JPH01256587A - Antioxidant composition - Google Patents

Abstract

PURPOSE:To prevent the oxidation of an unsaturated oil or fat and a surface active agent to thereby prevent the deterioration of external preparations for skin, such as a cosmetic, and impart stability and safety thereto, by incorporating a vitamin E and a mulberry bark extract therein. CONSTITUTION:For example, based on the total weight of a final product such as a cosmetic cream, 0.0001-5.0wt.% vitamin E comprising, e.g., natural vitamin E, or alpha-, beta-, gamma- or delta-tocopherol and 0.0001-3.0wt.% mulberry bark extract obtained by extraction from the root bark of, e.g., mulberry, Chinese mulberry, Morus bombycis or white mulberry of the mulberry family after removing a cork layer therefrom, are incorporated into said product.

Description

[Detailed Description of the Invention] [Industrial Application Field] The present invention relates to an antioxidant composition, more specifically, it is suitable for external skin products and contains vitamin E and mulberry bark extract for the purpose of improving antioxidant properties. and an antioxidant composition containing the same.

[Prior Art] In general, unsaturated fats and oils and surfactants are known to be easily oxidized by ultraviolet rays or oxygen in the air, resulting in discoloration and odor. Therefore, products containing these ingredients are Usually, antioxidants are added to prevent acid dispersion.

In addition, in recent years, peroxide has become harmful to the skin, and if peroxide is included in external skin products such as cosmetics, the use of peroxide can cause skin irritation and itching, as well as diseases such as melasma and melasma. It has also been reported that it may cause

Therefore, the role of antioxidants in preventing the formation of peroxides due to oxidation in products is important, and at the same time active consideration is being given to formulations, selection of components such as oils and fats and surfactants is also being carried out. has been needed.

Conventionally, such antioxidants include vitamin E, 2
, 4-di-tert-butyl-P-cresol, ter
Typical examples include t-butylhydroxyanisole and gallic acid ester, which have been used.

[Problems to be Solved by the Invention] However, although the conventionally known antioxidants described above are used with the expectation of preventing oxidation, they have little effect in achieving the intended purpose, and they are used in large amounts. Even when used for this purpose, it has not always been satisfactory because it is difficult to obtain a sufficient effect due to restrictions in formulation, or it is unfavorable in terms of skin safety.

Furthermore, the current situation is that not only does the product prevent oxidation, but lipid peroxide is constantly generated on the skin surface from skin surface lipids, and it has been shown that lipid peroxide has a protein denaturing effect and is related to aging. It is desirable to eliminate peroxides as much as possible, regardless of whether they are derived from peroxides or from skin surface lipids, and it is becoming important to further enhance the antioxidant effect and prevent skin damage caused by peroxides. .

[Means for Solving the Problems] In view of the above-mentioned circumstances, the present inventors have conducted extensive studies to further improve the antioxidant properties, and as a result,
It was discovered that by using vitamin E and mulberry bark extract in combination, the production of peroxides can be effectively suppressed and a remarkable antioxidant effect can be obtained, and the present invention was completed based on this knowledge.

That is, the present invention relates to an antioxidant composition containing vitamin E and mulberry bark extract.

The configuration of the present invention will be explained below.

The vitamin E used in the present invention includes natural vitamin E, α-tocopherol, β-tocopherol, γ-tocopherol, δ-tocopherol, etc., and one or more of these can be appropriately selected and used. .

In addition, the mulberry bark extract in the present invention refers to the mulberry bark extract used in the present invention.
eae)'s mulberry, Karakwa 0 jorus alba L
), Yamaguwa (M, bombycis KOID7
．． ), Magwa (M.

It is obtained by extracting from the root bark of plants such as 1atifolia POIRET, from which the cork layer has been removed.

The extraction method is not particularly limited, but for example, as an extraction solvent,
Water, lower alcohols such as methyl alcohol and ethyl alcohol, liquid polyhydric alcohols such as propylene glycol and 1,3-butylene glycol, lower alkyl esters such as ethyl acetate, hydrocarbons such as benzene and hexane, ethyl ether, etc. One type of stiff straw or a combination of two or more types can be used. An extract obtained by extraction with these extraction solvents at room temperature or with heating and filtration, or a concentrated product thereof is used.

In the present invention, the amount of vitamin E and mulberry bark extract used as an antioxidant composition is 0.0001 to 5.0% by weight in the case of vitamin E, and 0.0001 to 5.0% by weight in the case of mulberry bark extract, based on the total amount of the final product. 0.0001-3.0% by weight as solid content
This range is a preferable and sufficient amount as an effective addition amount to expect an antioxidant effect. These are used by setting and blending the optimum composition ratio according to the purpose.

The antioxidant composition of the present invention contains unsaturated fats and oils that are easily oxidized such as olive oil, jojoba oil, almond oil, squalene, glyceryl monooleate, sorbitan sesquioleate, polyoxyethylene sorbitan trioleate, etc. By using unsaturated surfactants or products containing these, stability in terms of antioxidant properties can be achieved.

The antioxidant composition of the present invention is suitable for use in external skin products such as cosmetics.

Examples of cosmetics include lotions, milky lotions, creams,
Including paste skin cosmetics, facial cleansers, packs,
Makeup cosmetics, hair and scalp products, lip products,
It is suitable for use in nail products and the like, and is extremely useful as it can impart antioxidant stability to these products.

[Example] Next, the present invention will be further explained by giving examples. These do not limit the invention in any way.

Example [+1] Samples shown in Table 1 to confirm the effects of the present invention, ■~■
A stability test against autooxidation was conducted using 5 types.

The test method was based on the AOM test of the Standard Oil and Fat Analysis Test Method (Japan Oil Chemists Association), the oil bath temperature was set at 97.8°C, the air flow rate was set at 2.3 ml/sec, and each This was done by measuring the POV of the sample. The results are in Table 1
Shown below. Note that the data in the table is expressed as the average value of the measurement results obtained by conducting the test three times.

Table 1 As seen in the results in Table 1, when dl-α-tocopherol and mulberry bark extract were used together (samples ■ to ■),
Compared to when each was used alone (samples ■ to ■),
It has been revealed that the pov is low, that the production of peroxides is effectively suppressed relative to methyl oleate, and that the antioxidant effect is significantly exhibited, indicating that it is extremely useful as an antioxidant.

Example [21] POv was measured in the same manner as in Example [11] using the four samples shown in Table 2, ■ to ■. The results are shown in Table 2. still,
The data in the table is expressed as the average value of the measurement results obtained by conducting the test twice.

Table 2 As seen in the results in Table 2, when natural vitamin E and mulberry bark extract were used together (Sample ■), the POV was significantly higher than when each was used alone (Samples ■ to ■). It was revealed that the antioxidant effect was low and significant.

Example [3] Cream (prescription) (% by weight) (11 Olive oil 5.0 (2) Almond oil 10.0 (3) Stearyl alcohol 3.0 (4) Glyceryl monooleate 1.5 (5) Sesquiolein Acid sorbitan 0.5 (6) Monooleate polyoxye 1.0 tyrene sorbitan (20E, O,
) (7) Glycerin 7.0 (8)
α-tocopherol 0.1 (9) Mulberry bark, kiss (ethyl alcohol 5.0 col extraction) 00) Hyaluronic acid 0.0
1 (10 fragrance 0.20
2) Methyl roseoxybenzoate 0.103) Purified water Remaining amount (manufacturing method) Mix components (1) to (4) and heat and dissolve. Gradually add this to components (6) to 03 that were mixed separately and heated and dissolved. The mixture was added to emulsify and cooled to obtain cream.

Example [4] Powder foundation (formulation)
(Weight%) (1) Titanium oxide 1010 (2) Kaolin 25.0 (3) Talc 40.0 (4) Red iron oxide 0.8 (5) Yellow iron oxide 2.5 (6) Black iron oxide
0.1(7) Mica
Remaining amount (8) Olive oil
7.0(9) Sorbitan sesquioleate 1.000) Glycerin 3
．． 0 (b) Natural vitamin E O,0
502) 2-Hydroxy-4-methoxy o,i benzophenone 03) S-Ryki Roll 507 1.0 (
14) Mulberry bark extract (l, 3-buty 0. rungericol extract) 05) Fragrance 0.1 (
+6) Methyl paraoxybenzoate 0.05
(Manufacturing method) Components (1) to (7) are mixed and pulverized to make it homogeneous.

Components (8) to (+6) previously mixed and heated and dissolved were added thereto, mixed uniformly, pulverized, and then press-molded to obtain a powder foundation John.

Example [5] Beer-off type pack (formulation) (wt%) (1)
Vinyl acetate resin emulsion 15.0 (ri) Polyvinyl alcohol 1000 (3) Olive oil 3.0 (4) Natural vitamin E O,1 (uniform) Sorbitan sesquioleate 0.5 ((f) Mulberry bark extract (water extraction) 1 .0(7) Sodium deoxyliponucleic acid
0.01(8) Titanium oxide
8.0(9) Kaolin 7
．． 000) Ethyl alcohol 5.
0(II) Fragrance o,
102) Purified water Remaining amount (manufacturing method) After mixing the components (odor ~ (5), 00), add the component (+2) and dissolve by heating. Next, components (6) to (9) are added to this,
After adding and mixing (b) and cooling, component C1) was added and mixed to obtain a beer-off type pack.

[Effects of the Invention] As detailed above, the present invention provides an antioxidant composition that contains vitamin E and mulberry bark extract and exhibits the antioxidant effects of these components. .

In other words, the present invention has a more remarkable antioxidant effect than ever before, and can prevent the oxidation of unsaturated oils and surfactants, prevent deterioration of products such as cosmetics, and prevent peroxidation. Because it can effectively suppress the formation of peroxides, it can be expected to prevent the harmful effects of peroxide on the skin when added to cosmetics, etc., and further improve stability and safety when used in products. Well, a very useful antioxidant composition has been obtained.

that's all Applicant: Kobayashi Kose Co., Ltd.

Claims (1)

[Claims] (1) An antioxidant composition containing vitamin E and mulberry bark extract.