JPH029800B2 - - Google Patents
Info
- Publication number
- JPH029800B2 JPH029800B2 JP9042582A JP9042582A JPH029800B2 JP H029800 B2 JPH029800 B2 JP H029800B2 JP 9042582 A JP9042582 A JP 9042582A JP 9042582 A JP9042582 A JP 9042582A JP H029800 B2 JPH029800 B2 JP H029800B2
- Authority
- JP
- Japan
- Prior art keywords
- peptide
- reaction
- trna synthetase
- amino acid
- acetonitrile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
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- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000002124 endocrine Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- QIGLJVBIRIXQRN-SSDOTTSWSA-N ethyl (2r)-2-amino-4-methylpentanoate Chemical compound CCOC(=O)[C@H](N)CC(C)C QIGLJVBIRIXQRN-SSDOTTSWSA-N 0.000 description 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 229960003692 gamma aminobutyric acid Drugs 0.000 description 1
- BTCSSZJGUNDROE-UHFFFAOYSA-N gamma-aminobutyric acid Chemical compound NCCCC(O)=O BTCSSZJGUNDROE-UHFFFAOYSA-N 0.000 description 1
- 238000005227 gel permeation chromatography Methods 0.000 description 1
- 229960002989 glutamic acid Drugs 0.000 description 1
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
- 229960002743 glutamine Drugs 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 229960002449 glycine Drugs 0.000 description 1
- HNDVDQJCIGZPNO-UHFFFAOYSA-N histidine Natural products OC(=O)C(N)CC1=CN=CN1 HNDVDQJCIGZPNO-UHFFFAOYSA-N 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229930195733 hydrocarbon Natural products 0.000 description 1
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 1
- 230000001077 hypotensive effect Effects 0.000 description 1
- 229960003646 lysine Drugs 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229940049920 malate Drugs 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N malic acid Chemical compound OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 229960004452 methionine Drugs 0.000 description 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 1
- 230000003132 peptidolytic effect Effects 0.000 description 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 description 1
- 239000008363 phosphate buffer Substances 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 238000001556 precipitation Methods 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 229960001153 serine Drugs 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 description 1
- 229960000553 somatostatin Drugs 0.000 description 1
- 238000010189 synthetic method Methods 0.000 description 1
- 239000011800 void material Substances 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9042582A JPS58209991A (ja) | 1982-05-27 | 1982-05-27 | ペプチド又はペプチド誘導体の合成法 |
| EP83300362A EP0086053B1 (de) | 1982-01-26 | 1983-01-25 | Verfahren zur Herstellung von Peptiden oder Peptide-Derivaten |
| DE8383300362T DE3361649D1 (en) | 1982-01-26 | 1983-01-25 | Process for synthesizing peptides or peptide derivatives |
| DK28283A DK28283A (da) | 1982-01-26 | 1983-01-25 | Fremgangsmaade til syntetisering af peptider eller peptidderivater |
| CA000420242A CA1194440A (en) | 1982-01-26 | 1983-01-26 | Process for synthesizing peptides or peptide derivatives |
| US06/461,307 US4572894A (en) | 1982-01-26 | 1983-01-26 | Process for synthesizing peptides or peptide derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9042582A JPS58209991A (ja) | 1982-05-27 | 1982-05-27 | ペプチド又はペプチド誘導体の合成法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58209991A JPS58209991A (ja) | 1983-12-07 |
| JPH029800B2 true JPH029800B2 (de) | 1990-03-05 |
Family
ID=13998246
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9042582A Granted JPS58209991A (ja) | 1982-01-26 | 1982-05-27 | ペプチド又はペプチド誘導体の合成法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58209991A (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH03187385A (ja) * | 1983-11-10 | 1991-08-15 | Meito Sangyo Kk | モノグリセライドの製造法 |
| JPS60244296A (ja) * | 1984-05-18 | 1985-12-04 | Unitika Ltd | α−アミノ酸アミドの製造方法 |
| CN100400660C (zh) | 2002-12-26 | 2008-07-09 | 协和发酵工业株式会社 | 生产二肽的方法 |
| DE602006010990D1 (de) | 2005-03-18 | 2010-01-21 | Kyowa Hakko Bio Co Ltd | Verfahren zur dipeptidherstellung |
-
1982
- 1982-05-27 JP JP9042582A patent/JPS58209991A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58209991A (ja) | 1983-12-07 |
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