JPH0224831B2 - - Google Patents

Info

Publication number
JPH0224831B2
JPH0224831B2 JP55131786A JP13178680A JPH0224831B2 JP H0224831 B2 JPH0224831 B2 JP H0224831B2 JP 55131786 A JP55131786 A JP 55131786A JP 13178680 A JP13178680 A JP 13178680A JP H0224831 B2 JPH0224831 B2 JP H0224831B2
Authority
JP
Japan
Prior art keywords
formula
compounds
triazolo
pyridin
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP55131786A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5697285A (en
Inventor
Efu Moroo Daan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPS5697285A publication Critical patent/JPS5697285A/ja
Publication of JPH0224831B2 publication Critical patent/JPH0224831B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/06—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals
    • C07D295/067—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by halogen atoms or nitro radicals with the ring nitrogen atoms and the substituents attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP13178680A 1979-09-24 1980-09-24 Antidepressive Granted JPS5697285A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/078,536 US4254124A (en) 1979-09-24 1979-09-24 Antidepressant agent

Publications (2)

Publication Number Publication Date
JPS5697285A JPS5697285A (en) 1981-08-05
JPH0224831B2 true JPH0224831B2 (en, 2012) 1990-05-30

Family

ID=22144661

Family Applications (1)

Application Number Title Priority Date Filing Date
JP13178680A Granted JPS5697285A (en) 1979-09-24 1980-09-24 Antidepressive

Country Status (7)

Country Link
US (1) US4254124A (en, 2012)
EP (1) EP0025985B1 (en, 2012)
JP (1) JPS5697285A (en, 2012)
AT (1) ATE5407T1 (en, 2012)
CA (1) CA1153376A (en, 2012)
DE (1) DE3065697D1 (en, 2012)
GR (1) GR82325B (en, 2012)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4465683A (en) * 1979-09-14 1984-08-14 Mead Johnson & Company Anti-psychotic agents
KR100343948B1 (ko) * 1999-11-16 2002-07-24 한국과학기술연구원 피페라지닐에틸 트리아졸 화합물 및 그 제조방법
ITMI20071603A1 (it) * 2007-08-03 2009-02-04 Acraf Trazodone e trazodone cloridrato in forma purificata
HK1215170A1 (zh) 2012-11-14 2016-08-19 The Johns Hopkins University 治療精神分裂症的方法和組合物
BR112020015885A2 (pt) 2018-02-07 2020-12-08 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A Processo contínuo para preparação de trazodona.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1066857B (it) * 1965-12-15 1985-03-12 Acraf Derivati della s ipiazolo 4.3 a piridina e processi per la loro preparazione
FR8135M (en, 2012) * 1968-12-31 1970-08-10
IT1052119B (it) * 1972-10-16 1981-06-20 Sigma Tau Ind Farmaceuti Derivati del triazolinone e procedimento per la loro preparazione
IT1041817B (it) * 1975-08-12 1980-01-10 Acraf Prodotto farmaceutico utilizzabile nelle sindrommi cerebrali

Also Published As

Publication number Publication date
US4254124A (en) 1981-03-03
EP0025985B1 (en) 1983-11-23
ATE5407T1 (de) 1983-12-15
JPS5697285A (en) 1981-08-05
GR82325B (en, 2012) 1984-12-13
EP0025985A1 (en) 1981-04-01
DE3065697D1 (en) 1983-12-29
CA1153376A (en) 1983-09-06

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