JPH0329056B2 - - Google Patents

Info

Publication number
JPH0329056B2
JPH0329056B2 JP58070794A JP7079483A JPH0329056B2 JP H0329056 B2 JPH0329056 B2 JP H0329056B2 JP 58070794 A JP58070794 A JP 58070794A JP 7079483 A JP7079483 A JP 7079483A JP H0329056 B2 JPH0329056 B2 JP H0329056B2
Authority
JP
Japan
Prior art keywords
compound
trans
formula
reaction
mixture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58070794A
Other languages
English (en)
Japanese (ja)
Other versions
JPS59196839A (ja
Inventor
Atsusuke Terada
Shunji Naruto
Yoshio Iizuka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Priority to JP58070794A priority Critical patent/JPS59196839A/ja
Priority to US06/600,372 priority patent/US4595699A/en
Priority to DK201284A priority patent/DK162600C/da
Priority to ES531814A priority patent/ES531814A0/es
Priority to CA000452517A priority patent/CA1230127A/en
Priority to FI841594A priority patent/FI80014C/fi
Priority to EP84302705A priority patent/EP0123535B1/en
Priority to DE8484302705T priority patent/DE3460335D1/de
Publication of JPS59196839A publication Critical patent/JPS59196839A/ja
Priority to US06/798,236 priority patent/US4622421A/en
Publication of JPH0329056B2 publication Critical patent/JPH0329056B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/54—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings and other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58070794A 1983-04-21 1983-04-21 フエニル酢酸誘導体 Granted JPS59196839A (ja)

Priority Applications (9)

Application Number Priority Date Filing Date Title
JP58070794A JPS59196839A (ja) 1983-04-21 1983-04-21 フエニル酢酸誘導体
US06/600,372 US4595699A (en) 1983-04-21 1984-04-16 Immune system regulation using novel phenylalkanoic acid derivative
DK201284A DK162600C (da) 1983-04-21 1984-04-18 Oe4-(2-hydroxycyklohexylmethyl)phenylaaalkansyrederivater og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende disse
ES531814A ES531814A0 (es) 1983-04-21 1984-04-18 Procedimiento para la preparacion de nuevos derivados de acidos fenilalcanoicos.
FI841594A FI80014C (fi) 1983-04-21 1984-04-19 Foerfarande foer framstaellning av terapeutiskt anvaendbara (4-/(2-hydroxi-cyklohexyl)metyl/fenyl) -alkansyraderivat.
CA000452517A CA1230127A (en) 1983-04-21 1984-04-19 Phenylalkanoic acid derivatives, their preparation and use
EP84302705A EP0123535B1 (en) 1983-04-21 1984-04-19 New phenylalkanoic acid derivatives, their preparation and use
DE8484302705T DE3460335D1 (en) 1983-04-21 1984-04-19 New phenylalkanoic acid derivatives, their preparation and use
US06/798,236 US4622421A (en) 1983-04-21 1985-11-14 Phenylalkanoic acid derivatives and their use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58070794A JPS59196839A (ja) 1983-04-21 1983-04-21 フエニル酢酸誘導体

Publications (2)

Publication Number Publication Date
JPS59196839A JPS59196839A (ja) 1984-11-08
JPH0329056B2 true JPH0329056B2 (enExample) 1991-04-23

Family

ID=13441797

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58070794A Granted JPS59196839A (ja) 1983-04-21 1983-04-21 フエニル酢酸誘導体

Country Status (8)

Country Link
US (2) US4595699A (enExample)
EP (1) EP0123535B1 (enExample)
JP (1) JPS59196839A (enExample)
CA (1) CA1230127A (enExample)
DE (1) DE3460335D1 (enExample)
DK (1) DK162600C (enExample)
ES (1) ES531814A0 (enExample)
FI (1) FI80014C (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
FR2601670B1 (fr) * 1986-07-17 1988-10-07 Cird Nouveaux derives bicycliques aromatiques, leur procede de preparation et leur utilisation en medecine humaine et veterinaire et en cosmetique
US4748272A (en) * 1986-08-01 1988-05-31 Rorer Pharmaceutical Corp. Phenoxyphenylacetates for use as potential modulators of arichidonic acid pathways
US5179124A (en) * 1988-01-25 1993-01-12 University Of Iowa Research Foundation Anti-inflammatory for use in external and internal eye inflammations
US4968718A (en) * 1988-01-25 1990-11-06 University Of Iowa Research Foundation Topically effective, nonsteroidal drug for use in external and internal eye inflammations
EP0641760B1 (en) * 1991-08-10 1996-11-06 Hisamitsu Pharmaceutical Co., Inc. Phenylalkanoic acid derivative, production thereof, and separation of optical isomers thereof
AU2250097A (en) 1996-02-13 1997-09-02 G.D. Searle & Co. Compositions comprising a cyclooxygenase-2 inhibitor and a leukotriene b4 receptor antagonist
ES2169351T3 (es) 1996-02-13 2002-07-01 Searle & Co Combinaciones que tienen efectos inmunosupresores, que contienen inhibidores de ciclooxigenasa-2 y 5-lipoxigenasa.
JP2001506574A (ja) 1996-02-13 2001-05-22 ジー．ディー．サール アンド カンパニー シクロオキシゲナーゼ―２阻害剤およびロイコトリエンａ４ヒドロラーゼ阻害剤を含有する免疫抑制効果をもつ配合物
CA2495537C (en) 2000-08-29 2010-03-30 Nobex Corporation Immunoregulatory compounds and derivatives and methods of treating diseases therewith
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
EP1773767B1 (en) 2004-07-07 2016-03-09 Biocon Limited Synthesis of azo bonded immunoregulatory compounds
KR100906478B1 (ko) 2008-01-10 2009-07-08 강원대학교산학협력단 호모알렌일 알코올 유도체와 인듐을 이용한 이의 제조방법

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161538A (en) * 1977-04-05 1979-07-17 Sankyo Company Limited Substituted phenylacetic acid derivatives and process for the preparation thereof
JPS584699B2 (ja) * 1977-04-05 1983-01-27 三共株式会社 置換フエニル酢酸誘導体及びその製法
DD141422A5 (de) * 1978-01-27 1980-04-30 Schering Ag Verfahren zur herstellung von phenylessigsaeure-derivaten
DE2861078D1 (en) * 1978-07-21 1981-12-03 Schering Ag Indan-1-carboxylic acid derivatives,process for their preparation and pharmaceutical preparations containing these compounds
AT358018B (de) * 1978-07-28 1980-08-11 Sankyo Co Verfahren zur herstellung von neuen substituierten phenylessigsaeuren und deren nied. alkylestern und salzen
JPS57106617A (en) * 1980-12-23 1982-07-02 Sankyo Co Ltd Analgesic and anti-inflammatory agent

Also Published As

Publication number Publication date
ES8506575A1 (es) 1985-08-01
DK201284A (da) 1984-10-22
FI80014C (fi) 1990-04-10
CA1230127A (en) 1987-12-08
US4622421A (en) 1986-11-11
EP0123535A1 (en) 1984-10-31
FI841594L (fi) 1984-10-22
DK162600C (da) 1992-04-06
JPS59196839A (ja) 1984-11-08
DE3460335D1 (en) 1986-08-28
DK162600B (da) 1991-11-18
EP0123535B1 (en) 1986-07-23
US4595699A (en) 1986-06-17
FI841594A0 (fi) 1984-04-19
ES531814A0 (es) 1985-08-01
FI80014B (fi) 1989-12-29
DK201284D0 (da) 1984-04-18

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