JPH0331199B2 - - Google Patents

Info

Publication number
JPH0331199B2
JPH0331199B2 JP59154184A JP15418484A JPH0331199B2 JP H0331199 B2 JPH0331199 B2 JP H0331199B2 JP 59154184 A JP59154184 A JP 59154184A JP 15418484 A JP15418484 A JP 15418484A JP H0331199 B2 JPH0331199 B2 JP H0331199B2
Authority
JP
Japan
Prior art keywords
endo
octane
epoxy
exo
structural formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59154184A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6042382A (ja
Inventor
Berunareji Birugirio
Bonifuachio Fuausuto
Marugutsuchi Roberuto
Fuaano Maurichio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BEREASU SpA
Original Assignee
BEREASU SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BEREASU SpA filed Critical BEREASU SpA
Publication of JPS6042382A publication Critical patent/JPS6042382A/ja
Publication of JPH0331199B2 publication Critical patent/JPH0331199B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP59154184A 1983-07-26 1984-07-26 エンド−８，８−ジアルキル−８−アゾニアビシクロ〔３．２．１〕オクタン−６，７−エキソ−エポキシ−３−アルキルカルボキシレ−ト塩、それ等の製造方法、およびそれ等を活性要素として含む治療用組成物 Granted JPS6042382A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT22238/83A IT1194343B (it) 1983-07-26 1983-07-26 Sali di endo-8,8-dialchil-8-azoniabiciclo (3.2.1) ottan-6,7-esso-epossi-3-alchilcarbossilati,processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo
IT22238A/83 1983-07-26

Publications (2)

Publication Number Publication Date
JPS6042382A JPS6042382A (ja) 1985-03-06
JPH0331199B2 true JPH0331199B2 (OSRAM) 1991-05-02

Family

ID=11193504

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59154184A Granted JPS6042382A (ja) 1983-07-26 1984-07-26 エンド−８，８−ジアルキル−８−アゾニアビシクロ〔３．２．１〕オクタン−６，７−エキソ−エポキシ−３−アルキルカルボキシレ−ト塩、それ等の製造方法、およびそれ等を活性要素として含む治療用組成物

Country Status (11)

Country Link
US (1) US4558054A (OSRAM)
EP (1) EP0133218B1 (OSRAM)
JP (1) JPS6042382A (OSRAM)
AT (1) ATE38989T1 (OSRAM)
AU (1) AU562763B2 (OSRAM)
CA (1) CA1248956A (OSRAM)
DE (1) DE3475402D1 (OSRAM)
DK (1) DK162285C (OSRAM)
IT (1) IT1194343B (OSRAM)
NZ (1) NZ208857A (OSRAM)
ZA (1) ZA845308B (OSRAM)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1190133B (it) * 1986-06-19 1988-02-10 Chiesi Farma Spa Derivati di acido valproico e di acido (e)-2-valproenoico,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE4108393A1 (de) * 1991-03-15 1992-09-17 Boehringer Ingelheim Kg Neue ester bi- und tricyclischer aminoalkohole, ihre herstellung und ihre verwendung in arzneimitteln
US6706726B2 (en) * 2000-10-14 2004-03-16 Boehringer Ingelheim Pharma Gmbh & Co. Kg Anticholinergics which may be used as medicaments as well as processes for preparing them
PE20060826A1 (es) * 2004-12-06 2006-10-08 Smithkline Beecham Corp Derivado oleofinico de 8-azoniabiciclo[3.2.1]octano y combinacion farmaceutica que lo comprende

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2962499A (en) * 1957-07-03 1960-11-29 Endo Lab Certain esters of tropine and tropinium salts
DE1795818C2 (de) * 1966-01-26 1980-07-10 C.H. Boehringer Sohn, 6507 Ingelheim Quartärsalze des N-Äthylnorscopolamin
DE1670048C3 (de) * 1966-01-26 1980-09-04 C.H. Boehringer Sohn, 6507 Ingelheim Neue Norscopolaminderivate
GB1413484A (en) * 1972-04-18 1975-11-12 Angeli Inst Spa Scopolamine derivatives
IT1140998B (it) * 1980-06-18 1986-10-10 Valeas Ind Chimica E Farmaceut Sali di endo-8-metil-8-sin-alchil-8-azoniabiciclo aperta par. quadrata 3.2.1. chiusa par. quadrata-ottan-3-alchilcarbossilati, processo per la loro preparazione e composizioni terapeutiche che li contengono come principio attivo

Also Published As

Publication number Publication date
IT8322238A0 (it) 1983-07-26
EP0133218A2 (en) 1985-02-20
DK363284A (da) 1985-01-27
EP0133218A3 (en) 1986-12-30
DK162285C (da) 1992-03-02
JPS6042382A (ja) 1985-03-06
AU562763B2 (en) 1987-06-18
EP0133218B1 (en) 1988-11-30
ATE38989T1 (de) 1988-12-15
IT8322238A1 (it) 1985-01-26
AU3116384A (en) 1985-01-31
ZA845308B (en) 1985-02-27
DK162285B (da) 1991-10-07
DK363284D0 (da) 1984-07-25
IT1194343B (it) 1988-09-14
US4558054A (en) 1985-12-10
NZ208857A (en) 1988-05-30
DE3475402D1 (en) 1989-01-05
CA1248956A (en) 1989-01-17

Similar Documents

Publication Publication Date Title
US5543426A (en) Use of certain 3,7-disubstituted indole compounds for treating depression or cognitive disorders
GB2145416A (en) Benzoic acid derivatives
JPH05507071A (ja) 新規化合物
DE69009195T2 (de) Isoxazol-Derivate mit Anti-Serotonin-Aktivität, deren Herstellungsverfahren und diese enthaltende Zusammensetzungen.
HU200460B (en) Process for producing n-substituted benzamides and pharmaceutical compositions comprising same as active ingredient
EP0560604B1 (en) Cinnoline-3-carboxylic acid derivatives as 5-HT3 antagonists
JP3453394B2 (ja) ジヒドロベンゾフランカルボキサミド及びその製造方法
JPH0331199B2 (OSRAM)
PT99831A (pt) Processo para a preparacao de derivados de acido benzoico contendo uma cadeia lateral di-azaciclica ou azabiciclica
CH617197A5 (OSRAM)
US3351625A (en) Certain nortropanyl ethers of dibenzo [a, d]-1, 4-cycloheptadiene
US4507308A (en) Analgesically or anti-inflammatory effective 4-quinolyl anthranilic acid derivatives
JPH06510064A (ja) 置換イミダゾベンズオキサジン−１−オンの誘導体及び該誘導体の製造方法
EP0101633A1 (en) Pyridinecarboxylic esters of dopamine and of its N-alkyl derivatives
FR2694292A1 (fr) Dérivés de benzimidazole-2-thione-, leur préparation et leur application en tant que médicament.
US2958697A (en) Ethoxy benzoate esters
KR800000537B1 (ko) 아미노-페닐-에탄올아민의 제조방법
CS199265B2 (en) Process for preparing quarternary ammonium salts of n-dialkylaminoalkyl-n-/2-indanyl/anilines
CA1267898A (en) Substituted benzoic acid alkylene bridged piperidyl amides
KR810000583B1 (ko) 4a-아릴-옥타하이드로-1H-2-피린딘류의 제조방법
FI59089B (fi) Foerfarande foer framstaellning av 5-endobensoyloxi-n-(amino-(laegre)alkyl)bicyklo(2,2,1)heptan-2,3-di-endokarboxylsyraimider motverkande oregelbunden hjaertverksamhet
GB2111489A (en) N-isopropyl-noratropine-N- oxide
DK144821B (da) Analogifremgangsmaade til fremstilling af 4-heptamethylenimino-1-butyl-xanthen-9-carboxylat eller syreadditionssalte deraf
CH634050A5 (en) 3-Aminopropoxyindoles
JPH07304745A (ja) アダマンチルエチルカンフィジン誘導体およびその用途