JPH0153253B2 - - Google Patents
Info
- Publication number
- JPH0153253B2 JPH0153253B2 JP55054279A JP5427980A JPH0153253B2 JP H0153253 B2 JPH0153253 B2 JP H0153253B2 JP 55054279 A JP55054279 A JP 55054279A JP 5427980 A JP5427980 A JP 5427980A JP H0153253 B2 JPH0153253 B2 JP H0153253B2
- Authority
- JP
- Japan
- Prior art keywords
- silicic anhydride
- tablets
- herbal medicine
- concentrate
- added
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 56
- 241000411851 herbal medicine Species 0.000 claims description 36
- 239000002245 particle Substances 0.000 claims description 29
- 239000011148 porous material Substances 0.000 claims description 29
- 239000000284 extract Substances 0.000 claims description 20
- 239000012141 concentrate Substances 0.000 claims description 19
- 238000001694 spray drying Methods 0.000 claims description 10
- 238000000748 compression moulding Methods 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 4
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims description 4
- 235000012239 silicon dioxide Nutrition 0.000 claims description 4
- 239000000314 lubricant Substances 0.000 claims description 2
- 239000003826 tablet Substances 0.000 description 52
- 239000000843 powder Substances 0.000 description 14
- 239000010358 hachimijiogan Substances 0.000 description 13
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 9
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 8
- 239000004615 ingredient Substances 0.000 description 7
- 229910002012 Aerosil® Inorganic materials 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000007788 liquid Substances 0.000 description 6
- 229910002016 Aerosil® 200 Inorganic materials 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 241000736199 Paeonia Species 0.000 description 4
- 235000019359 magnesium stearate Nutrition 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000008704 toki-shakuyaku-san Substances 0.000 description 4
- 235000006484 Paeonia officinalis Nutrition 0.000 description 3
- 241000375392 Tana Species 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000011521 glass Substances 0.000 description 3
- 238000009777 vacuum freeze-drying Methods 0.000 description 3
- 229920000168 Microcrystalline cellulose Polymers 0.000 description 2
- 244000131316 Panax pseudoginseng Species 0.000 description 2
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 description 2
- 235000003140 Panax quinquefolius Nutrition 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 235000010980 cellulose Nutrition 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 235000008434 ginseng Nutrition 0.000 description 2
- 235000019813 microcrystalline cellulose Nutrition 0.000 description 2
- 239000008108 microcrystalline cellulose Substances 0.000 description 2
- 229940016286 microcrystalline cellulose Drugs 0.000 description 2
- 239000007921 spray Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- 235000001674 Agaricus brunnescens Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 241000218671 Ephedra Species 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 240000004670 Glycyrrhiza echinata Species 0.000 description 1
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 description 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 description 1
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 244000046146 Pueraria lobata Species 0.000 description 1
- 235000010575 Pueraria lobata Nutrition 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 244000273928 Zingiber officinale Species 0.000 description 1
- 235000006886 Zingiber officinale Nutrition 0.000 description 1
- 244000126002 Ziziphus vulgaris Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000007891 compressed tablet Substances 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 238000002845 discoloration Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 230000008014 freezing Effects 0.000 description 1
- 235000008397 ginger Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229940010454 licorice Drugs 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 229920001592 potato starch Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 239000011163 secondary particle Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 239000011882 ultra-fine particle Substances 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
- 238000005550 wet granulation Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5427980A JPS56152416A (en) | 1980-04-25 | 1980-04-25 | Preparation of chinese herbal remedy tablet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5427980A JPS56152416A (en) | 1980-04-25 | 1980-04-25 | Preparation of chinese herbal remedy tablet |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56152416A JPS56152416A (en) | 1981-11-26 |
| JPH0153253B2 true JPH0153253B2 (zh) | 1989-11-13 |
Family
ID=12966120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP5427980A Granted JPS56152416A (en) | 1980-04-25 | 1980-04-25 | Preparation of chinese herbal remedy tablet |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56152416A (zh) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6133122A (ja) * | 1984-07-25 | 1986-02-17 | Daicel Chem Ind Ltd | 崩壊性良好な錠剤の製法 |
| JPH01165527A (ja) * | 1987-12-23 | 1989-06-29 | Tsumura & Co | 漢方薬エキス剤の製造方法 |
| ES2188928T3 (es) * | 1996-04-26 | 2003-07-01 | Shionogi & Co | Pastilla de liberador-rapido s1452. |
| JPWO2002021941A1 (ja) * | 2000-09-12 | 2004-05-27 | 義秀 萩原 | 新規酢海藻粉末又は顆粒及びその製造方法 |
| CA2492156C (en) * | 2002-07-12 | 2012-09-18 | Tsumura & Co. | Tablet composition containing kampo medicinal extract and its manufacturing process |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5555113A (en) * | 1978-10-18 | 1980-04-22 | Beiersdorf Ag | Oral administration medical tablet and its manufacture |
-
1980
- 1980-04-25 JP JP5427980A patent/JPS56152416A/ja active Granted
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5555113A (en) * | 1978-10-18 | 1980-04-22 | Beiersdorf Ag | Oral administration medical tablet and its manufacture |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS56152416A (en) | 1981-11-26 |
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