JP7788711B2 - 複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法 - Google Patents

複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法

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JP7788711B2
JP7788711B2 JP2020525826A JP2020525826A JP7788711B2 JP 7788711 B2 JP7788711 B2 JP 7788711B2 JP 2020525826 A JP2020525826 A JP 2020525826A JP 2020525826 A JP2020525826 A JP 2020525826A JP 7788711 B2 JP7788711 B2 JP 7788711B2
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cells
antibody
positive
antigen
anergy
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JPWO2019245038A1 (ja
JPWO2019245038A5 (https=
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浩一郎 内田
和由 竹田
康 奥村
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Junten Bio Co Ltd
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    • GPHYSICS
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6854Immunoglobulins
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K40/00Cellular immunotherapy
    • A61K40/10Cellular immunotherapy characterised by the cell type used
    • A61K40/11T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/20Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/22Immunosuppressive or immunotolerising
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/418Antigens related to induction of tolerance to non-self
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00Cellular immunotherapy
    • A61K40/40Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41Vertebrate antigens
    • A61K40/42Cancer antigens
    • A61K40/4202Receptors, cell surface antigens or cell surface determinants
    • A61K40/421Immunoglobulin superfamily
    • A61K40/4211CD19 or B4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
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JP2020525826A 2018-06-22 2019-06-21 複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法 Active JP7788711B2 (ja)

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JP2023209708A JP2024015377A (ja) 2018-06-22 2023-12-12 複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法

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JP2018119001 2018-06-22
JP2018119001 2018-06-22
PCT/JP2019/024753 WO2019245038A1 (ja) 2018-06-22 2019-06-21 複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法

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JP2023209708A Division JP2024015377A (ja) 2018-06-22 2023-12-12 複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法

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JPWO2019245038A1 JPWO2019245038A1 (ja) 2021-07-08
JPWO2019245038A5 JPWO2019245038A5 (https=) 2022-06-21
JP7788711B2 true JP7788711B2 (ja) 2025-12-19

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JP2023209708A Pending JP2024015377A (ja) 2018-06-22 2023-12-12 複合状態を有する細胞混合物を用いた、免疫寛容を誘導する抗体、及び誘導されたリンパ球、また誘導されたリンパ球を用いる細胞治療剤及び治療法

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US (1) US12397054B2 (https=)
EP (1) EP3811952A4 (https=)
JP (2) JP7788711B2 (https=)
KR (2) KR20210024048A (https=)
CN (1) CN112601531A (https=)
AU (1) AU2019288683A1 (https=)
CA (1) CA3104797A1 (https=)
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JP2005530762A (ja) 2002-05-06 2005-10-13 バイオマリン ファーマシューティカル インコーポレイテッド 抗原特異的免疫学的寛容性の誘導
JP2011500730A (ja) 2007-10-26 2011-01-06 ガバニング カウンセル オブ ザ ユニバーシティ オブ トロント Tim−3を用いた治療および診断方法
JP2011502163A (ja) 2007-10-31 2011-01-20 ザ スクリプス リサーチ インスティテュート 持続性ウイルス感染を治療するための併用療法
JP2023033175A (ja) 2021-08-26 2023-03-09 日星電気株式会社 発熱部材の保護構造、及び液体処理装置

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JP2011500730A (ja) 2007-10-26 2011-01-06 ガバニング カウンセル オブ ザ ユニバーシティ オブ トロント Tim−3を用いた治療および診断方法
JP2011502163A (ja) 2007-10-31 2011-01-20 ザ スクリプス リサーチ インスティテュート 持続性ウイルス感染を治療するための併用療法
JP2023033175A (ja) 2021-08-26 2023-03-09 日星電気株式会社 発熱部材の保護構造、及び液体処理装置

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WO2019245038A1 (ja) 2019-12-26
TWI832869B (zh) 2024-02-21
AU2019288683A1 (en) 2021-01-21
JP2024015377A (ja) 2024-02-01
EP3811952A4 (en) 2022-06-01
JPWO2019245038A1 (ja) 2021-07-08
CA3104797A1 (en) 2019-12-26
US12397054B2 (en) 2025-08-26
US20210260124A1 (en) 2021-08-26
TW202015710A (zh) 2020-05-01
CN112601531A (zh) 2021-04-02
KR20250096878A (ko) 2025-06-27
KR20210024048A (ko) 2021-03-04
EP3811952A1 (en) 2021-04-28

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