JPH0399004A - Skin cosmetic - Google Patents

Abstract

PURPOSE:To obtain a skin cosmetic imparting springiness and moist feeling to the skin, free from stickiness, slimy feeling and stretching feeling and having excellent protective effect by compounding a water-soluble partially deacetylated chitin having specific average molecular weight and deacetylation ratio. CONSTITUTION:The objective skin cosmetic is produced by compounding 0.01-10wt.% (preferably 0.05-5wt.%) of a water-soluble partially deacetylated chitin having an average molecular weight of 100,000-1,000,000 and a deacetylation ratio of 40-60% [the compound of formula ((m) is ratio of N- acetyl-D-glucosamine residue to total residues and is 0.4-0. 6)]. The compound of formula has excellent adsorptivity to the skin and film-forming property, gives good feeling to the skin when compounded to a cosmetic and forms a cosmetic having extremely excellent skinprotecting effect. The compound of formula can be produced by hydrolyzing natural chitin with an aqueous solution of an alkali metal hydroxide of 5-50% concentration in homogeneous system at <=50 deg.C.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Application Field] The present invention provides water-soluble partially deacetylated chitin with an average molecular weight of 100,000 to 1,000,000 and a deacetylation rate of 40 to 60%.
01 to 10% by weight of the skin cosmetic. This product is a skin cosmetic that gives a firm and moist feeling to the skin and has an excellent skin protection effect. [Prior art and its problems] Normally, skin and hair are covered with sebum secreted by themselves, but when washed with soap or detergent, etc.
Sebum is removed more than necessary, and the skin and hair lose moisture after washing, leaving them with a dry, hard feel. In order to solve these problems, various compounds are added to cleaning compositions as wetting agents. Compounds used for this purpose include squalane, oils such as jojoba oil, glycerin, 1,3-butylene glycol,
Polyhydric alcohols such as various sugars, salts such as amino acid salts, pyrrolidone carboxylates, and lactates, hyaluronic acid, sodium chondroitin sulfate, hydrolysates of collagen, keratin, and gelatin, and polymeric compounds such as polyethylene glycol. Extracts from natural products such as bovine placenta extract, aloe extract, loofah extract, lecithin, etc. are used. However, oils such as squalane and jojoba oil, glycerin,
■ When using polyhydric alcohols such as 3-butylene glycol and various sugars, salts such as amino acid salts, pyrrolidone carboxylates, and lactates, the skin may remain sticky or slimy, and hyaluronic acid, sodium chondroitin sulfate, etc. ,
When using polymeric compounds such as collagen, keratin and gelatin hydrolysates, and polyethylene glycol, skin cosmetics leave a feeling of tightness or sliminess on the skin, making it difficult to obtain skin cosmetics with a satisfactory feel. That is the current situation. [Problems of the present invention] An object of the present invention is to obtain a skin cosmetic that gives a supple and moist feeling to the skin, is free from stickiness, sliminess, and tightness, has an excellent feeling of use, and has an excellent protective effect on the skin. [Means for Solving the Problems] In view of the above circumstances, the present inventors have conducted intensive research on the feel of skin cosmetics, their moisturizing effects, etc., in order to overcome the problems of the prior art. As a result of stacking, the average molecular weight is 10
Skin cosmetics containing 0.01 to 10% by weight of water-soluble partially deacetylated chitin with a deacetylation rate of 40 to 60% at 10,000 to 1,000,000 give the skin a supple and moist feeling, and are not sticky. It was discovered that the product has no slimy or tight feeling and has an excellent feeling of use and an excellent skin protection effect, and based on this knowledge, the present invention was completed. That is, the present invention relates to a skin cosmetic containing 0.01 to 10% by weight of water-soluble partially deacetylated chitin with an average molecular weight of 100,000 to 1,000,000 and a deacetylation rate of 40 to 60%. The configuration of the present invention will be explained in detail below. The water-soluble partially deacetylated chitin with a deacetylation rate of 40 to 60% used in the present invention is represented by the general formula (A). (in is the ratio of N-acetyl-D-glucosamine residues to the total number of residues) (A) The water-soluble partially deacetylated chitin is, for example,
It is obtained by the method disclosed in Japanese Patent No. 47479, and the average molecular weight and deacetylation rate can be controlled by appropriately setting the reaction temperature and reaction time. This method is a method in which naturally produced chitin is homogeneously alkaline hydrolyzed in an aqueous alkali metal hydroxide solution with a concentration of 5 to 50% at a temperature of 50°C or less. Average molecular weight 100,000 to 1
Water-soluble partially deacetylated chitin with a deacetylation rate of 40 to 60% at 1,000,000 ml has excellent adsorption to the skin, film form, and ability, and when added to skin cosmetics, it leaves a supple and moist feeling on the skin. The result is a product that provides excellent skin protection and provides a pleasant feeling of use, with no stickiness, sliminess, or tightness. If the average molecular weight of the partially deacetylated chitin is less than 100,000, excellent moisturizing and protective effects on the skin cannot be obtained, and if it is more than 1 million, the skin becomes stiff and the feeling of use is poor. Further, if the deacetylation rate is less than 40% or more than 60%, the solubility in water decreases significantly and is impractical. The hair cosmetic of the present invention can take any form such as a solution, emulsion, paste-like mixture, or powder. Also,
The hair cosmetics of the present invention can be used as facial cleansing creams, facial cleansing foams, cleansing creams, cleansing milk, cleansing lotions, massage creams, cold creams, moisture creams, milky lotions, lotions, packs, aftershave creams, sunscreen creams, Such as tanning oil. The amount of water-soluble partially deacetylated chitin in the skin cosmetics of the present invention varies depending on the purpose, but is usually 0.01
-10% by weight, preferably 0.05-5% by weight.
If the blending amount is 0.01% by weight, the effect of water-soluble partially deacetylated chitin will not appear, and if it exceeds 10% by weight, the feeling of use as a cosmetic will be poor, making it impractical. ．． In addition to the above-described water-soluble partially deacetylated chitin, the skin cosmetics of the present invention may contain appropriate amounts of other ingredients commonly used in cosmetics, as needed. Examples of known components used here include, for example, the oil phase includes millet wax, wood wax, spermaceti wax, carnauba wax, candilar wax, cacao butter, cetyl alcohol, stearyl alcohol, oleal alcohol, Oleic acid, linoleic acid, stearic acid, lanolin, olive oil, camellia oil, avocado oil, coconut oil,
Animal and vegetable oils such as jojoba oil, macadamia nut oil, cottonseed oil, castor oil, coconut oil, grapeseed oil, oleic acid, oleyl alcohol, and squalane, and minerals such as solid paraffin, ceresin, microcrystalline wax, petrolatum, liquid paraffin, and silicone oil. oils and fats,
and isobrobyl myristate, isoprobyl palmitate, cetyl 2-ethylhexanoate, 2-octyldodecyl myristate, inoctylic acid triglyceride, oleyl oleate, isostearic acid, octyldodecanol, hexyldecanol, polyether, etc. Examples include oils and fats. In addition, the water phase components include glycerin, ethylene glycol, propylene glycol, diethylene glycol, dipropylene glycol, triethylene glycol, diglycerin, polyglycerin, glycerin EO adduct, glycerin PO adduct, 1,3-butylene glycol,
Polyhydric alcohols such as 1,4-butylene glycol, polyethylene glycol, polypropylene glycol, polyvinylpyrrolidone, quince seed gum, tranguum gum, alginate, vectin, carboxymethylcellulose, hyaluronic acid, polyvinyl alcohol, cationized cellulose, protein hydration Decomposition products, water-soluble polymers such as fatty acid polypeptide condensates, sugar alcohols such as sorbitol, xylitol, maltitose, mannitol, and their EO. PO adduct, ascorbic acid, citric acid,
Gluconic acid, succinic acid, acetic acid, oxalic acid, tartaric acid, lactic acid, edetic acid, pyrrolidone carboxylate, various amino acids and other organic acids and their salts, other ethyl alcohol, isobrobanol, urea, phosphoric acid and its salts etc. Examples of surfactants that can be used include polyoxyethylene fatty acid partial ester, polyoxyethylene sorbitan fatty acid partial ester, polyoxyethylene glycene fatty acid partial ester, polyglycerin fatty acid partial ester, fatty acid alkanolamide, fatty acid alkanolamide. Ethylene oxide adducts, polyoxyethylene glycerin fatty acids, biroglutamic acid monoglycerin esters, acylglutamic acid glycerin esters and other nonionic surfactants, alkyl sulfates, polyoxyethylene alkyl sulfates, fatty acid amide ether sulfates, alkylbenzene snorephonates, anoles. Quinoleoxysnolephate, sulfur succinic acid higher alcohol ester salt, N long chain fatty acid acyl-N
- Methyl taurine salt, fatty acid salt, N-long chain acyl glutamate, N-long chain acyl sarcosine salt, anionic active agent such as monoalkyl phosphate, carboxybetaine type, imidazoline type, lecithin, aminosulfonic acid type, alkyl Examples include amine oxide type, amphoteric activators such as NεNε-dimethyl or NεNε, Nε-trimethyl-Nα-acyl basic amino acids, and cationic activators such as dialkyldimethylammonium chloride, alkyltrimethylammonium chloride, fatty acid acyl arginine ester salts. Powder components include inorganic powders such as talc, kaolin, titanium dioxide, titanium-coated mica, mica, iron oxide, silicic acid, ultramarine, Shaoqing, zinc white, clay, precipitated calcium carbonate, bismuth oxychloride, bentonite, and montmorillonite. Examples include organic powders such as N-monolong chain acyl basic amino acids, guanine, and laminate resin pearl agents. Furthermore, these cosmetic compositions contain commonly used cosmetic auxiliaries such as thickeners, softeners, wetting agents, supergreasing agents, emollients, wetting agents, preservatives, antifoaming agents, chelating agents, and protective colloids. It can contain agents, UV absorbers, whitening agents, drugs, fragrances, colorants, or any other ingredients commonly used in cosmetics. [Example] Next, the present invention will be explained in more detail by showing Examples and Comparative Examples. However, the present invention is not limited to this. The evaluation of the product effects in the L Q Example and Comparative Example of "LQ" is as follows. A panel of 20 (years old, 17-45 years old, 4 men, 16 women) evaluated each item on a five-point scale. The score was 5 points if the feel was favorable, 4 points if it was somewhat favorable, 3 points if it was fair, 2 points if it was slightly unfavorable, and 1 point if it was unfavorable. The average of the 5-level ratings was calculated and the results were displayed as shown below. ◎: 4.5-5.0 0: 3.5-4.4 Δ: 2.5-3.4 X: 1. 5-2.4 XX: 1. 0~1.4 The following three items were evaluated: ■ Skin firmness, ■ Moist feeling, and ■ Lack of stickiness, sliminess, and tightness. Each sample of 1L constant partially deacetylated chitin on the L side was heated to 5, 0, 1.
0, 0.5, 0. 2, 0. ．． A test solution was prepared by dissolving it in a 0.25% acetic acid aqueous solution to a concentration of 1 mg/mu. For each of these test solutions, 20, 30, 40, 45, 60, 90, 120, 13
5. Light scattering was measured at an angle of 150°, and the weight average molecular weight was determined using ZimmP10t.
Examples 1-3 Comparative Examples 1-3 Two-layer skin lotions were manufactured using the formulations shown in Table 1 and according to the following manufacturing method. Component C was mixed and dissolved, component B was added, and the mixture was heated and melted at 80°C.To this, component A, which had been heated and melted at 80°C, was gradually added while stirring, and the mixture was heated to 30°C. The resulting two-layer skin lotion was evaluated and
The results are shown in the lower part of Table 1. Compared to the comparative examples, the examples showed less firmness, moisturizing, and stickiness and sliminess of the skin.
The lack of tightness has improved. Example 4 Cleansing Foam Removal (A) Monosalium N-Lauroyl-Glutamate 33. O N-stearoyl monosodium L-glutamate 2.
Ol, 3-butylene glycol 20. 0
Sodium pyrrolidone carboxylate (50%) 5.0 Methylparaben 0.1 (B) Ethylene glycol distear-1.1. 0 Weight% Weight% Weight% Weight% Weight% Weight% Weight% POE (60) Glyceryl monostearate 1. O Weight % Coconut oil fatty acid diethanolamide 8. 0% by weight (C
) 50% partially deacetylated chitin (molecular weight 200,000> 1.0 wt% lactic acid
0. 1 wt% POE (40
) Hydrogenated castor oil monopyroglutamate monoisostearate 3. O wt% purified water
The remaining amount of Component C was mixed and dissolved, Component A was added, and the mixture was stirred and dissolved at 75 to 80°C. Component B, which had been previously heated to 80°C and dissolved, was added to this while stirring. While stirring, the mixture was cooled to 35°C to obtain a cleansing foam. This product gave a firm and moist feeling to the skin and was easy to use. Example 5 Cleansing foam removal (A) Monosodium N-lauroyl-glutamate 22. O N-stearoyl monosodium L-glutamate 3.
OPEG400 16. 0 Glycerin 8. 0 polyethylene glycol distearate 1.5 N-coconut oil fatty acid acyl arginine ethyl ester pyrrolidone carboxylate 1. 0(B) Polyethylene glycol monostearate 4.5 40% partially deacetylated chitin (molecular weight 500,000> 0.5 Weight% Weight% Weight% Lactic acid 0.05% Purified water
After stirring and dissolving the remaining amount of 4 ingredients B, add Kaibun A and bring to a boiling point of 70 to 80.
Mix and dissolve at ℃. A cleansing foam was obtained by cooling while stirring. This product gives the skin a firm and moist feeling, and makes it slimy.
It was not sticky or tight and had an excellent feeling of use. Weight% Weight% Weight% Weight% Weight% Cleansing Lotion Example 6 Nobuo (A) Cetyl stearate alcohol Vaseline Liquid paraffin silicone oil (B) Fragrance (C) 60% partially deacetylated chitin (molecular weight 150,000) Lactic acid POE ( 20) Oleyl ether POE (20) Sorbitan monolaurate ester methyl paraben ethyl alcohol appropriate amount O. 0. 1. O. O. 3. Weight 95 Weight % Weight % Weight % Weight % Weight % 01 Weight % 2 5 Weight % 5 Weight % 1 Weight % O Weight % Propylene glycol 5. Offli
% blended wetting agent “Prodew 100J*1 3.0
After mixing and dissolving Component C with the remaining amount of purified water by weight, it was heated to 70°C, and Component A, which had been heated and dissolved in advance at 70°C, was gradually added while stirring.
The mixture was sufficiently emulsified with a homogenizer, cooled to 40°C while stirring, and component B was added to obtain a cleansing lotion. This product gives the skin a firm and moist feeling, and makes it slimy.
There was no stickiness or tightness, and it felt good after use. Example 7 Spooning (A> Solid paraffin microcrystalline wax Beeswax Petrolatum jelly Liquid paraffin Grapeseed oil Sorbitan sesquioleate (B) Ethyl paraben Methyl paraben Tocopherol acetate Soap powder (C) 50% partially deacetylated chitin (molecular weight 200,000 ) W/O type massage clit 4. 6. 3. 1 0. 4 0. 3. 3. 0. Mu O Weight% Weight% Weight% Weight% Weight% Weight% 5 Weight% Weight% Weight% Weight% Weight% 5% by weight Pyrrolidone carboxylic acid 0.1% by weight P
・OE (20) Sorbitan monooleate 0. 5 Heavy M9≦Purified water Dissolve the remaining amount of Component C, heat to 70°C, and add Component B.
I stirred it. Component A dissolved in this in advance at 70℃
was added and pre-emulsified, then uniformly emulsified with a Bomo mixer and cooled to obtain a W/O type massage cream. This product gives the skin a firm and moist feeling, and makes it slimy.
There was no stickiness or tightness, and I was impressed with the feeling of use. Example 8 0/W type moisturizer number 1 (A) Cetyl alcohol squalane stearate beeswax vaseline POE (25) Cetyl ether glyceryl monostearate butyl paraben (B) Fragrance (C) Glycerin PEG400 Glycyrrhizinate ammonium salt cream weight 25% by weight Weight% Weight% Weight% 2. 0% by weight 1. 0. 5 Weight% 1 Weight% Appropriate amount 5. 2. 30% by weight 0% by weight O. 1% by weight Allantoin 0. 1 ffi amount% collagen hydrolyzate 0. 2 wt% methylparaben 0.2 wt% (D) 60% partially deacetylated chitin (molecular weight 150,000> 0.2 wt% lactic acid
0.04jl volume% purified water
The remaining amount of D was dissolved, and Component C was added and dissolved by heating at 75°C. Component A, which had been heated and dissolved in advance at 75°C, was added to this and preliminarily stirred. Emulsify with a homogenizer, cool to 40°C, add component B, stir and cool to obtain an O/W type moisture cream. This product gave a firm and moist feeling to the skin, and was not slimy, sticky, or tight, and had an excellent feeling of use. Example 9 Emulsion 1 (A) Cetyl stearate Alcohol Beeswax POE (10) Monooleic acid ester (B) Flavor Quince seed extract (5%) Ethyl alcohol (C) Propylene glycol Urocanic acid 50% partial deacetylation Chitin (molecular weight 200,000) Citric acid purified water 1.5 wt% 0.5 wt% 2.0 wt% 1. O wt% appropriate amount 2 0.3, 0 wt% 0.5 wt% 5. 0.2' JLN% 05% by weight O. Remaining amount O 0% by weight % by weight ``L method precipitate C'' was mixed and dissolved and heated to 70°C.To this, component A, which had been heated and dissolved at 70°C, was added for pre-emulsification and homogeneous. It was emulsified uniformly with a mixer. It was cooled while stirring, and component B was added at 50°C, and the emulsion was cooled to 30°C to obtain a milky lotion. This product gave a moist feeling to the skin and was slimy.
It was not sticky or tight and had an excellent feeling of use. Example 10 Toner lotion remover (A) POE (15) Oleyl ether urocanic acid ethyl methyl paraben fragrance Ethyl alcohol (B) Glycerin pyrrolidone carboxylic acid pyrrolidone sodium carboxylate Allantoin 50% partially deacetylated chitin (molecular weight 200,000 > Mix and dissolve 4 parts of purified water and Component B at room temperature, 1.0 0.1 0.1 Appropriate amount 10. 1% by weight 1% by weight 0.1% by weight Remaining amount Component A mixed and dissolved at room temperature was added to this while stirring, and filtered {to obtain a lotion. This product has a firmness on the skin. Gives a moist feeling, slimy,
There was no stickiness or tightness, and I loved the feeling of using it. Example 11 Back rolling (A) Ethyl alcohol 8. 0% by weight Methylparaben 0. 1 Weight% Fragrance Appropriate amount (B) Polyvinyl alcohol 10.0 Weight% PEG
4000 0.4 Weight% Glycerin 3.0 Weight% 50% Partially Deacetylated Chitin <Molecular JL 200,000> 1.0 Weight% Milk i! ! 0
．． 2% by weight Purified water Remaining amount Component B was mixed and dissolved, then heated to 80°C, and component A, which had been mixed and dissolved in advance, was added thereto. A pack was obtained by cooling to room temperature. This product gave a firm and moist feeling to the skin and was easy to use. Example 12 Emulsified foundation supervisor (A) Stearin @ 0. 4 Weight%
N-monohydrogenated beef tallow fatty acid acyl-L-glutamine i! 12 0. 3 wt% isoprobyl myristate 4.0 wt% squalane 12.0 wt% ethyl urocanate 0. 5 wt% POE (10) stearyl ether 1.5 wt% POE
(40) Hydrogenated castor oil pyroglutamic acid isostearic acid diester 0.5% by weight Cetyl alcohol 0. 3 Heavy tan% (B) Mica 14. O Weight % (C) 40% partially deacetylated chitin powder 0. 5 weight% milk M
O. 02% by weight (D) Talc 5. O weight%
Red red 2.5% by weight Red 2
No. 02 0. 5% by weight (E) Methylparaben 0.09% by weight Triethanolamine 0. 4 Weight % propylene glycol 5. O wt% purified water
52.19% by weight (F) Fragrance 0. 3 Weight%1
Theft (1) Component C was added to 50 times the volume of purified water and stirred to dissolve. After adding component B and stirring to disperse, the water was concentrated to dryness to obtain a partially deacetylated chitin-coated powder. (2> After mixing and dissolving component A at 90°C, we added Kaibun D and the partially deacetylated chitin-coated miyuki obtained in (1) and uniformly dispersed. (3) Mixed and dissolved Kabun E. After heating to 90°C, it was added to (2). (4) The 191 tank was cooled, and Kaibun F was added at 40°C.
The mixture was further cooled and made uniform, and then filled into containers to obtain an emulsified foundation. I obtained a foundation that spreads lightly, has a smooth feel, and has long-lasting moisture. It also had excellent color and morphological stability. Example 13 Formulation (A) Cetyl alcohol squaran stearate N-myristoyl-L-monoglutamic acid monostearate POE (20) Sorbitan N-lauroyl-L-glutamic acid POE (5) Octyl dodecyl ether diester (B) Glycerin 60% partial removal Acetylated chitin citrate urocanic acid base cream 2 6. O. 3. 2. 2. 1. 9. 1. O. 0. O weight% 0 weight% O weight% 0 weight% 4 weight% 6 weight% O weight% O 5 5 weight% weight% weight% Ethylparaben 0. 2% by weight Purified water 53.3% by weight (C) Fragrance 0. 5% by weight A was heated to 75°C and mixed in a homomixer.
Component B at 75°C was added to this and emulsified. The mixture was cooled while stirring, and when the temperature reached 30'C, component C was added to prepare the product. A base cream that spreads lightly, has a smooth feel, and has long-lasting moisture was obtained. It also had excellent color and morphological stability. Nail enamel Example 14 Nail technology (A) Nitrocellulose alkyd resin Acetyl tributyl citrate di-camphor Organic bentonite Isopropanol Ethyl acetate Butyl acetate Butyl alcohol Toluene (B) 40% partially deacetylated chitin Red No. 213 1 0. 0% by weight 9. 0 Weight% Weight% Weight% Weight% Weight% Weight% Weight% Weight% Weight% 1. O weight% 5. O Weight % Gloss a8 Component A was uniformly mixed and dissolved. Component B, which had been mixed uniformly in advance, was added to this, mixed uniformly, and filled into a container to obtain a product. The obtained foil enamel had excellent elongation and adhesion. [Effects of the Invention] The skin cosmetic of the present invention provides a supple and moist feeling to the skin, is free from stickiness, sliminess, and tightness, and has an excellent usability and protective effect on the skin, and its commercial value is extremely high.

Claims (1)

[Claims] Average molecular weight 100,000 to 1 million, deacetylation rate 40 to 6
0% water-soluble partially deacetylated chitin from 0.01 to 10
A skin cosmetic characterized by containing % by weight of