JPH0264462A - Biochemical automatic analytical system - Google Patents
Biochemical automatic analytical systemInfo
- Publication number
- JPH0264462A JPH0264462A JP21498788A JP21498788A JPH0264462A JP H0264462 A JPH0264462 A JP H0264462A JP 21498788 A JP21498788 A JP 21498788A JP 21498788 A JP21498788 A JP 21498788A JP H0264462 A JPH0264462 A JP H0264462A
- Authority
- JP
- Japan
- Prior art keywords
- rack
- specimen
- sample container
- sample
- biochemical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000012742 biochemical analysis Methods 0.000 claims abstract description 8
- 238000000926 separation method Methods 0.000 claims abstract description 3
- 230000032258 transport Effects 0.000 claims description 18
- 238000005119 centrifugation Methods 0.000 claims description 7
- 239000006228 supernatant Substances 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 abstract description 4
- 239000000523 sample Substances 0.000 description 53
- 210000002966 serum Anatomy 0.000 description 7
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 238000012360 testing method Methods 0.000 description 5
- 238000010586 diagram Methods 0.000 description 4
- 230000000694 effects Effects 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
- 239000012472 biological sample Substances 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 208000006454 hepatitis Diseases 0.000 description 1
- 231100000283 hepatitis Toxicity 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 238000004904 shortening Methods 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
Landscapes
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
Description
【発明の詳細な説明】
〔産業上の利用分野〕
本発明は臨床検査における生体試料の生化学分析システ
ムに係り、特に安全かつ迅速な処理の行なえる生化学自
動分析システムに関する。DETAILED DESCRIPTION OF THE INVENTION [Field of Industrial Application] The present invention relates to a biochemical analysis system for biological samples in clinical tests, and particularly to an automatic biochemical analysis system that can perform safe and rapid processing.
臨床検査部門における即応性、迅速性の要求が最近富に
高まっている。これは緊急に検査を要する場合の他に、
被検者への即時報告による待時間の短縮によるサービス
向上などの必要からである。The demand for immediate response and speed in clinical testing departments has recently increased. This applies in addition to cases where inspection is urgently required.
This is due to the need to improve services by shortening waiting times through immediate reporting to patients.
臨床検査部門の生化学分野では、採血後の遠心分離、血
清の分注２分析装置による測定などの際。In the biochemistry field of the clinical laboratory department, during centrifugation after blood collection and measurement using a serum dispensing 2 analyzer.
これまでほとんど人手を介して作業を行なっていた。新
医療、１９８８年２月号 ｐ５５〜６０にその具体例が
示されている。Until now, most of the work had been done manually. A specific example is shown in Shin Medical, February 1988 issue, pages 55-60.
生化学分析において、検体の注入された容器（試験管、
真空採血管など）を血清分離のため遠心機に着脱する時
１分離された血清を分析装置用の試料容器ラックする場
合、この試料容器を分析装置の試料供給部へ乗せる場合
など、全て血液。In biochemical analysis, the container into which the specimen is injected (test tube,
When attaching and detaching a vacuum blood collection tube (e.g., vacuum blood collection tube) to a centrifuge for serum separation, when placing the separated serum in a sample container rack for an analyzer, and when loading this sample container onto the sample supply section of an analyzer, all blood is used.
血清の入った容器は、大部分が人間の手を介して運搬、
保持されており、最近特に問題になっているエイズ、肝
炎などの感染からの危険を防止する必要にせまられてい
る。又分注や分析装置へ試料容器を移す場合、容器に識
別用の符号が無い場合が多く、従って定められた順番に
容器をそろえておく必要があるが、不注意によりこの順
番を間違うと検体のとり違えとなって重大な誤診につな
がるおそれがあり、絶対に起こしてはならない問題であ
る。又検体がある数まとまって集荷され処理する場合は
作業が効率的に行なえるが、小量でしかも時間的に間隔
が空いて処理しなければならない場合、非能率的な作業
となる。Containers containing serum are mostly transported by humans,
There is an urgent need to prevent the dangers from infections such as AIDS and hepatitis, which have become a particular problem recently. Furthermore, when transferring sample containers to a dispensing or analyzing device, the containers often do not have identification codes, and therefore it is necessary to arrange the containers in a prescribed order. This is a problem that must never be allowed to occur, as it may lead to serious misdiagnosis. Furthermore, if a certain number of specimens are collected and processed in batches, the work can be carried out efficiently, but if the specimens have to be processed in small quantities at intervals of time, the work becomes inefficient.
本発明の目的は、これらの問題を解決することにある。The purpose of the present invention is to solve these problems.
上記問題を解決するためには、生化学分析にかかわる一
連の作業、つまり遠心分離機２分注装置生化学分析装置
を一連の搬送システムで結合することにより達成される
。In order to solve the above problems, a series of operations related to biochemical analysis, that is, a centrifugal separator, two dispensing devices, and a biochemical analyzer are connected by a series of transport systems.
すなわち、遠心分離機は複数個の検体を挿入しうる検体
用ラックを自動的に搬送する搬送装置を備え、更に好ま
しくはアンバランス補正用のスペアラックを配置し得る
遠心分離装置と分注装置間を搬送ラインで結合する。分
注装置では、検体容器の太さ、長さなど異なる試験管か
ら分析装置専用の試料容器に自動的に血清を分注し、生
化学自動分析装置との間に設けた搬送ライン上を走行す
る試料容器用ラックにより上記試料容器を自動的に搬送
するように構成する。That is, the centrifugal separator is equipped with a transport device that automatically transports a sample rack into which a plurality of specimens can be inserted, and more preferably between the centrifugal separator and the dispensing device in which a spare rack for unbalance correction can be arranged. are connected by a conveyor line. The dispensing device automatically dispenses serum from test tubes of different sample container thicknesses and lengths into sample containers dedicated to the analyzer, and runs on a transport line installed between it and the automatic biochemistry analyzer. The sample container rack is configured to automatically transport the sample container.
ラック投入口にセットされた検体容器用ラックは、搬送
ラインを通じてラック吊下げ搬送装置の下に送られ、こ
の装置によって順次遠心分離機に搬送される。遠心分離
機はとり込んだラックの数を管理し、遠心分離機の中が
全て検体容器ラックで満たされるまで搬送が続けられる
。もし遠心分離機の内部を全て満たすだけの検体検出用
ラックが送られてこない場合は、その数に応じて中心に
対して対称の数になるようスペア−ラックが挿入される
。スペア−ラックは、検体収容ラックの数がいくらであ
っても、１個有ればその目的が達せられる。The sample container racks set in the rack input ports are sent through a transport line to below a rack suspension transport device, and sequentially transported to a centrifuge by this device. The centrifuge manages the number of racks taken in, and transport continues until the centrifuge is completely filled with sample container racks. If enough specimen detection racks are not sent to fill the entire interior of the centrifuge, then spare racks are inserted so that they are symmetrical in number with respect to the center. No matter how many sample storage racks there are, the purpose of one spare rack can be achieved.
分注部は自動分析装置専用のサンプルカップに試料を移
し変えることにより、検体容器用ラック内の検体容器の
長さ、太さが異なる場合でもその分析を可能としている
。By transferring the sample to a sample cup dedicated to the automatic analyzer, the dispensing section enables analysis of sample containers in the sample container rack, even when the lengths and thicknesses of the sample containers differ.
本発明の一実施例を第１図に、検体容器用ラック図の例
を第２図に、試料容器ラックの例を第３図に示す。An embodiment of the present invention is shown in FIG. 1, an example of a sample container rack is shown in FIG. 2, and an example of a sample container rack is shown in FIG.
第１図において、１は遠心分離装置、２は分注装置、３
は生化学自動分析装置である。第２図のように採血後の
検体（試験管又は真空採血管）４゜４′は、専用の検体
容器用ラック５に挿入されたあと、第１図の検体用トレ
イ６のラック投入ロアにセットされる。この検体用トレ
イ６は、ラックが投入されると検体搬送ライン８にラッ
ク５を自動的に移動させ、更に検体搬送ライン８によっ
てラックはラック停止位置９へ移動させられる。In Figure 1, 1 is a centrifugal separator, 2 is a dispensing device, and 3 is a centrifugal separator.
is an automatic biochemical analyzer. As shown in Fig. 2, the sample (test tube or vacuum blood collection tube) 4゜4' after blood collection is inserted into the dedicated sample container rack 5, and then placed in the rack input lower of the sample tray 6 shown in Fig. 1. Set. This specimen tray 6 automatically moves the rack 5 to the specimen transport line 8 when the rack is loaded, and further moves the rack to a rack stop position 9 by the specimen transport line 8.
遠心弁Ｍ装置１には遠心用ロータ１０があり。The centrifugal valve M device 1 includes a centrifugal rotor 10.
一定の割り出しのちとにロータのロード位置１１にラッ
ク取（＝ｒ位置１２，１３．１４が回転停止する機能を
持つ。ラック停止位ｔｉ！９にある検体容器用ラックは
ラック吊下げ搬送装置１５によってロータロード位置１
１に搬送される。検体用トレイ６に検体用ラックが複数
個存在する場合は、連続して遠心用ロータ１０のロード
位置を１２．１３゜１４と移動させて検体用ラックを遠
心用ロータ１０内のすべてのロード位置に挿入すること
ができる。もしこの検体用ラックが単数もしくは奇数な
どの場合、ラック停止位置９からの検体ラックの数をカ
ウントして、一定時間経過しても次のラックが来ない場
合や、外部より指令を与えた場合、遠心用ロータ内のバ
ランスを取るために別に用意したスペア−ラック１６を
空白部分に装着する。After a certain indexing, the rack is placed at the loading position 11 of the rotor (= r positions 12, 13, and 14 have the function of stopping rotation. The rack for the sample container at the rack stop position ti!9 is moved to the rack hanging conveyance device 15. By rotor load position 1
1. If there are multiple specimen racks in the specimen tray 6, the loading position of the centrifugation rotor 10 is successively moved to 12.13°14, so that the specimen racks are placed in all the loading positions in the centrifugation rotor 10. can be inserted into. If there is a single or odd number of sample racks, count the number of sample racks from the rack stop position 9, and if the next rack does not come after a certain period of time, or if a command is given from outside. In order to balance the inside of the centrifugal rotor, a separately prepared spare rack 16 is installed in the blank space.
例えば検体用ラックが１個しかない場合、ロータロード
位置１１には検体用ラック５を、又１８０゜回転した位
置にはスペア−ラック１６を挿入すればよい。For example, if there is only one sample rack, the sample rack 5 may be inserted into the rotor load position 11, and the spare rack 16 may be inserted into a position rotated by 180 degrees.
このようにして遠心分離が完了したとき、スペア−ラッ
ク１６は元の位置に戻され、検体用ラック５は搬送ライ
ン１７に乗せかえて、自動的に次工程の分注装置２へ移
動する。When the centrifugation is completed in this way, the spare rack 16 is returned to its original position, and the sample rack 5 is placed on the transport line 17 and automatically moved to the next step, the dispensing device 2.
一方、分注装置２では生化学自動分析装置３専用の試料
容器へ血清を分注する必要がある。このために分注装置
２の手前に空の試料容器１８の乗った試料容器用ラック
１９を配置しておき、自動的に分注装置２の分注位置２
０に移動待機させる。On the other hand, in the dispensing device 2, it is necessary to dispense serum into a sample container dedicated to the automatic biochemical analyzer 3. For this purpose, a sample container rack 19 on which empty sample containers 18 are placed is arranged in front of the dispensing device 2, and the dispensing position 2 of the dispensing device 2 is automatically
Move to 0 and wait.
分注装置２では検体容器に付加された検体識別記号２１
を読み取り必要な分量の血清を試料容器１８八分注する
。試料容器１８は検体容器４の読み取り順に配列され、
生化学自動分析装置３へ送り出されるので、順番が異な
ることなく処理が行なえる。分注したあとの検体用ラッ
ク５は、搬送ライン１７により検体収容部２２へ送られ
、又生化学自動分析装置３で分析したあとの残量を有す
る試料容器１８は試料容器収容部２３へ送られる。In the dispensing device 2, the sample identification symbol 21 added to the sample container
Pour the required amount of serum into 18 sample containers. The sample containers 18 are arranged in the reading order of the sample containers 4,
Since the data are sent to the biochemical automatic analyzer 3, processing can be performed without changing the order. The sample rack 5 after being dispensed is sent to the sample storage section 22 via the transport line 17, and the sample container 18 containing the remaining amount after being analyzed by the biochemical automatic analyzer 3 is sent to the sample container storage section 23. It will be done.
検体容器４，４′などはその太さ、長さなどの異なるも
のが混在しても分注装＠２で専用の試料容器１８へ移す
ので処理に支障は及ぼさない。又検体容器ラックは全て
が検体容器で満たされるとは限らない。このような場合
でも遠心用ロータ１０のアンバランス重量以内の容器収
容数にすることにより、例えば検体容器が１本しかなく
ても遠心分離及び分析の可能なシステムを堤供すること
ができる。Even if sample containers 4, 4', etc. with different thicknesses and lengths coexist, they are transferred to a dedicated sample container 18 using the dispensing device @2, so that there is no problem with the processing. Furthermore, the sample container racks are not necessarily all filled with sample containers. Even in such a case, by keeping the number of containers accommodated within the unbalanced weight of the centrifugal rotor 10, it is possible to provide a system capable of centrifugation and analysis even if there is only one sample container, for example.
このように本システムを構成することにより、（１）検
体を遠心機に投入してから分析処理、検体及び試料の収
容まで人手の触れることがないため感染のおそれがない
、（２）分析装置への検体のとり違えかない、（３）検
体容器の種別を問わない、（４）すべてオンライン結合
のため結果の迅速報告が可能などの効果がある。By configuring this system in this way, (1) there is no risk of infection since there is no human contact from the time the sample is put into the centrifuge to the analysis processing and the storage of the sample and sample; (2) there is no risk of infection; (3) It does not matter the type of sample container, and (4) it allows rapid reporting of results because everything is combined online.
第１図は本発明の一実施例の生化学自動分析システムの
構成例を示す図、第２図は検体容器及びそのラック形状
の例を示す図、第３図は試料容器及びそのラック形状の
例を示す図である。
１・・・遠心分離装置、２・・・分注装置、３・・・生
化学自動分析装置、５・・・検体容器用ラック、８・・
・検体搬送ライン、９・・・ラック停止位置、１０・・
・遠心用ロータ、１１・・・ロータロード位置、１６・
・・スペア−ラック、１７・・・搬送ライン、１９・・
・試料容器用ラック、２０・・分注位置。
率１図FIG. 1 is a diagram showing an example of the configuration of an automatic biochemical analysis system according to an embodiment of the present invention, FIG. 2 is a diagram showing an example of the shape of a sample container and its rack, and FIG. 3 is a diagram showing an example of the shape of a sample container and its rack. It is a figure which shows an example. 1... Centrifugal separator, 2... Dispensing device, 3... Biochemical automatic analyzer, 5... Rack for specimen containers, 8...
・Sample transport line, 9... Rack stop position, 10...
・Centrifugal rotor, 11...Rotor load position, 16・
... Spare rack, 17... Conveyance line, 19...
・Rack for sample containers, 20...Dispensing position. rate 1 diagram
Claims (1)
容器用ラックと、この検体容器用ラックを遠心分離用ロ
ータに自動的に積み下しするラック搬送装置を備えた遠
心分離装置と、この遠心分離装置で分離した検体容器内
の上清層を別容器である試料容器に移すための分注装置
と、この試料容器の検体成分を化学分析する生化学自動
分析装置と、上記遠心分離装置と上記分注装置との間で
上記検体容器用ラックを搬送する搬送ラインと、上記試
料容器を挿入しうる試料容器用ラックと、この試料容器
用ラックを上記分注装置と上記生化学自動分析装置との
間で搬送する搬送ラインとを備えたことを特徴とする生
化学自動分析システム。 ２、特許請求の範囲第１項において、前記遠心分離装置
は、遠心分離時のアンバランス補正用スペアラックを備
え、前記検体容器用ラックを乗せたときの前記遠心分離
用ロータのアンバランスを上記スペアラックで補正する
機構を備えたことを特徴とする生化学自動分析システム
。[Claims] 1. A rack for specimen containers into which a plurality of specimen containers containing specimens can be inserted, and a rack transport device for automatically loading and unloading the rack for specimen containers onto a rotor for centrifugation. a centrifugal separator, a dispensing device for transferring the supernatant layer in the sample container separated by the centrifuge to a separate sample container, and an automatic biochemical analysis device for chemically analyzing the sample components in the sample container. a transport line that transports the sample container rack between the centrifugal separator and the dispensing device, a sample container rack into which the sample container can be inserted, and a sample container rack that transports the sample container rack into the dispensing device. An automatic biochemical analysis system comprising a transport line for transporting between the device and the automatic biochemical analyzer. 2. In Claim 1, the centrifugal separator is provided with a spare rack for correcting unbalance during centrifugation, and the centrifugal separation apparatus corrects the unbalance of the centrifugal rotor when the sample container rack is placed on it. A biochemical automatic analysis system characterized by being equipped with a correction mechanism using a spare rack.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63214987A JP2656567B2 (en) | 1988-08-31 | 1988-08-31 | Automatic analysis system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP63214987A JP2656567B2 (en) | 1988-08-31 | 1988-08-31 | Automatic analysis system |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH0264462A true JPH0264462A (en) | 1990-03-05 |
| JP2656567B2 JP2656567B2 (en) | 1997-09-24 |
Family
ID=16664827
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63214987A Expired - Lifetime JP2656567B2 (en) | 1988-08-31 | 1988-08-31 | Automatic analysis system |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP2656567B2 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07167866A (en) * | 1994-09-19 | 1995-07-04 | Hitachi Ltd | Specimen conveyor for clinical examination |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3410018B2 (en) * | 1998-04-20 | 2003-05-26 | 株式会社日立製作所 | Sample dispensing device and sample processing system |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5029571U (en) * | 1973-07-13 | 1975-04-03 | ||
| JPS50139787A (en) * | 1974-04-26 | 1975-11-08 | ||
| JPS5318908A (en) * | 1976-08-06 | 1978-02-21 | Hitachi Ltd | Jitter measurement instrument |
| JPS54117974A (en) * | 1978-03-03 | 1979-09-13 | Hitachi Koki Co Ltd | Device for charging racks into centrifugal separator |
| JPS5637506A (en) * | 1979-09-05 | 1981-04-11 | Janome Sewing Mach Co Ltd | Current position recognizing device of automobile |
| JPS57111451A (en) * | 1980-12-29 | 1982-07-10 | Olympus Optical Co Ltd | Dispensing method for particle sample |
| JPS57111447A (en) * | 1980-12-29 | 1982-07-10 | Olympus Optical Co Ltd | Analyzer based on immunological agglutination reaction |
| JPS57111452A (en) * | 1980-12-29 | 1982-07-10 | Olympus Optical Co Ltd | Dispensing method for sample and reagent |
| JPS5827985A (en) * | 1981-08-12 | 1983-02-18 | Nippon Paint Co Ltd | Controlling method for dip coating type phosphating |
-
1988
- 1988-08-31 JP JP63214987A patent/JP2656567B2/en not_active Expired - Lifetime
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5029571U (en) * | 1973-07-13 | 1975-04-03 | ||
| JPS50139787A (en) * | 1974-04-26 | 1975-11-08 | ||
| JPS5318908A (en) * | 1976-08-06 | 1978-02-21 | Hitachi Ltd | Jitter measurement instrument |
| JPS54117974A (en) * | 1978-03-03 | 1979-09-13 | Hitachi Koki Co Ltd | Device for charging racks into centrifugal separator |
| JPS5637506A (en) * | 1979-09-05 | 1981-04-11 | Janome Sewing Mach Co Ltd | Current position recognizing device of automobile |
| JPS57111451A (en) * | 1980-12-29 | 1982-07-10 | Olympus Optical Co Ltd | Dispensing method for particle sample |
| JPS57111447A (en) * | 1980-12-29 | 1982-07-10 | Olympus Optical Co Ltd | Analyzer based on immunological agglutination reaction |
| JPS57111452A (en) * | 1980-12-29 | 1982-07-10 | Olympus Optical Co Ltd | Dispensing method for sample and reagent |
| JPS5827985A (en) * | 1981-08-12 | 1983-02-18 | Nippon Paint Co Ltd | Controlling method for dip coating type phosphating |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07167866A (en) * | 1994-09-19 | 1995-07-04 | Hitachi Ltd | Specimen conveyor for clinical examination |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2656567B2 (en) | 1997-09-24 |
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