JP7797425B2 - ダプロデュスタットを含んでなる処方物 - Google Patents

ダプロデュスタットを含んでなる処方物

Info

Publication number
JP7797425B2
JP7797425B2 JP2022577794A JP2022577794A JP7797425B2 JP 7797425 B2 JP7797425 B2 JP 7797425B2 JP 2022577794 A JP2022577794 A JP 2022577794A JP 2022577794 A JP2022577794 A JP 2022577794A JP 7797425 B2 JP7797425 B2 JP 7797425B2
Authority
JP
Japan
Prior art keywords
tablet
dose
immediate
release tablet
patient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2022577794A
Other languages
English (en)
Japanese (ja)
Other versions
JP2023532223A (ja
JP2023532223A5 (https=
Inventor
サヤンタン、チャットラジ
スコット、ライアン、クロイ
ジェイムズ、アンダーソン、マクラウド
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Intellectual Property No 2 Ltd
Original Assignee
GlaxoSmithKline Intellectual Property No 2 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Intellectual Property No 2 Ltd filed Critical GlaxoSmithKline Intellectual Property No 2 Ltd
Publication of JP2023532223A publication Critical patent/JP2023532223A/ja
Publication of JP2023532223A5 publication Critical patent/JP2023532223A5/ja
Application granted granted Critical
Publication of JP7797425B2 publication Critical patent/JP7797425B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A61K31/515—Barbituric acids; Derivatives thereof, e.g. sodium pentobarbital
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2022577794A 2020-06-19 2021-06-17 ダプロデュスタットを含んでなる処方物 Active JP7797425B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US202063041403P 2020-06-19 2020-06-19
US63/041,403 2020-06-19
US202063043292P 2020-06-24 2020-06-24
US63/043,292 2020-06-24
PCT/EP2021/066386 WO2021255159A1 (en) 2020-06-19 2021-06-17 Formulation comprising daprodustat

Publications (3)

Publication Number Publication Date
JP2023532223A JP2023532223A (ja) 2023-07-27
JP2023532223A5 JP2023532223A5 (https=) 2024-06-18
JP7797425B2 true JP7797425B2 (ja) 2026-01-13

Family

ID=76730508

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022577794A Active JP7797425B2 (ja) 2020-06-19 2021-06-17 ダプロデュスタットを含んでなる処方物

Country Status (7)

Country Link
US (1) US20230225977A1 (https=)
EP (1) EP4167967A1 (https=)
JP (1) JP7797425B2 (https=)
CN (1) CN115697307A (https=)
BR (1) BR112022024533A2 (https=)
CA (1) CA3180509A1 (https=)
WO (1) WO2021255159A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2024521491A (ja) * 2021-06-18 2024-05-31 グラクソスミスクライン、インテレクチュアル、プロパティー、（ナンバー２）、リミテッド ダプロデュスタットおよびその前駆体の新規な製造方法
WO2024257063A1 (en) * 2023-06-16 2024-12-19 Glenmark Life Sciences Limited Solid dispersion of daprodustat and a process for the preparation thereof
WO2025087207A1 (zh) * 2023-10-24 2025-05-01 杭州安道药业有限公司 含有缺氧诱导因子-脯酰胺羟基化酶抑制剂的长效口服药物及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018510178A (ja) 2015-04-01 2018-04-12 アケビア セラピューティクス インコーポレイテッドＡｋｅｂｉａ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 貧血治療のための組成物及び方法
WO2019052133A1 (zh) 2017-09-15 2019-03-21 苏州科睿思制药有限公司 Gsk1278863的晶型及其制备方法和制药用途
WO2020102302A1 (en) 2018-11-15 2020-05-22 Teva Pharmaceuticals International Gmbh Solid state forms of daprodustat and process for preparation thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JO2934B1 (en) 2006-06-23 2015-09-15 سميث كلاين بيتشام كوربوريشن Prolyl hydroxylase inhibitors
CN101773498B (zh) * 2009-12-30 2012-06-20 青岛黄海制药有限责任公司 一种含有非布司他的口服缓控释制剂的制备方法
SI3881833T1 (sl) * 2015-06-30 2024-03-29 Genentech, Inc., Tablete s takojšnjim sproščanjem, ki vsebujejo zdravilo in postopek za oblikovanje tablet
CA2937365C (en) * 2016-03-29 2018-09-18 F. Hoffmann-La Roche Ag Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same
PH12018000227A1 (en) * 2017-09-05 2019-03-11 Frimline Private Ltd A pharmaceutical composition for improving or preventing progression of chronic kidney disease
TWI843707B (zh) * 2017-09-26 2024-06-01 美商提薩羅有限公司 尼拉帕尼（ｎｉｒａｐａｒｉｂ）調配物
CN112955130A (zh) * 2018-10-30 2021-06-11 佩洛通治疗公司 包含取代茚满的固体分散体和药物组合物及其制备和使用方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018510178A (ja) 2015-04-01 2018-04-12 アケビア セラピューティクス インコーポレイテッドＡｋｅｂｉａ Ｔｈｅｒａｐｅｕｔｉｃｓ Ｉｎｃ． 貧血治療のための組成物及び方法
WO2019052133A1 (zh) 2017-09-15 2019-03-21 苏州科睿思制药有限公司 Gsk1278863的晶型及其制备方法和制药用途
WO2020102302A1 (en) 2018-11-15 2020-05-22 Teva Pharmaceuticals International Gmbh Solid state forms of daprodustat and process for preparation thereof

Also Published As

Publication number Publication date
JP2023532223A (ja) 2023-07-27
CA3180509A1 (en) 2021-12-23
US20230225977A1 (en) 2023-07-20
BR112022024533A2 (pt) 2022-12-27
WO2021255159A1 (en) 2021-12-23
EP4167967A1 (en) 2023-04-26
CN115697307A (zh) 2023-02-03

Similar Documents

Publication Publication Date Title
JP7797425B2 (ja) ダプロデュスタットを含んでなる処方物
MX2012000892A (es) Formas de dosificacion de citrato ferrico.
EP2068835A2 (en) Imatinib compositions
US20250249015A1 (en) Novel rivaroxaban formulation
US20210290639A1 (en) Immediate release formulation of a triple combination of active pharmaceutical ingredients useful in the treatment of polycystic ovary syndrome
TWI903066B (zh) 包含１－（３－氰基－１－異丙基－吲哚－５－基）吡唑－４－羧酸之口服用複合調配物
CN103284965A (zh) 可生物利用的美他沙酮固体剂型
JP2025039725A (ja) １－（３－シアノ－１－イソプロピル－インドール－５－イル）ピラゾール－４－カルボン酸を含む経口用製剤、およびその製造方法
JP2008534621A (ja) リオチロニンからなる放出制御型医薬組成物、並びにその製造方法及び使用方法
JP5063368B2 (ja) テリスロマイシンを含む固形医薬組成物
WO2022042646A1 (zh) 盐酸鲁拉西酮组合物及其制备方法
WO2022115055A1 (en) Immediate release composition of favipiravir
KR102330953B1 (ko) 소듐-1-[6-(모르폴린-4-일)피리미딘-4-일]-4-(1h-1,2,3-트리아졸-1-일)-1h-피라졸-5-올레이트를 함유하는 제약 투여 형태
RU2321405C2 (ru) Лекарственное средство, обладающее анальгезирующим, жаропонижающим и психостимулирующим действием, и способ его получения
JP2016503782A (ja) Ｎ−［５−［２−（３，５−ジメトキシフェニル）エチル］−２ｈ−ピラゾール−３−イル］−４−［（３ｒ，５ｓ）−３，５−ジメチルピペラジン−１−イル］ベンズアミドの医薬製剤
CN101242841A (zh) 微粉化(4-氯苯基)[4-(4-吡啶基甲基)酞嗪-1-基]及其盐的速释和高载药的药物制剂
EA049988B1 (ru) Лекарственная форма для перорального применения, содержащая 1-(3-циано-1-изопропил-индол-5-ил)пиразол-4-карбоновую кислоту
HK40095918A (zh) 包含1-(3-氰基-1-异丙基-吲哚-5-基)吡唑-4-甲酸的口服制剂及其制备方法
HK40097002A (zh) 含有1-(3-氰基-1-异丙基-吲哚-5-基)吡唑-4-甲酸的口服制剂
WO2022125006A1 (en) High drug load compositions of favipiravir
CN101242840A (zh) 非微粉化(4-氯苯基)[4-(4-吡啶基甲基)酞嗪-1-基]及其盐的速释和高载药的药物制剂
CN108721241A (zh) 一种包含缬沙坦和氨氯地平的固体组合物及其制备方法
WO2017114597A1 (en) Pharmaceutical dosage forms comprising ((cis)-n-(4-(dimethylamino)-1,4- diphenylcyclohexyl)-n-methylcinnamamide
HK1225281B (zh) 包含1-[6-(吗啉-4-基)嘧啶-4-基]-4-(1h-1，2，3-三唑-1-基)-1h-吡唑-5-醇钠的药物剂型

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240610

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20240610

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20250625

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20250704

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20251001

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20251209

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20251224

R150 Certificate of patent or registration of utility model

Ref document number: 7797425

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150