JP7707065B2 - Ａｎｇｐｔｌ８を阻害するための新規のｒｎａ組成物および方法 - Google Patents

Ａｎｇｐｔｌ８を阻害するための新規のｒｎａ組成物および方法 Download PDF

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JP7707065B2
JP7707065B2 JP2021528936A JP2021528936A JP7707065B2 JP 7707065 B2 JP7707065 B2 JP 7707065B2 JP 2021528936 A JP2021528936 A JP 2021528936A JP 2021528936 A JP2021528936 A JP 2021528936A JP 7707065 B2 JP7707065 B2 JP 7707065B2
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dsrna
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angptl8
nucleotides
sequence
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ボードー・ブルナー
マイク・ヘルムス
アルミン・ホフマイスター
ケルスティーン・ヤーン－ホフマン
クリスティアーネ・メッツ－ヴァイドマン
ザビーネ・シャイドラー
ピエリック・リヴァル
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Sanofi SA
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  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2021528936A 2018-11-23 2019-11-22 Ａｎｇｐｔｌ８を阻害するための新規のｒｎａ組成物および方法 Active JP7707065B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18306562 2018-11-23
EP18306562.2 2018-11-23
PCT/EP2019/082216 WO2020104649A2 (en) 2018-11-23 2019-11-22 Novel rna compositions and methods for inhibiting angptl8

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JP2022513111A JP2022513111A (ja) 2022-02-07
JP2022513111A5 JP2022513111A5 (https=) 2022-11-29
JPWO2020104649A5 JPWO2020104649A5 (https=) 2022-11-29
JP7707065B2 true JP7707065B2 (ja) 2025-07-14

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US (1) US12416004B2 (https=)
EP (1) EP3884051A2 (https=)
JP (1) JP7707065B2 (https=)
CN (1) CN113166760A (https=)
WO (1) WO2020104649A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3884051A2 (en) 2018-11-23 2021-09-29 Sanofi Novel rna compositions and methods for inhibiting angptl8
JP7667775B2 (ja) * 2019-09-05 2025-04-23 サノフイ ヌクレオチド類似体を含有するオリゴヌクレオチド
CA3224145A1 (en) 2021-06-24 2022-12-29 Melissa Ann Bellinger Novel rna therapeutics and uses thereof
WO2024138111A1 (en) 2022-12-23 2024-06-27 Eli Lilly And Company Novel rna therapeutics and uses thereof
CN118421622A (zh) * 2023-02-01 2024-08-02 北京福元医药股份有限公司 抑制血管生成素样蛋白8基因表达的siRNA、其缀合物和药物组合物及用途
WO2024227059A2 (en) * 2023-04-27 2024-10-31 Aligos Therapeutics, Inc. Short interfering nucleic acid (sina) molecules targeting angptl 3 and angptl 8 and methods of using the same
WO2025264952A2 (en) 2024-06-21 2025-12-26 Eli Lilly And Company Novel rna therapeutics and uses thereof
CN119367545B (zh) * 2025-01-02 2025-04-08 山东第一医科大学(山东省医学科学院) 靶向干预ANGPTL8 mRNA在制备治疗高同型半胱氨酸血症药物中的应用

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Also Published As

Publication number Publication date
EP3884051A2 (en) 2021-09-29
US20220025367A1 (en) 2022-01-27
WO2020104649A2 (en) 2020-05-28
CN113166760A (zh) 2021-07-23
WO2020104649A3 (en) 2020-07-02
US12416004B2 (en) 2025-09-16
JP2022513111A (ja) 2022-02-07

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