GR73158B - - Google Patents

Info

Publication number
GR73158B
GR73158B GR63870A GR810163870A GR73158B GR 73158 B GR73158 B GR 73158B GR 63870 A GR63870 A GR 63870A GR 810163870 A GR810163870 A GR 810163870A GR 73158 B GR73158 B GR 73158B
Authority
GR
Greece
Prior art keywords
triamterene
adducts
novel
bioavailability
compared
Prior art date
Application number
GR63870A
Other languages
Greek (el)
English (en)
Inventor
Takeru Higvchi
Anand C Burman
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of GR73158B publication Critical patent/GR73158B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D475/00—Heterocyclic compounds containing pteridine ring systems
    • C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Inorganic Insulating Materials (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
GR63870A 1980-01-18 1981-01-15 GR73158B (enExample)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/113,313 US4285947A (en) 1980-01-18 1980-01-18 Aldehyde adducts of triamterene

Publications (1)

Publication Number Publication Date
GR73158B true GR73158B (enExample) 1984-02-13

Family

ID=22348739

Family Applications (1)

Application Number Title Priority Date Filing Date
GR63870A GR73158B (enExample) 1980-01-18 1981-01-15

Country Status (10)

Country Link
US (1) US4285947A (enExample)
EP (1) EP0032725B1 (enExample)
JP (1) JPS56118082A (enExample)
AT (1) ATE13184T1 (enExample)
DE (1) DE3170356D1 (enExample)
DK (1) DK19181A (enExample)
ES (1) ES498602A0 (enExample)
GR (1) GR73158B (enExample)
IE (1) IE50808B1 (enExample)
PT (1) PT72362B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE51421B1 (en) 1980-08-01 1986-12-24 Smith & Nephew Ass Ophthalmic compositions containing triamterene
US4425346A (en) 1980-08-01 1984-01-10 Smith And Nephew Associated Companies Limited Pharmaceutical compositions
US4526777A (en) * 1983-01-06 1985-07-02 Mylan Pharmaceuticals Inc. Pharmaceutical combination composition and associated method
US4547498A (en) * 1983-01-06 1985-10-15 Mylan Pharmaceuticals Inc. Pharmaceutical combination composition and associated method
DE3407695A1 (de) * 1984-03-02 1985-09-12 Röhm Pharma GmbH, 6108 Weiterstadt Pteridinverbindungen mit pharmazeutischer wirksamkeit
US4804540A (en) * 1987-12-16 1989-02-14 G. D. Searle & Co. Process for preparing the combination products of triamterene and hydrochlorothiazide
US4981852A (en) * 1988-05-13 1991-01-01 Multilan Ag Chemical compounds triamterene and hydrochlorothiazide
US11690825B2 (en) 2016-03-09 2023-07-04 Board Of Regents, The University Of Texas System 20-HETE receptor (GPR75) antagonists and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3127403A (en) * 1964-03-31 G-alkyl-z
US3081230A (en) * 1960-09-08 1963-03-12 Smith Kline French Lab Diuretic and antihypertensive triaminoarylpteridines
US3534140A (en) * 1968-08-14 1970-10-13 Us Army Triamino arylpteridines as an antifibrillatory agent

Also Published As

Publication number Publication date
PT72362B (en) 1984-10-09
ATE13184T1 (de) 1985-05-15
DE3170356D1 (en) 1985-06-13
IE50808B1 (en) 1986-07-23
EP0032725A1 (en) 1981-07-29
PT72362A (en) 1981-02-01
ES8201162A1 (es) 1981-12-01
EP0032725B1 (en) 1985-05-08
JPS56118082A (en) 1981-09-16
JPH038355B2 (enExample) 1991-02-05
IE810049L (en) 1981-07-18
ES498602A0 (es) 1981-12-01
US4285947A (en) 1981-08-25
DK19181A (da) 1981-07-19

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