JPH0360506B2 - - Google Patents

Info

Publication number

JPH0360506B2

JPH0360506B2 JP62208967A JP20896787A JPH0360506B2 JP H0360506 B2 JPH0360506 B2 JP H0360506B2 JP 62208967 A JP62208967 A JP 62208967A JP 20896787 A JP20896787 A JP 20896787A JP H0360506 B2 JPH0360506 B2 JP H0360506B2

Authority

JP

Japan

Prior art keywords

blood

passage

membrane oxygenator

membrane

oxygenator

Prior art date

1987-08-22

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired - Lifetime

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• 239000008280 blood Substances 0.000 claims description 378
• 210000004369 blood Anatomy 0.000 claims description 378
• 239000012528 membrane Substances 0.000 claims description 206
• 230000017531 blood circulation Effects 0.000 claims description 35
• 210000004072 lung Anatomy 0.000 claims description 8
• 239000007789 gas Substances 0.000 description 36
• 239000012510 hollow fiber Substances 0.000 description 33
• CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 16
• 230000010412 perfusion Effects 0.000 description 16
• 238000005192 partition Methods 0.000 description 15
• 229910002092 carbon dioxide Inorganic materials 0.000 description 8
• 239000001569 carbon dioxide Substances 0.000 description 8
• 239000006260 foam Substances 0.000 description 8
• -1 polypropylene Polymers 0.000 description 8
• QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 6
• 230000000052 comparative effect Effects 0.000 description 6
• 229910052760 oxygen Inorganic materials 0.000 description 6
• 239000001301 oxygen Substances 0.000 description 6
• 239000004743 Polypropylene Substances 0.000 description 4
• 230000004087 circulation Effects 0.000 description 4
• 238000002474 experimental method Methods 0.000 description 4
• 239000000463 material Substances 0.000 description 4
• 229920001155 polypropylene Polymers 0.000 description 4
• 239000012780 transparent material Substances 0.000 description 4
• 230000005484 gravity Effects 0.000 description 3
• 230000002209 hydrophobic effect Effects 0.000 description 3
• 238000000034 method Methods 0.000 description 3
• 238000006213 oxygenation reaction Methods 0.000 description 3
• 239000011148 porous material Substances 0.000 description 3
• 229920005989 resin Polymers 0.000 description 3
• 239000011347 resin Substances 0.000 description 3
• 241000283690 Bos taurus Species 0.000 description 2
• 239000004698 Polyethylene Substances 0.000 description 2
• PPBRXRYQALVLMV-UHFFFAOYSA-N Styrene Chemical compound C=CC1=CC=CC=C1 PPBRXRYQALVLMV-UHFFFAOYSA-N 0.000 description 2
• BZHJMEDXRYGGRV-UHFFFAOYSA-N Vinyl chloride Chemical compound ClC=C BZHJMEDXRYGGRV-UHFFFAOYSA-N 0.000 description 2
• 239000000853 adhesive Substances 0.000 description 2
• 230000001070 adhesive effect Effects 0.000 description 2
• 230000000903 blocking effect Effects 0.000 description 2
• 229920002301 cellulose acetate Polymers 0.000 description 2
• 238000010586 diagram Methods 0.000 description 2
• 229920002492 poly(sulfone) Polymers 0.000 description 2
• 229920002239 polyacrylonitrile Polymers 0.000 description 2
• 239000004417 polycarbonate Substances 0.000 description 2
• 229920000515 polycarbonate Polymers 0.000 description 2
• 229920000573 polyethylene Polymers 0.000 description 2
• 229920001343 polytetrafluoroethylene Polymers 0.000 description 2
• 239000004810 polytetrafluoroethylene Substances 0.000 description 2
• 239000004814 polyurethane Substances 0.000 description 2
• 238000000926 separation method Methods 0.000 description 2
• 239000007779 soft material Substances 0.000 description 2
• BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
• MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
• 206010018910 Haemolysis Diseases 0.000 description 1
• 241000220317 Rosa Species 0.000 description 1
• XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 description 1
• 230000023555 blood coagulation Effects 0.000 description 1
• 230000036770 blood supply Effects 0.000 description 1
• 239000003795 chemical substances by application Substances 0.000 description 1
• 238000004925 denaturation Methods 0.000 description 1
• 230000036425 denaturation Effects 0.000 description 1
• 238000009792 diffusion process Methods 0.000 description 1
• 229910001882 dioxygen Inorganic materials 0.000 description 1
• 230000000694 effects Effects 0.000 description 1
• 238000005534 hematocrit Methods 0.000 description 1
• 230000008588 hemolysis Effects 0.000 description 1
• 229920001600 hydrophobic polymer Polymers 0.000 description 1
• 239000007788 liquid Substances 0.000 description 1
• 239000007791 liquid phase Substances 0.000 description 1
• 238000005191 phase separation Methods 0.000 description 1
• 239000002504 physiological saline solution Substances 0.000 description 1
• 239000002861 polymer material Substances 0.000 description 1
• 229920005672 polyolefin resin Polymers 0.000 description 1
• 229920002635 polyurethane Polymers 0.000 description 1
• 229920003225 polyurethane elastomer Polymers 0.000 description 1
• 238000004382 potting Methods 0.000 description 1
• 102000004169 proteins and genes Human genes 0.000 description 1
• 108090000623 proteins and genes Proteins 0.000 description 1
• 229910052710 silicon Inorganic materials 0.000 description 1
• 239000010703 silicon Substances 0.000 description 1
• 229920002379 silicone rubber Polymers 0.000 description 1
• 239000004945 silicone rubber Substances 0.000 description 1
• 238000003466 welding Methods 0.000 description 1