JPH0345076B2 - - Google Patents
Info
- Publication number
- JPH0345076B2 JPH0345076B2 JP57006084A JP608482A JPH0345076B2 JP H0345076 B2 JPH0345076 B2 JP H0345076B2 JP 57006084 A JP57006084 A JP 57006084A JP 608482 A JP608482 A JP 608482A JP H0345076 B2 JPH0345076 B2 JP H0345076B2
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- chroman
- spiro
- imidazolidine
- dione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 208000024891 symptom Diseases 0.000 claims description 14
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- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 claims description 12
- 230000001684 chronic effect Effects 0.000 claims description 12
- KMPWYEUPVWOPIM-UHFFFAOYSA-N cinchonidine Natural products C1=CC=C2C(C(C3N4CCC(C(C4)C=C)C3)O)=CC=NC2=C1 KMPWYEUPVWOPIM-UHFFFAOYSA-N 0.000 claims description 12
- KMPWYEUPVWOPIM-KODHJQJWSA-N cinchonidine Chemical compound C1=CC=C2C([C@H]([C@H]3[N@]4CC[C@H]([C@H](C4)C=C)C3)O)=CC=NC2=C1 KMPWYEUPVWOPIM-KODHJQJWSA-N 0.000 claims description 11
- 238000004519 manufacturing process Methods 0.000 claims description 7
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- LFNSMJIWORQTOV-UHFFFAOYSA-N 6-chloro-2-methylspiro[2,3-dihydrochromene-4,5'-imidazolidine]-2',4'-dione Chemical compound C12=CC(Cl)=CC=C2OC(C)CC21NC(=O)NC2=O LFNSMJIWORQTOV-UHFFFAOYSA-N 0.000 description 5
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- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 4
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- RPAIBTVEPAACRP-UHFFFAOYSA-N 6-fluoro-2-methyl-2,3-dihydrochromen-4-one Chemical compound FC1=CC=C2OC(C)CC(=O)C2=C1 RPAIBTVEPAACRP-UHFFFAOYSA-N 0.000 description 3
- ATRRKUHOCOJYRX-UHFFFAOYSA-N Ammonium bicarbonate Chemical compound [NH4+].OC([O-])=O ATRRKUHOCOJYRX-UHFFFAOYSA-N 0.000 description 3
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Landscapes
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP608482A JPS58124788A (ja) | 1982-01-20 | 1982-01-20 | 光学活性ヒダントイン誘導体，その製造方法ならびにそれを含有する治療用薬剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP608482A JPS58124788A (ja) | 1982-01-20 | 1982-01-20 | 光学活性ヒダントイン誘導体，その製造方法ならびにそれを含有する治療用薬剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58124788A JPS58124788A (ja) | 1983-07-25 |
| JPH0345076B2 true JPH0345076B2 (pt) | 1991-07-09 |
Family
ID=11628672
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP608482A Granted JPS58124788A (ja) | 1982-01-20 | 1982-01-20 | 光学活性ヒダントイン誘導体，その製造方法ならびにそれを含有する治療用薬剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58124788A (pt) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE96668T1 (de) * | 1989-02-22 | 1993-11-15 | Sanwa Kagaku Kenkyusho Co | Pharmazeutische zusammensetzung, die ein hydantoin-derivat enthaelt. |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53144575A (en) * | 1977-05-23 | 1978-12-15 | Pfizer | Spiroohydantoin |
| JPS56152483A (en) * | 1980-03-28 | 1981-11-26 | Pfizer | Novel manufacture of polarizable hydantoins |
-
1982
- 1982-01-20 JP JP608482A patent/JPS58124788A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53144575A (en) * | 1977-05-23 | 1978-12-15 | Pfizer | Spiroohydantoin |
| JPS56152483A (en) * | 1980-03-28 | 1981-11-26 | Pfizer | Novel manufacture of polarizable hydantoins |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58124788A (ja) | 1983-07-25 |
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