JP7651470B2 - 核酸を解析するための方法および組成物 - Google Patents

核酸を解析するための方法および組成物 Download PDF

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JP7651470B2
JP7651470B2 JP2021559245A JP2021559245A JP7651470B2 JP 7651470 B2 JP7651470 B2 JP 7651470B2 JP 2021559245 A JP2021559245 A JP 2021559245A JP 2021559245 A JP2021559245 A JP 2021559245A JP 7651470 B2 JP7651470 B2 JP 7651470B2
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scaffold
nucleic acid
ssna
oligonucleotide
hybridization
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JP2022528139A5 (https=
JPWO2020206143A5 (https=
JP2022528139A (ja
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キンケイド， ケリー エム． ハーキンズ
コリン パトリック ノートン，
ヴァーシャ ラオ，
クリストファー ジェイ． トロル，
ジョシュア ディー． カップ，
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クラレット バイオサイエンス， エルエルシー
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1093—General methods of preparing gene libraries, not provided for in other subgroups
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1068—Template (nucleic acid) mediated chemical library synthesis, e.g. chemical and enzymatical DNA-templated organic molecule synthesis, libraries prepared by non ribosomal polypeptide synthesis [NRPS], DNA/RNA-polymerase mediated polypeptide synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2330/00—Production
    • C12N2330/30—Production chemically synthesised
    • C12N2330/31—Libraries, arrays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2021559245A 2019-04-05 2020-04-02 核酸を解析するための方法および組成物 Active JP7651470B2 (ja)

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JP2024189679A JP2025014018A (ja) 2019-04-05 2024-10-29 核酸を解析するための方法および組成物

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US201962830211P 2019-04-05 2019-04-05
US62/830,211 2019-04-05
US201962861594P 2019-06-14 2019-06-14
US62/861,594 2019-06-14
US201962925132P 2019-10-23 2019-10-23
US62/925,132 2019-10-23
PCT/US2020/026421 WO2020206143A1 (en) 2019-04-05 2020-04-02 Methods and compositions for analyzing nucleic acid

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JP2022528139A JP2022528139A (ja) 2022-06-08
JP2022528139A5 JP2022528139A5 (https=) 2023-03-13
JPWO2020206143A5 JPWO2020206143A5 (https=) 2023-03-13
JP7651470B2 true JP7651470B2 (ja) 2025-03-26

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EP (2) EP4538390A3 (https=)
JP (2) JP7651470B2 (https=)
KR (1) KR20210148304A (https=)
CN (1) CN114174530A (https=)
AU (1) AU2020253471A1 (https=)
CA (1) CA3134831A1 (https=)
IL (1) IL286945A (https=)
SG (1) SG11202110468YA (https=)
WO (1) WO2020206143A1 (https=)

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CN121344163A (zh) * 2020-01-16 2026-01-16 Dnae诊断有限公司 用于分离靶多核苷酸的组合物、试剂盒和方法
CA3186974A1 (en) * 2020-06-24 2021-12-30 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
WO2022020346A1 (en) 2020-07-21 2022-01-27 Claret Bioscience, Llc Cancer detection, monitoring, and reporting from sequencing cell-free dna
US20240395358A1 (en) 2020-10-08 2024-11-28 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
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CN118401675A (zh) * 2021-10-15 2024-07-26 凯杰科学有限责任公司 制备dna文库的方法及其用途
WO2023158739A2 (en) * 2022-02-17 2023-08-24 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
US20260078439A1 (en) * 2022-08-24 2026-03-19 The Regents Of The University Of California Next-Generation Sequencing Pipeline for Detection of Ultrashort Single-Stranded Cell-Free DNA
WO2024054517A1 (en) * 2022-09-08 2024-03-14 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
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CN119998463A (zh) * 2023-03-20 2025-05-13 深圳华大智造科技股份有限公司 一种高效且快速进行核酸文库构建的方法
WO2024254073A1 (en) * 2023-06-07 2024-12-12 Claret Bioscience, Llc Methods and compositions for analyzing nucleic acid
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WO2026058704A1 (ja) * 2024-09-10 2026-03-19 国立大学法人 東京大学 Ｄｎａバーコード配列を含む一本鎖 ｄｎａの合成方法（ｍｅｔｈｏｄ ｆｏｒ ｓｙｎｔｈｅｓｉｚｉｎｇ ｓｉｎｇｌｅ－ｓｔｒａｎｄｅｄ ｄｎａ ｃｏｎｔａｉｎｉｎｇ ｄｎａ ｂａｒｃｏｄｅ ｓｅｑｕｅｎｃｅｓ）

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Publication number Publication date
JP2025014018A (ja) 2025-01-28
IL286945A (en) 2021-12-01
KR20210148304A (ko) 2021-12-07
AU2020253471A1 (en) 2021-10-14
SG11202110468YA (en) 2021-10-28
EP3947723C0 (en) 2024-12-18
CN114174530A (zh) 2022-03-11
WO2020206143A1 (en) 2020-10-08
EP3947723B1 (en) 2024-12-18
EP3947723A1 (en) 2022-02-09
WO2020206143A9 (en) 2021-12-23
EP4538390A2 (en) 2025-04-16
CA3134831A1 (en) 2020-10-08
EP4538390A3 (en) 2025-07-09
US20220348906A1 (en) 2022-11-03
JP2022528139A (ja) 2022-06-08

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