JPH0260256B2 - - Google Patents

Info

Publication number
JPH0260256B2
JPH0260256B2 JP60061751A JP6175185A JPH0260256B2 JP H0260256 B2 JPH0260256 B2 JP H0260256B2 JP 60061751 A JP60061751 A JP 60061751A JP 6175185 A JP6175185 A JP 6175185A JP H0260256 B2 JPH0260256 B2 JP H0260256B2
Authority
JP
Japan
Prior art keywords
light
prism
cells
particles
end surface
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60061751A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60224040A (ja
Inventor
Etsuchi Seiji Juniaa Baaton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of JPS60224040A publication Critical patent/JPS60224040A/ja
Publication of JPH0260256B2 publication Critical patent/JPH0260256B2/ja
Granted legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1468—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle
    • G01N15/147—Optical investigation techniques, e.g. flow cytometry with spatial resolution of the texture or inner structure of the particle the analysis being performed on a sample stream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N2015/1497—Particle shape
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2201/00—Features of devices classified in G01N21/00
    • G01N2201/06—Illumination; Optics
    • G01N2201/063—Illuminating optical parts
    • G01N2201/0631—Homogeneising elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP60061751A 1984-03-26 1985-03-26 流動細胞計数装置 Granted JPS60224040A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/593,470 US4600302A (en) 1984-03-26 1984-03-26 Flow cytometry apparatus with uniform incoherent light excitation
US593470 1984-03-26

Publications (2)

Publication Number Publication Date
JPS60224040A JPS60224040A (ja) 1985-11-08
JPH0260256B2 true JPH0260256B2 (enrdf_load_html_response) 1990-12-14

Family

ID=24374843

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60061751A Granted JPS60224040A (ja) 1984-03-26 1985-03-26 流動細胞計数装置

Country Status (3)

Country Link
US (1) US4600302A (enrdf_load_html_response)
EP (1) EP0158147A2 (enrdf_load_html_response)
JP (1) JPS60224040A (enrdf_load_html_response)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4660971A (en) * 1984-05-03 1987-04-28 Becton, Dickinson And Company Optical features of flow cytometry apparatus
US4643566A (en) * 1984-07-20 1987-02-17 Canon Kabushiki Kaisha Particle analyzing apparatus
US4701664A (en) * 1986-01-09 1987-10-20 Becton, Dickinson And Company Mercury arc lamp suitable for inclusion in a flow cytometry apparatus
JPS63151855A (ja) * 1986-12-16 1988-06-24 Japan Spectroscopic Co フロ−セル兼用ノズル
JP2529966B2 (ja) * 1987-03-28 1996-09-04 株式会社東芝 粒径測定装置
JP3075367B2 (ja) * 1991-04-05 2000-08-14 シスメックス株式会社 粒子分析方法及び装置
JPH0526810A (ja) * 1991-07-23 1993-02-02 Hamamatsu Photonics Kk 微粒子の螢光検出装置
US5692066A (en) * 1994-09-20 1997-11-25 Neopath, Inc. Method and apparatus for image plane modulation pattern recognition
DE782701T1 (de) * 1994-09-20 1998-11-12 Neopath Inc Vorrichtung zur illuminierung, stabilisierung und homogenisierung
JPH09138712A (ja) * 1995-08-29 1997-05-27 Nec Corp 相互接続ネットワーク
EP1562035B1 (en) 1997-01-31 2017-01-25 Xy, Llc Optical apparatus and method
US6071689A (en) 1997-12-31 2000-06-06 Xy, Inc. System for improving yield of sexed embryos in mammals
US6149867A (en) 1997-12-31 2000-11-21 Xy, Inc. Sheath fluids and collection systems for sex-specific cytometer sorting of sperm
US6248590B1 (en) 1998-02-27 2001-06-19 Cytomation, Inc. Method and apparatus for flow cytometry
DK1100534T3 (da) 1998-07-30 2008-03-10 Xy Inc System til ikke-kirurgisk kunstig insemination af heste
US7024316B1 (en) 1999-10-21 2006-04-04 Dakocytomation Colorado, Inc. Transiently dynamic flow cytometer analysis system
US7208265B1 (en) 1999-11-24 2007-04-24 Xy, Inc. Method of cryopreserving selected sperm cells
ATE418071T1 (de) * 2000-03-15 2009-01-15 Inverness Medical Switzerland Verfahren zur herstellung mindestens eines hüllflusses in einem kanal
NZ551401A (en) 2000-05-09 2009-12-24 Xy Inc A particle differentiation apparatus which differentiates between X-chromosome bearing and Y-chromosome bearing populations of spermatozoa
US7713687B2 (en) 2000-11-29 2010-05-11 Xy, Inc. System to separate frozen-thawed spermatozoa into x-chromosome bearing and y-chromosome bearing populations
AU2002237689B2 (en) 2000-11-29 2008-01-10 Xy, Llc. System to separate frozen-thawed spermatozoa into X-chromosome bearing and Y-chromosome bearing populations
WO2002092247A1 (en) 2001-05-17 2002-11-21 Cytomation, Inc. Flow cytometer with active automated optical alignment system
US20030211009A1 (en) * 2001-05-18 2003-11-13 Buchanan Kris S. Rapid multi-material sample input system
US6932796B2 (en) * 2002-05-15 2005-08-23 Tearafuse, Inc. Liquid metering system
US8486618B2 (en) 2002-08-01 2013-07-16 Xy, Llc Heterogeneous inseminate system
MX337304B (es) 2002-08-01 2016-02-24 Xy Llc Sistema de separacion de baja presion para celulas de esperma.
CA2534394C (en) 2002-08-15 2013-01-08 Xy, Inc. High resolution flow cytometer
US7169548B2 (en) 2002-09-13 2007-01-30 Xy, Inc. Sperm cell processing and preservation systems
EP3511693B1 (en) 2003-03-28 2022-08-24 Inguran, LLC Apparatus for detecting the breakoff point of a droplet generation system
WO2004102201A1 (en) * 2003-05-07 2004-11-25 Novasite Pharmaceuticals, Inc. Gain of function sorting for drug discovery and development
EP1625385A1 (en) * 2003-05-07 2006-02-15 Novasite Pharmaceuticals, Inc. Multiplexed multitarget screening method
US20060263829A1 (en) 2003-05-15 2006-11-23 Evans Kenneth M Efficient haploid cell sorting flow cytometer systems
JP2007531523A (ja) 2004-03-29 2007-11-08 モンサント テクノロジー エルエルシー Ｘまたはｙ染色体担持豊富化集団に仕分けるための精子懸濁液
AU2005266930B2 (en) 2004-07-22 2010-09-16 Inguran, Llc Process for enriching a population of sperm cells
DK2884258T3 (da) 2004-07-27 2017-01-02 Beckman Coulter Inc Forbedring af flowcytometrisk diskrimination med computerimplementeret geometrisk transformation
DE202005003411U1 (de) * 2005-02-24 2006-07-06 Karl Storz Gmbh & Co. Kg Multifunktionales Fluoreszenzdiagnosesystem
US7618770B2 (en) 2005-07-29 2009-11-17 Xy, Inc. Methods and apparatus for reducing protein content in sperm cell extenders
US8858787B2 (en) 2007-10-22 2014-10-14 Baxter International Inc. Dialysis system having non-invasive fluid velocity sensing
EP2232229B1 (en) 2007-12-04 2021-02-17 Particle Measuring Systems, Inc. Two-dimensional optical imaging methods for particle detection
WO2014176366A1 (en) * 2013-04-26 2014-10-30 Van Den Engh Gerrit J Methods and systems for the collection of light using total internal reflectance
WO2016133760A1 (en) 2015-02-18 2016-08-25 Becton, Dickinson And Company Optical detection systems and methods of using the same
EP3265858B1 (en) 2015-03-06 2022-11-16 Becton, Dickinson and Company Light collection systems and methods for making and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2144588B2 (de) * 1971-09-07 1978-11-02 Gebr. Happich Gmbh, 5600 Wuppertal Strahlenleitkörper für Kontrolloder Bedienungselemente von Fahrzeugen
DE2427182A1 (de) * 1974-06-05 1975-12-18 Richard Gareis Lampenkoerper mit energiezufuhr durch lichtleitung
JPS5326996A (en) * 1976-08-26 1978-03-13 Tokyo Keiki Kk Compound dielectric body
US4348107A (en) * 1980-07-18 1982-09-07 Coulter Electronics, Inc. Orifice inside optical element
US4451149A (en) * 1980-07-28 1984-05-29 Noeller Hans Guenter Polarization fluoroimmunoassay apparatus
US4498766A (en) * 1982-03-25 1985-02-12 Becton, Dickinson And Company Light beam focal spot elongation in flow cytometry devices

Also Published As

Publication number Publication date
JPS60224040A (ja) 1985-11-08
EP0158147A2 (en) 1985-10-16
US4600302A (en) 1986-07-15

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