JP7634895B2 - パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物 - Google Patents

パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物 Download PDF

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JP7634895B2
JP7634895B2 JP2022522035A JP2022522035A JP7634895B2 JP 7634895 B2 JP7634895 B2 JP 7634895B2 JP 2022522035 A JP2022522035 A JP 2022522035A JP 2022522035 A JP2022522035 A JP 2022522035A JP 7634895 B2 JP7634895 B2 JP 7634895B2
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JP2022551943A (ja
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ピーター ノヴァク，
マキシム テムニコフ，
オレクサンドル バラキン，
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ヴェクター ヴィターレ アイピー エルエルシー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/18—Sulfonamides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/14—Alkali metal chlorides; Alkaline earth metal chlorides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP2022522035A 2019-10-11 2019-10-11 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物 Active JP7634895B2 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2024000684A JP2024038270A (ja) 2019-10-11 2024-01-05 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2025113738A JP2025148408A (ja) 2019-10-11 2025-07-04 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2025202951A JP2026035686A (ja) 2019-10-11 2025-11-25 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2019/055770 WO2021071499A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Related Child Applications (1)

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JP2024000684A Division JP2024038270A (ja) 2019-10-11 2024-01-05 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物

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JP2022551943A JP2022551943A (ja) 2022-12-14
JP7634895B2 true JP7634895B2 (ja) 2025-02-25

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JP2022522035A Active JP7634895B2 (ja) 2019-10-11 2019-10-11 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2024000684A Withdrawn JP2024038270A (ja) 2019-10-11 2024-01-05 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2025113738A Pending JP2025148408A (ja) 2019-10-11 2025-07-04 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2025202951A Pending JP2026035686A (ja) 2019-10-11 2025-11-25 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物

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JP2024000684A Withdrawn JP2024038270A (ja) 2019-10-11 2024-01-05 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2025113738A Pending JP2025148408A (ja) 2019-10-11 2025-07-04 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物
JP2025202951A Pending JP2026035686A (ja) 2019-10-11 2025-11-25 パーキンソン病およびその他の神経変性疾患を処置するためのルビジウムおよび／または亜鉛化合物

Country Status (6)

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US (2) US11779597B2 (https=)
EP (1) EP4041214A1 (https=)
JP (4) JP7634895B2 (https=)
AU (1) AU2019470001B2 (https=)
CA (2) CA3154392A1 (https=)
WO (1) WO2021071499A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116077524A (zh) * 2023-02-27 2023-05-09 广西馨海药业科技有限公司 氯化铷在制备治疗帕金森综合征的药物中的用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015185602A1 (en) 2014-06-04 2015-12-10 Affiris Ag Treatment and prevention of parkinson's disease (pd)
US10226484B2 (en) 2014-12-01 2019-03-12 Peter Y Novak Pharmaceutical composition for improving health, cure abnormalities and degenerative disease, achieve anti-aging effect of therapy and therapeutic effect on mammals and method thereof

Family Cites Families (9)

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Publication number Priority date Publication date Assignee Title
EP0472053B1 (en) * 1990-08-20 1998-06-17 Eisai Co., Ltd. Sulfonamide derivatives
JP2790926B2 (ja) * 1990-08-20 1998-08-27 エーザイ株式会社 スルホンアミド誘導体
US6162350A (en) 1997-07-15 2000-12-19 Exxon Research And Engineering Company Hydroprocessing using bulk Group VIII/Group VIB catalysts (HEN-9901)
US20160153957A1 (en) 2014-12-01 2016-06-02 Peter Y. Novak Method for diagnostics of pathology in biologocal objects
JP7003045B2 (ja) * 2016-02-11 2022-02-04 シェヴィオン モデハイ 神経変性の治療のための方法及び医薬組成物
CN106581056A (zh) * 2016-10-11 2017-04-26 徐志强 锌在制造治疗帕金森病药物的用途
US10183041B2 (en) 2017-04-12 2019-01-22 Vector Vitale Ip Llc Antibacterial composition and its use in treating bacterial infections
US10799530B1 (en) 2019-12-20 2020-10-13 Vector Vitale Ip Llc Composition and method for the prevention and treatment of obesity
US10933091B1 (en) 2019-12-20 2021-03-02 Vector Vitale Ip Llc Composition and method for the treatment of type I diabetes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015185602A1 (en) 2014-06-04 2015-12-10 Affiris Ag Treatment and prevention of parkinson's disease (pd)
US10226484B2 (en) 2014-12-01 2019-03-12 Peter Y Novak Pharmaceutical composition for improving health, cure abnormalities and degenerative disease, achieve anti-aging effect of therapy and therapeutic effect on mammals and method thereof

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Publication number Publication date
AU2019470001B2 (en) 2024-09-19
NZ787735A (en) 2025-03-28
WO2021071499A1 (en) 2021-04-15
US11779597B2 (en) 2023-10-10
JP2022551943A (ja) 2022-12-14
JP2024038270A (ja) 2024-03-19
US20240173350A1 (en) 2024-05-30
CA3293959A1 (en) 2026-03-02
AU2019470001A1 (en) 2022-05-12
US12036238B2 (en) 2024-07-16
JP2025148408A (ja) 2025-10-07
JP2026035686A (ja) 2026-03-04
US20230210894A1 (en) 2023-07-06
EP4041214A1 (en) 2022-08-17
CA3154392A1 (en) 2021-04-15

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