrochalcones, flavanones, flavones, 7-ravonols, infravones, infravanones, butylocarpanes, coumestanes, 3-allylcoumarins, coumarons, infrabens, and isoflavans, and most of these are unique to licorice. It is an ingredient.

これら特徴的な疎水性7ラボノイド類を含有する甘草抽
出物は、養魚用飼料に配合して魚類に摂取させると、そ
の作用機構は定かでないが、顕著に成育を促進し、飼料
効率を向上させる。
When licorice extract containing these characteristic hydrophobic 7-labonoids is added to fish feed and ingested by fish, it significantly promotes growth and improves feed efficiency, although the mechanism of action is unclear. .

甘草の疎水性フラボノイドは、甘草またはその水抽出残
渣を疎水性フラボノイド類抽出能を有する有機溶媒で加
熱下に抽出処理することにより得られる。使用可能な抽
出溶媒の例としては、塩化メチレン、クロロホルム等の
ハロゲン化炭化水素、メタノール、エタノール等の低級
アルコール、アセトン等の低級脂肪酸、ケ)・ン、ジオ
キサン、エチルエーテル等の低級脂肪族エーテル、it
[エチル、酢酸n−プロピル等の低級脂肪族エステルが
あり、これらの外にも、ヘキサン10部(容量部)とア
セトン1〜4部の混合液や、ヘキサン10部とエチルア
ルコール0.5〜1.5部の混合液などは、好適な抽出
溶媒である。
Licorice hydrophobic flavonoids can be obtained by extracting licorice or its water-extracted residue with an organic solvent capable of extracting hydrophobic flavonoids under heating. Examples of extraction solvents that can be used include halogenated hydrocarbons such as methylene chloride and chloroform, lower alcohols such as methanol and ethanol, lower fatty acids such as acetone, and lower aliphatic ethers such as dioxane, ethyl ether, etc. , it
[There are lower aliphatic esters such as ethyl and n-propyl acetate, and in addition to these, there are also mixtures of 10 parts (by volume) hexane and 1 to 4 parts of acetone, and 10 parts of hexane and 0.5 to 0.5 to ethyl alcohol. A mixture such as 1.5 parts is a suitable extraction solvent.

得られる抽出物は、特有の臭気を有する黄色ないし褐色
の固体またはペースト状物質である。その中のフラボノ
イド類の種類および量は、抽出原料、抽出溶媒等により
若干異なるが、養魚用飼料添加物としての効用には大差
がなく、いずれも使用可能である。
The resulting extract is a yellow to brown solid or pasty substance with a characteristic odor. The types and amounts of flavonoids among them vary slightly depending on the extraction raw material, extraction solvent, etc., but there is no major difference in effectiveness as feed additives for fish farming, and any of them can be used.

フラボノイド類を含有する抽出物はそのままで養魚用飼
料添加物としてもよいが、有機溶媒に溶かし、デキスト
リン、乳糖などを加えて均一に混合した後、溶媒留去、
乾燥および粉砕を行なって粉末状にすれば、飼料に混ぜ
易く、使い易いものとなる。脂肪酸エステル、トリグリ
セライド等、食品用乳化剤を用いて水中に分散させ、液
状ないしペースト状の製品としてもよい。
Extracts containing flavonoids can be used as feed additives for fish farming as they are, but they can be dissolved in an organic solvent, added with dextrin, lactose, etc., mixed uniformly, and then distilled off.
If it is dried and crushed into a powder, it can be easily mixed into feed and used. It may be dispersed in water using a food emulsifier such as a fatty acid ester or triglyceride to form a liquid or paste product.

疎水性フラボノイド類含有抽出物を飼料に配合する場合
は、上述のようにして他の飼料原料と混合し易くしてお
くと均一混合が容易であるが、外にも任意の方法を採用
することができる。飼料に対する疎水性フラボノイド類
の配合量は、その飼料を投与する魚類の種類や魚体サイ
ズ等を考慮して、フラボノイドとして約0.05〜10
重量%の範囲で選定することが望ましい。
When adding hydrophobic flavonoid-containing extracts to feed, uniform mixing is facilitated by making it easier to mix with other feed ingredients as described above, but any other method may also be used. I can do it. The amount of hydrophobic flavonoids added to the feed should be approximately 0.05 to 10% as flavonoids, taking into account the type of fish to which the feed is administered and the size of the fish.
It is desirable to select within the range of weight %.

〔実施例〕〔Example〕

製造実施例1 甘草(Glycyrrbiza glabra)の粉砕
物500gを3aの塩化メチレンとともに2時間、還流
下に加熱して疎水性フラボノイド類を抽出した。抽出残
渣について同様の操作を繰り返し、合計110の抽出液
を得た。
Production Example 1 500 g of pulverized licorice (Glycyrrbiza glabra) was heated under reflux with 3a methylene chloride for 2 hours to extract hydrophobic flavonoids. The same operation was repeated for the extraction residue to obtain a total of 110 extracts.

この後、抽出液の溶媒を留去し、さらに減圧乾燥して、
淡褐色の抽出物13gを得た。この抽出物10gをエタ
ノール500m1に溶解し、増量剤としてデキストリン
90gを加えて均一に混合した後、溶媒を留去し、さら
に減圧乾燥して、粉末状の製剤を得た。
After that, the solvent of the extract was distilled off, and the extract was further dried under reduced pressure.
13 g of light brown extract was obtained. 10 g of this extract was dissolved in 500 ml of ethanol, 90 g of dextrin was added as a bulking agent and mixed uniformly, the solvent was distilled off, and the mixture was further dried under reduced pressure to obtain a powdered preparation.

この製剤は、原料甘草が含むフラボノイドの中でも代表
的なものであるグラブリジン(インフラパン)を0.9
%含有するものであった。
This preparation contains 0.9% of glabridin (infrapan), a typical flavonoid contained in the raw material licorice.
%.

製造実施例2 甘草(Glycyrrhiza 1nflala)の根
部1 kgを1%アンモニア水lOQに浸漬して加温下
に水溶性成分を抽出した後、抽出残渣を乾燥し、これを
アセトン511と=4− ともに2時間、還流下に加熱して疎水性フラボノイド類
を抽出した。抽出残渣について同様の操作を繰返し、合
計13flの抽出液を得た。この後、抽出液の溶媒を留
去し、さらに減圧乾燥して、淡褐色の抽出物46gを得
た。この抽出物40gをグリセリンオレイン酸エステル
・サンソフl−0−30(太陽化学株式会社製品)36
0gに溶解して、液状の製剤を得た。
Production Example 2 1 kg of the root of licorice (Glycyrrhiza 1nflala) was immersed in 1% ammonia water lOQ to extract the water-soluble components under heating.The extraction residue was dried, and this was mixed with acetone 511 and =4- Hydrophobic flavonoids were extracted by heating under reflux for 2 hours. The same operation was repeated for the extraction residue to obtain a total of 13 fl of the extract. Thereafter, the solvent of the extract was distilled off, and the extract was further dried under reduced pressure to obtain 46 g of a pale brown extract. Add 40g of this extract to glycerin oleate ester Sansofl-0-30 (Taiyo Kagaku Co., Ltd. product) 36
A liquid preparation was obtained by dissolving in 0 g.

この製剤は、原料甘草が含むフラボノイドの中でも代表
的なものであるリコカルコンA(イソフラバン)を1,
8%含有するものであった。
This preparation contains 1,000 ml of licochalcone A (isoflavan), which is a typical flavonoid contained in the raw material licorice.
It contained 8%.

試験例 同−母集団から無作為に取り出したラダ4l才魚を各区
65匹、2mX 2mX 2mの網止けす(設置場所:
長崎県;水温16.1〜21.5°C)に収容し、11
月〜12月の57日間(給餌日数39日間)、試験に供
した。
Test Example Same - 65 Ladder 4L year old fish randomly taken out from the population in each section, 2m x 2m x 2m net cage (installation location:
Nagasaki Prefecture; water temperature 16.1-21.5°C), 11
The test was conducted for 57 days (feeding days: 39 days) from March to December.

飼料としては日清製粉株式会社製ハマチモイストと冷凍
イワシを重量比1:1で混合し、これに前記実施例1の
甘草抽出物製剤を下記の所定量添加し、モイストペレッ
トとした。
As feed, Hamachi Moist (manufactured by Nisshin Seifun Co., Ltd.) and frozen sardines were mixed at a weight ratio of 1:1, and the following predetermined amount of the licorice extract preparation of Example 1 was added thereto to form moist pellets.

試験区 甘草抽出物製剤添加量 対照区    0 試験区1    t、05g/kg飼料試験区2  1
.8 ノ! 試験区3  10.8// 得られた甘草抽出物製剤添加飼料は直ちに冷凍して一2
0℃で保存し、使用当日に解凍して給餌した。
Test group Licorice extract preparation control group 0 Test group 1 T, 05g/kg feed test group 2 1
.. 8 No! Test Group 3 10.8// The obtained licorice extract preparation supplemented feed was immediately frozen and
The animals were stored at 0°C, thawed and fed on the day of use.

給餌は1日1回とし、飽食する量を与えた。試験結果を
表1に示す。
Feeding was carried out once a day, and the amount was fed to satiety. The test results are shown in Table 1.

表1:飼育結果 (注) 体重:30匹について測定した平均体重。試験開始時の
平均体重は259.0±38.4g0 日間給餌率−(給餌量)/(中間時給体重)×(飼育日
数or給餌日数)中間時給体重=(開始時総体重+終了
時総体重+取上げ体重)/2括弧内数字は給餌日数当た
りの日間給餌率増重率−(増重量)/(開始時総体重)
増重量−(終了時総体重+取上げ体重)−(開始時総体
重)飼料効率−(増重量)/(給餌量) 増肉係数−(給餌量)/(増重量) 〔発明の効果〕 試験例の結果から明らかなように、疎水性フラボノイド
を含有する甘草抽出物を飼料に配合して魚類に摂取させ
るようにした本発明によれば、魚類養殖における成長促
進と飼料効率の向上が可能になり、養殖期間の短縮と養
殖コストの低減が達成される。
Table 1: Breeding results (Note) Body weight: Average weight measured for 30 animals. Average body weight at the start of the test was 259.0±38.4g0 Daily feeding rate - (feeding amount) / (mid-term fed weight) x (breeding days or feeding days) mid-term fed weight = (total weight at start + total body weight at end) + Pick up weight) / 2 Numbers in parentheses are daily feeding rate weight gain rate per feeding days - (weight gain) / (total starting weight)
Weight gain - (Total weight at end + Weight taken up) - (Total weight at start) Feed efficiency - (Weight gain) / (Feeding amount) Meat gain coefficient - (Feeding amount) / (Weight gain) [Effects of the invention] Test As is clear from the results of the examples, according to the present invention, in which licorice extract containing hydrophobic flavonoids is added to feed and ingested by fish, it is possible to promote growth and improve feed efficiency in fish farming. As a result, the cultivation period and cultivation cost are reduced.

Claims (2)

【特許請求の範囲】[Claims] (1)疎水性フラボノイド類を含有する甘草抽出物から
なる養魚用飼料添加物。
(1) A fish feed additive consisting of a licorice extract containing hydrophobic flavonoids.
(2)疎水性フラボノイド類を含有する甘草抽出物を添
加してなる養魚用飼料。
(2) A fish feed containing a licorice extract containing hydrophobic flavonoids.
JP2124153A 1990-05-16 1990-05-16 Feed additive for fish farming and feed for fish framing Pending JPH04166040A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2124153A JPH04166040A (en) 1990-05-16 1990-05-16 Feed additive for fish farming and feed for fish framing

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2124153A JPH04166040A (en) 1990-05-16 1990-05-16 Feed additive for fish farming and feed for fish framing

Publications (1)

Publication Number Publication Date
JPH04166040A true JPH04166040A (en) 1992-06-11

Family

ID=14878254

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2124153A Pending JPH04166040A (en) 1990-05-16 1990-05-16 Feed additive for fish farming and feed for fish framing

Country Status (1)

Country Link
JP (1) JPH04166040A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007031A1 (en) * 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Benzene derivatives and immunopotentiating compositions or drug-sensitivity restoring agents containing the same
JP2009221148A (en) * 2008-03-17 2009-10-01 Maruzen Pharmaceut Co Ltd Immunoactivator and immunoactivation feed for fish
CN103431210A (en) * 2013-07-29 2013-12-11 中国水产科学研究院南海水产研究所 Prawn feed additive and application thereof

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001007031A1 (en) * 1999-07-26 2001-02-01 Shionogi & Co., Ltd. Benzene derivatives and immunopotentiating compositions or drug-sensitivity restoring agents containing the same
JP2009221148A (en) * 2008-03-17 2009-10-01 Maruzen Pharmaceut Co Ltd Immunoactivator and immunoactivation feed for fish
CN103431210A (en) * 2013-07-29 2013-12-11 中国水产科学研究院南海水产研究所 Prawn feed additive and application thereof

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