JPH0122247B2 - - Google Patents
Info
- Publication number
- JPH0122247B2 JPH0122247B2 JP20990081A JP20990081A JPH0122247B2 JP H0122247 B2 JPH0122247 B2 JP H0122247B2 JP 20990081 A JP20990081 A JP 20990081A JP 20990081 A JP20990081 A JP 20990081A JP H0122247 B2 JPH0122247 B2 JP H0122247B2
- Authority
- JP
- Japan
- Prior art keywords
- cephalosporin
- glucose
- present
- molar ratio
- injection
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930186147 Cephalosporin Natural products 0.000 claims description 16
- 229940124587 cephalosporin Drugs 0.000 claims description 16
- 150000001780 cephalosporins Chemical class 0.000 claims description 16
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 13
- 239000008103 glucose Substances 0.000 claims description 13
- 238000002347 injection Methods 0.000 claims description 11
- 239000007924 injection Substances 0.000 claims description 11
- QXNVGIXVLWOKEQ-UHFFFAOYSA-N Disodium Chemical class [Na][Na] QXNVGIXVLWOKEQ-UHFFFAOYSA-N 0.000 claims 1
- 239000000523 sample Substances 0.000 description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 7
- 239000000843 powder Substances 0.000 description 6
- 239000012528 membrane Substances 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 3
- 239000012153 distilled water Substances 0.000 description 3
- 238000001914 filtration Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- VLTRZXGMWDSKGL-UHFFFAOYSA-N perchloric acid Chemical compound OCl(=O)(=O)=O VLTRZXGMWDSKGL-UHFFFAOYSA-N 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 230000005526 G1 to G0 transition Effects 0.000 description 1
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 239000003708 ampul Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000013068 control sample Substances 0.000 description 1
- 238000004128 high performance liquid chromatography Methods 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000008176 lyophilized powder Substances 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20990081A JPS58113125A (ja) | 1981-12-28 | 1981-12-28 | 安定なセフアロスポリン注射剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP20990081A JPS58113125A (ja) | 1981-12-28 | 1981-12-28 | 安定なセフアロスポリン注射剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58113125A JPS58113125A (ja) | 1983-07-05 |
| JPH0122247B2 true JPH0122247B2 (enrdf_load_stackoverflow) | 1989-04-25 |
Family
ID=16580498
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP20990081A Granted JPS58113125A (ja) | 1981-12-28 | 1981-12-28 | 安定なセフアロスポリン注射剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58113125A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6218204B2 (ja) | 2014-09-04 | 2017-10-25 | 塩野義製薬株式会社 | カテコール基を有するセファロスポリン類を含有する製剤 |
-
1981
- 1981-12-28 JP JP20990081A patent/JPS58113125A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58113125A (ja) | 1983-07-05 |
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