JP7670618B2 - 環状ペプチド抗生物質 - Google Patents

環状ペプチド抗生物質 Download PDF

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Publication number
JP7670618B2
JP7670618B2 JP2021553777A JP2021553777A JP7670618B2 JP 7670618 B2 JP7670618 B2 JP 7670618B2 JP 2021553777 A JP2021553777 A JP 2021553777A JP 2021553777 A JP2021553777 A JP 2021553777A JP 7670618 B2 JP7670618 B2 JP 7670618B2
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optionally substituted
alkyl
mmol
heterocycloalkyl
cycloalkyl
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Japanese (ja)
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JP2022524151A5 (https=
JP2022524151A (ja
JPWO2020185999A5 (https=
Inventor
クオション ウー，
エミリー ジェー． ハナン，
マリー－ガブリエル ブラウン，
シャーラダー ラバディ，
ケイラ ガーランド，
リチャード エム． パスター，
ポール ギボンズ，
ユイホン フー，
ユンシン チョン，
Original Assignee
エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
JP2021553777A 2019-03-14 2020-03-12 環状ペプチド抗生物質 Active JP7670618B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024203544A JP2025037920A (ja) 2019-03-14 2024-11-21 環状ペプチド抗生物質

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CN2019078189 2019-03-14
CNPCT/CN2019/078189 2019-03-14
PCT/US2020/022272 WO2020185999A1 (en) 2019-03-14 2020-03-12 Cyclic peptide antibiotics

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024203544A Division JP2025037920A (ja) 2019-03-14 2024-11-21 環状ペプチド抗生物質

Publications (4)

Publication Number Publication Date
JP2022524151A JP2022524151A (ja) 2022-04-27
JP2022524151A5 JP2022524151A5 (https=) 2023-03-22
JPWO2020185999A5 JPWO2020185999A5 (https=) 2023-03-22
JP7670618B2 true JP7670618B2 (ja) 2025-04-30

Family

ID=70190176

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021553777A Active JP7670618B2 (ja) 2019-03-14 2020-03-12 環状ペプチド抗生物質
JP2024203544A Pending JP2025037920A (ja) 2019-03-14 2024-11-21 環状ペプチド抗生物質

Family Applications After (1)

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JP2024203544A Pending JP2025037920A (ja) 2019-03-14 2024-11-21 環状ペプチド抗生物質

Country Status (5)

Country Link
US (1) US12358951B2 (https=)
EP (1) EP3938377A1 (https=)
JP (2) JP7670618B2 (https=)
CN (1) CN113710687A (https=)
WO (1) WO2020185999A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025037920A (ja) * 2019-03-14 2025-03-18 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 環状ペプチド抗生物質

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022009212A1 (en) * 2020-07-09 2022-01-13 Technion Research And Development Foundation Ltd. TYROSINE, TRYPTOPHAN AND PHENYLALANINE AS mTOR AGONISTS MEDIATING PROTEASOME DYNAMICS, COMPOSITIONS, METHODS AND USES THEREOF IN THERAPY, AND PROGNOSTIC METHODS FOR DRUG-RESISTANCE
CN118307583A (zh) * 2024-04-03 2024-07-09 上海科技大学 β氨基酯、聚β氨基酯化合物及其制备方法及应用

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017079820A1 (en) 2015-11-11 2017-05-18 Encycle Therapeutics, Inc. CYCLIC PEPTIDES TARGETING α4β7 INTEGRIN
WO2019052545A1 (en) 2017-09-15 2019-03-21 F. Hoffmann-La Roche Ag CYCLIC PEPTIDE ANTIBIOTICS

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS594990B2 (ja) 1977-05-13 1984-02-02 三共株式会社 抗生物質グロボマイシン
JPS5547644A (en) 1978-10-02 1980-04-04 Meiji Seika Kaisha Ltd New antibiotics sf-1902 a2, a3, a4 and a5 and their preparation
US5384309A (en) 1989-07-17 1995-01-24 Genentech, Inc. Cyclized peptides and their use as platelet aggregation inhibitors
US10787490B2 (en) 2015-07-15 2020-09-29 Protaganist Therapeutics, Inc. Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases
WO2020185999A1 (en) * 2019-03-14 2020-09-17 Genentech, Inc. Cyclic peptide antibiotics

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017079820A1 (en) 2015-11-11 2017-05-18 Encycle Therapeutics, Inc. CYCLIC PEPTIDES TARGETING α4β7 INTEGRIN
WO2019052545A1 (en) 2017-09-15 2019-03-21 F. Hoffmann-La Roche Ag CYCLIC PEPTIDE ANTIBIOTICS

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Bioorganic & Medicinal Chemistry Letters，2003年，Vol. 13，pp. 2315-2318
Bioorganic & Medicinal Chemistry，2004年，Vol. 12，pp. 337-361
Science，2016年，Vol. 351, Issue 6275，pp. 876-880
有機合成化学協会誌，2005年，Vol. 63, No. 1，pp. 51-62

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025037920A (ja) * 2019-03-14 2025-03-18 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト 環状ペプチド抗生物質

Also Published As

Publication number Publication date
EP3938377A1 (en) 2022-01-19
JP2022524151A (ja) 2022-04-27
US12358951B2 (en) 2025-07-15
WO2020185999A1 (en) 2020-09-17
JP2025037920A (ja) 2025-03-18
US20230025834A1 (en) 2023-01-26
CN113710687A (zh) 2021-11-26

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