JPH038355B2 - - Google Patents

Info

Publication number
JPH038355B2
JPH038355B2 JP56006247A JP624781A JPH038355B2 JP H038355 B2 JPH038355 B2 JP H038355B2 JP 56006247 A JP56006247 A JP 56006247A JP 624781 A JP624781 A JP 624781A JP H038355 B2 JPH038355 B2 JP H038355B2
Authority
JP
Japan
Prior art keywords
triamterene
adduct
aldehyde
adducts
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP56006247A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56118082A (en
Inventor
Higuchi Takeru
Shii Baaman Anando
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPS56118082A publication Critical patent/JPS56118082A/ja
Publication of JPH038355B2 publication Critical patent/JPH038355B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Inorganic Insulating Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
JP624781A 1980-01-18 1981-01-19 Aldehyde adduct of novel 2*4*77triaminoo66phenylbutelidine Granted JPS56118082A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/113,313 US4285947A (en) 1980-01-18 1980-01-18 Aldehyde adducts of triamterene

Publications (2)

Publication Number Publication Date
JPS56118082A JPS56118082A (en) 1981-09-16
JPH038355B2 true JPH038355B2 (enExample) 1991-02-05

Family

ID=22348739

Family Applications (1)

Application Number Title Priority Date Filing Date
JP624781A Granted JPS56118082A (en) 1980-01-18 1981-01-19 Aldehyde adduct of novel 2*4*77triaminoo66phenylbutelidine

Country Status (10)

Country Link
US (1) US4285947A (enExample)
EP (1) EP0032725B1 (enExample)
JP (1) JPS56118082A (enExample)
AT (1) ATE13184T1 (enExample)
DE (1) DE3170356D1 (enExample)
DK (1) DK19181A (enExample)
ES (1) ES498602A0 (enExample)
GR (1) GR73158B (enExample)
IE (1) IE50808B1 (enExample)
PT (1) PT72362B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51421B1 (en) 1980-08-01 1986-12-24 Smith & Nephew Ass Ophthalmic compositions containing triamterene
US4425346A (en) 1980-08-01 1984-01-10 Smith And Nephew Associated Companies Limited Pharmaceutical compositions
US4526777A (en) * 1983-01-06 1985-07-02 Mylan Pharmaceuticals Inc. Pharmaceutical combination composition and associated method
US4547498A (en) * 1983-01-06 1985-10-15 Mylan Pharmaceuticals Inc. Pharmaceutical combination composition and associated method
DE3407695A1 (de) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt Pteridinverbindungen mit pharmazeutischer wirksamkeit
US4804540A (en) * 1987-12-16 1989-02-14 G. D. Searle & Co. Process for preparing the combination products of triamterene and hydrochlorothiazide
US4981852A (en) * 1988-05-13 1991-01-01 Multilan Ag Chemical compounds triamterene and hydrochlorothiazide
US11690825B2 (en) 2016-03-09 2023-07-04 Board Of Regents, The University Of Texas System 20-HETE receptor (GPR75) antagonists and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127403A (en) * 1964-03-31 G-alkyl-z
US3081230A (en) * 1960-09-08 1963-03-12 Smith Kline French Lab Diuretic and antihypertensive triaminoarylpteridines
US3534140A (en) * 1968-08-14 1970-10-13 Us Army Triamino arylpteridines as an antifibrillatory agent

Also Published As

Publication number Publication date
PT72362B (en) 1984-10-09
ATE13184T1 (de) 1985-05-15
DE3170356D1 (en) 1985-06-13
IE50808B1 (en) 1986-07-23
EP0032725A1 (en) 1981-07-29
GR73158B (enExample) 1984-02-13
PT72362A (en) 1981-02-01
ES8201162A1 (es) 1981-12-01
EP0032725B1 (en) 1985-05-08
JPS56118082A (en) 1981-09-16
IE810049L (en) 1981-07-18
ES498602A0 (es) 1981-12-01
US4285947A (en) 1981-08-25
DK19181A (da) 1981-07-19

Similar Documents

Publication Publication Date Title
KR950014238B1 (ko) 퀴놀론카복실산 유도체로 피복된 이온교환수지, 이의 제조방법 및 이의 용도
US4581363A (en) Furo-(3,4-C)-pyridine derivatives and therapeutic compositions containing the same
JPH05246992A (ja) １−ヒドロキシピリド−２−オン、又はその塩から成る、患者の体内にある毒性レベルの金属を減少させるのに有効な医薬組成物
US3917837A (en) Method of using trans-2-(6-amino-9H-purin-9-yl)-cyclopentanol
JPH038355B2 (enExample)
US4767758A (en) Pharmaceutical compositions containing thiophene compounds, and new thiophene compounds
AU599034B2 (en) Furosemide salts
NL7905956A (nl) Nieuwe imidazochinoxalinen en zouten daarvan, werkwijze voor hun bereiding, hun toepassing als geneesmiddelen en farmaceutische preparaten, die deze verbindingen bevatten.
EP0178261A2 (en) Substituted 2-furanyl or 5-oxo-2-furanyl-alkoxy phosphoryl alkyl cyclimmonium salts
US4406893A (en) N-Alkoxycarbonyl-N'-[2-nitro-4 or 5-alkylthiophenyl]-N"-[substituted alkyl]-guanidines useful as anthelmintics
US5149697A (en) Cobalt porphyrin pharmaceutical compositions
US4562203A (en) Rifamycins derivatives and preparation and pharmaceutical compositions thereof
JPH0262878A (ja) 新規なベンゾフロキノリン誘導体
JPH085863B2 (ja) １４−アニソイルアコニンおよびそれを有効成分とする新規な鎮痛・抗炎症剤
EP0131787A2 (en) Novel Schiff bases of (aminoalkyl or substituted aminoalkyl)-amino-9,10-anthracenediones
US4228177A (en) 2,3-Dihydro-3-(1H-imidazol-1-ylmethylene)-4H-1-benzothiopyran-4-ones
US4119643A (en) 4-Amino-6-nitro derivatives of 2H-3,4-dihydrobenzo[b]pyrans
US4320135A (en) Inhibiting growth hormone secretion with 5,5-substituted hydantoin derivatives
US4329355A (en) Mesoionic antitumor compositions and methods for using the same in the treatment of cancer
US4255573A (en) Imidazoindole derivatives and pharmaceutical compositions comprising imidazoindole derivatives
US4250174A (en) 3-Substituted imidazo [1,2-A] pyridines
CN115038701A (zh) Jak抑制剂的晶型及其应用
RU2049091C1 (ru) Производные 4-оксо-1,4-дигидропиримидина, обладающие антиаллергической активностью
EP0140492B1 (en) L-arginine isoxicamate
AT383806B (de) Verfahren zur herstellung neuer verbindungen von furo-(3,4-c)-pyridinderivaten und von deren salzen