JP7788128B2 - 呼吸器疾患の治療のための化合物 - Google Patents

呼吸器疾患の治療のための化合物

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Publication number
JP7788128B2
JP7788128B2 JP2019560254A JP2019560254A JP7788128B2 JP 7788128 B2 JP7788128 B2 JP 7788128B2 JP 2019560254 A JP2019560254 A JP 2019560254A JP 2019560254 A JP2019560254 A JP 2019560254A JP 7788128 B2 JP7788128 B2 JP 7788128B2
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JP
Japan
Prior art keywords
mmol
cycloalkyl
solvate
salt
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2019560254A
Other languages
English (en)
Japanese (ja)
Other versions
JP2020518621A (ja
JPWO2018201192A5 (enExample
JP2020518621A5 (enExample
Inventor
ウィリアムズ、スペンサー
シャー、サヤリ
ハッキ、ザリヘ
スチュワート、アラステア
Original Assignee
ティアンリ バイオテック プロプライエタリ リミテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2017901611A external-priority patent/AU2017901611A0/en
Application filed by ティアンリ バイオテック プロプライエタリ リミテッド filed Critical ティアンリ バイオテック プロプライエタリ リミテッド
Publication of JP2020518621A publication Critical patent/JP2020518621A/ja
Publication of JP2020518621A5 publication Critical patent/JP2020518621A5/ja
Priority to JP2023101906A priority Critical patent/JP2023134493A/ja
Publication of JPWO2018201192A5 publication Critical patent/JPWO2018201192A5/ja
Application granted granted Critical
Publication of JP7788128B2 publication Critical patent/JP7788128B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP2019560254A 2017-05-03 2018-05-03 呼吸器疾患の治療のための化合物 Active JP7788128B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2023101906A JP2023134493A (ja) 2017-05-03 2023-06-21 呼吸器疾患の治療のための化合物

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AU2017901611A AU2017901611A0 (en) 2017-05-03 Compounds for the treatment of respiratory diseases
AU2017901611 2017-05-03
AU2017901647A AU2017901647A0 (en) 2017-05-05 Compounds for the treatment of respiratory diseases
AU2017901647 2017-05-05
PCT/AU2018/050404 WO2018201192A1 (en) 2017-05-03 2018-05-03 Compounds for the treatment of respiratory diseases

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2023101906A Division JP2023134493A (ja) 2017-05-03 2023-06-21 呼吸器疾患の治療のための化合物

Publications (4)

Publication Number Publication Date
JP2020518621A JP2020518621A (ja) 2020-06-25
JP2020518621A5 JP2020518621A5 (enExample) 2021-05-27
JPWO2018201192A5 JPWO2018201192A5 (enExample) 2025-04-14
JP7788128B2 true JP7788128B2 (ja) 2025-12-18

Family

ID=64015663

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2019560254A Active JP7788128B2 (ja) 2017-05-03 2018-05-03 呼吸器疾患の治療のための化合物
JP2023101906A Withdrawn JP2023134493A (ja) 2017-05-03 2023-06-21 呼吸器疾患の治療のための化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2023101906A Withdrawn JP2023134493A (ja) 2017-05-03 2023-06-21 呼吸器疾患の治療のための化合物

Country Status (9)

Country Link
US (2) US20200079757A1 (enExample)
EP (1) EP3619204B1 (enExample)
JP (2) JP7788128B2 (enExample)
CN (1) CN110753688A (enExample)
AU (3) AU2018262108A1 (enExample)
ES (1) ES3049333T3 (enExample)
FI (1) FI3619204T3 (enExample)
PT (1) PT3619204T (enExample)
WO (1) WO2018201192A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113350352B (zh) 2015-03-23 2024-09-10 天莅生物科技私人有限公司 呼吸性疾病的治疗
WO2020093097A1 (en) * 2018-11-07 2020-05-14 The University Of Melbourne Compounds and compositions for the treatment of respiratory diseases
CN110452880B (zh) * 2019-09-09 2021-09-21 温州医科大学附属第一医院 急性肺损伤细胞模型的制备方法及其应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016149756A1 (en) 2015-03-23 2016-09-29 The University Of Melbourne Treatment of respiratory diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL110296A (en) * 1993-07-16 1999-12-31 Smithkline Beecham Corp Imidazole compounds process for their preparation and pharmaceutical compositions containing them
US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
US5593991A (en) * 1993-07-16 1997-01-14 Adams; Jerry L. Imidazole compounds, use and process of making
IL118544A (en) * 1995-06-07 2001-08-08 Smithkline Beecham Corp History of imidazole, the process for their preparation and the pharmaceutical preparations containing them
CA2314980A1 (en) * 1997-12-19 1999-07-01 Smithkline Beecham Corporation Compounds of heteroaryl substituted imidazole, their pharmaceutical compositions and uses
IN2012DN03182A (enExample) * 2009-10-28 2015-09-25 Pfizer
CZ2012538A3 (cs) * 2012-08-08 2014-02-19 Masarykova Univerzita Inhibitory pro léčbu B-buněčné chronické lymfocytární leukémie

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016149756A1 (en) 2015-03-23 2016-09-29 The University Of Melbourne Treatment of respiratory diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Bioorganic & Medicinal Chemistry Letters, 2008, Vol. 18, p. 4006-4010

Also Published As

Publication number Publication date
CN110753688A (zh) 2020-02-04
EP3619204A1 (en) 2020-03-11
JP2020518621A (ja) 2020-06-25
FI3619204T3 (fi) 2025-11-06
US20200079757A1 (en) 2020-03-12
EP3619204A4 (en) 2021-03-24
AU2024200521B2 (en) 2025-10-02
US20220380343A1 (en) 2022-12-01
WO2018201192A1 (en) 2018-11-08
JP2023134493A (ja) 2023-09-27
PT3619204T (pt) 2025-10-29
AU2024200521A1 (en) 2024-02-15
AU2022202774A1 (en) 2022-05-19
EP3619204B1 (en) 2025-10-01
ES3049333T3 (en) 2025-12-16
AU2018262108A1 (en) 2019-11-21

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