JP7665621B2 - ベンゾチアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 - Google Patents

ベンゾチアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 Download PDF

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Publication number
JP7665621B2
JP7665621B2 JP2022532833A JP2022532833A JP7665621B2 JP 7665621 B2 JP7665621 B2 JP 7665621B2 JP 2022532833 A JP2022532833 A JP 2022532833A JP 2022532833 A JP2022532833 A JP 2022532833A JP 7665621 B2 JP7665621 B2 JP 7665621B2
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tetrahydro
dioxide
benzothiazepin
oxy
acetic acid
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Japanese (ja)
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JP2023504646A5 (https=
JP2023504646A (ja
JPWO2021110887A5 (https=
Inventor
ペル－ヨーラン・ギルベリ
インゲマル・スタルケ
サントシュ・エス・クルカルニ
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アルビレオ・アクチボラグ
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Priority claimed from PCT/EP2020/084571 external-priority patent/WO2021110887A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2022532833A 2019-12-04 2020-12-04 ベンゾチアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用 Active JP7665621B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN201911049985 2019-12-04
IN201911049985 2019-12-04
PCT/EP2020/084571 WO2021110887A1 (en) 2019-12-04 2020-12-04 Benzothiazepine compounds and their use as bile acid modulators

Publications (4)

Publication Number Publication Date
JP2023504646A JP2023504646A (ja) 2023-02-06
JP2023504646A5 JP2023504646A5 (https=) 2023-12-05
JPWO2021110887A5 JPWO2021110887A5 (https=) 2023-12-05
JP7665621B2 true JP7665621B2 (ja) 2025-04-21

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ID=82196618

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JP2022532833A Active JP7665621B2 (ja) 2019-12-04 2020-12-04 ベンゾチアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用

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EP (1) EP4069362A1 (https=)
JP (1) JP7665621B2 (https=)
CN (1) CN114786773B (https=)
CA (1) CA3158175A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4188541B1 (en) * 2020-08-03 2024-12-25 Albireo AB Benzothia(di)azepine compounds and their use as bile acid modulators

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004516285A (ja) 2000-12-21 2004-06-03 アストラゼネカ アクチボラグ １，５ベンゾチアゼピン及び抗高脂質血症剤としてのその使用
JP2005505554A (ja) 2001-09-04 2005-02-24 アストラゼネカ アクチボラグ ベンゾチアゼピン誘導体

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9800428D0 (en) * 1998-01-10 1998-03-04 Glaxo Group Ltd Chemical compounds
JP6097695B2 (ja) * 2010-11-08 2017-03-15 アルビレオ アクチエボラグ Ｉｂａｔ阻害剤および胆汁酸結合剤を含む薬学的組み合わせ

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004516285A (ja) 2000-12-21 2004-06-03 アストラゼネカ アクチボラグ １，５ベンゾチアゼピン及び抗高脂質血症剤としてのその使用
JP2005505554A (ja) 2001-09-04 2005-02-24 アストラゼネカ アクチボラグ ベンゾチアゼピン誘導体

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Publication number Publication date
EP4069362A1 (en) 2022-10-12
CN114786773B (zh) 2024-10-18
JP2023504646A (ja) 2023-02-06
CA3158175A1 (en) 2021-06-10
CN114786773A (zh) 2022-07-22

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