JPH0260267B2 - - Google Patents
Info
- Publication number
- JPH0260267B2 JPH0260267B2 JP25497884A JP25497884A JPH0260267B2 JP H0260267 B2 JPH0260267 B2 JP H0260267B2 JP 25497884 A JP25497884 A JP 25497884A JP 25497884 A JP25497884 A JP 25497884A JP H0260267 B2 JPH0260267 B2 JP H0260267B2
- Authority
- JP
- Japan
- Prior art keywords
- human protein
- protein
- human
- calcium ions
- activity
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940100689 human protein c Drugs 0.000 claims description 82
- 101500025568 Homo sapiens Saposin-D Proteins 0.000 claims description 81
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims description 45
- 229910001424 calcium ion Inorganic materials 0.000 claims description 45
- 230000000694 effects Effects 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 24
- 239000011575 calcium Substances 0.000 claims description 23
- 239000003463 adsorbent Substances 0.000 claims description 18
- 239000000758 substrate Substances 0.000 claims description 9
- 108090000190 Thrombin Proteins 0.000 claims description 7
- 229960004072 thrombin Drugs 0.000 claims description 7
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- 101800004937 Protein C Proteins 0.000 description 21
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- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 18
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- 101000595198 Homo sapiens Podocalyxin Proteins 0.000 description 16
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- PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical compound NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 description 6
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- UHBYWPGGCSDKFX-VKHMYHEASA-N gamma-carboxy-L-glutamic acid Chemical compound OC(=O)[C@@H](N)CC(C(O)=O)C(O)=O UHBYWPGGCSDKFX-VKHMYHEASA-N 0.000 description 6
- 238000002649 immunization Methods 0.000 description 6
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- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 5
- 239000000872 buffer Substances 0.000 description 5
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- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
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- SHUZOJHMOBOZST-UHFFFAOYSA-N phylloquinone Natural products CC(C)CCCCC(C)CCC(C)CCCC(=CCC1=C(C)C(=O)c2ccccc2C1=O)C SHUZOJHMOBOZST-UHFFFAOYSA-N 0.000 description 1
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- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25497884A JPS61133861A (ja) | 1984-12-04 | 1984-12-04 | ヒト・プロテインｃ活性の測定方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP25497884A JPS61133861A (ja) | 1984-12-04 | 1984-12-04 | ヒト・プロテインｃ活性の測定方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS61133861A JPS61133861A (ja) | 1986-06-21 |
| JPH0260267B2 true JPH0260267B2 (ru) | 1990-12-14 |
Family
ID=17272509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP25497884A Granted JPS61133861A (ja) | 1984-12-04 | 1984-12-04 | ヒト・プロテインｃ活性の測定方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS61133861A (ru) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0285511B1 (en) * | 1987-04-01 | 1992-11-25 | Mitsubishi Gas Chemical Company, Inc. | Immunoassay of thrombomodulin |
-
1984
- 1984-12-04 JP JP25497884A patent/JPS61133861A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61133861A (ja) | 1986-06-21 |
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