JP7790724B2 - 発光基質化合物 - Google Patents

発光基質化合物

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Publication number
JP7790724B2
JP7790724B2 JP2022508414A JP2022508414A JP7790724B2 JP 7790724 B2 JP7790724 B2 JP 7790724B2 JP 2022508414 A JP2022508414 A JP 2022508414A JP 2022508414 A JP2022508414 A JP 2022508414A JP 7790724 B2 JP7790724 B2 JP 7790724B2
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JP
Japan
Prior art keywords
group
formula
solvate
salt
hydrate
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JP2022508414A
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English (en)
Japanese (ja)
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JPWO2021187531A1 (https=
JPWO2021187531A5 (https=
Inventor
諒 西原
僚二 栗田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Institute of Advanced Industrial Science and Technology AIST
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National Institute of Advanced Industrial Science and Technology AIST
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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP2022508414A 2020-03-17 2021-03-17 発光基質化合物 Active JP7790724B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2020046137 2020-03-17
JP2020046137 2020-03-17
PCT/JP2021/010852 WO2021187531A1 (ja) 2020-03-17 2021-03-17 発光基質化合物

Publications (3)

Publication Number Publication Date
JPWO2021187531A1 JPWO2021187531A1 (https=) 2021-09-23
JPWO2021187531A5 JPWO2021187531A5 (https=) 2024-03-07
JP7790724B2 true JP7790724B2 (ja) 2025-12-23

Family

ID=77772109

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022508414A Active JP7790724B2 (ja) 2020-03-17 2021-03-17 発光基質化合物

Country Status (3)

Country Link
US (1) US20230288338A1 (https=)
JP (1) JP7790724B2 (https=)
WO (1) WO2021187531A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024262411A1 (ja) * 2023-06-22 2024-12-26 国立研究開発法人産業技術総合研究所 血清アルブミンの検出剤
WO2025084165A1 (ja) * 2023-10-18 2025-04-24 国立研究開発法人産業技術総合研究所 抗体の変性状態の評価方法
CN118084918A (zh) * 2024-01-29 2024-05-28 中国药科大学 一种化学发光探针及其制备方法和在检测β淀粉样蛋白中的应用
CN121609704A (zh) * 2026-02-02 2026-03-06 浙江大学医学院附属第一医院(浙江省第一医院) 一种对tau蛋白响应的近红外化学发光探针及其制备方法和应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014503485A (ja) 2010-11-02 2014-02-13 プロメガ コーポレイション 新規セレンテラジン基質及び使用法
JP2018158896A (ja) 2017-03-22 2018-10-11 学校法人慶應義塾 新規セレンテラジン化合物及びその用途
JP2018165265A (ja) 2017-03-28 2018-10-25 国立大学法人電気通信大学 新規セレンテラジン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0560697A (ja) * 1991-08-30 1993-03-12 Nippon Oil & Fats Co Ltd スーパーオキシドアニオンの定量方法及びスーパーオキシドアニオン消去物質の定量方法
US9849198B2 (en) * 2013-07-02 2017-12-26 The Board Of Trustees Of The Leland Stanford Junior University Discrete imaging of hepatic oxidative and nitrosative stress with two-channel nanoparticles for in vivo drug safety screening

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2014503485A (ja) 2010-11-02 2014-02-13 プロメガ コーポレイション 新規セレンテラジン基質及び使用法
JP2018158896A (ja) 2017-03-22 2018-10-11 学校法人慶應義塾 新規セレンテラジン化合物及びその用途
JP2018165265A (ja) 2017-03-28 2018-10-25 国立大学法人電気通信大学 新規セレンテラジン誘導体

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Photochemical & Photobiological Sciences，2008年，Vol. 7，pp. 197-207
STN REGISTRY File，RN: 747407-37-0, [online], Entered STN: 19 Sep. 2004, [retrieved on 10 Dec. 2024]
STN REGISTRY File，RN: 767284-57-1, [online], Entered STN: 22 Oct. 2004, [retrieved on 10 Dec. 2024]
久保田 英博，食品成分の簡便かつ高感度な抗酸化能測定システムの開発，食品産業センター技術研究報告，2001年，Vol. 27，p.47-56，ISSN: 0388-3388

Also Published As

Publication number Publication date
JPWO2021187531A1 (https=) 2021-09-23
WO2021187531A1 (ja) 2021-09-23
US20230288338A1 (en) 2023-09-14

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