CA3293959A1 - Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases - Google Patents

Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Info

Publication number
CA3293959A1
CA3293959A1 CA3293959A CA3293959A CA3293959A1 CA 3293959 A1 CA3293959 A1 CA 3293959A1 CA 3293959 A CA3293959 A CA 3293959A CA 3293959 A CA3293959 A CA 3293959A CA 3293959 A1 CA3293959 A1 CA 3293959A1
Authority
CA
Canada
Prior art keywords
rubidium
neurodegenerative diseases
zinc compounds
treating parkinson
parkinson
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CA3293959A
Other languages
English (en)
Inventor
Peter Novak
Maxim Temnikov
Oleksandr Balakin
Original Assignee
Nomax Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nomax Therapeutics Inc filed Critical Nomax Therapeutics Inc
Priority to CA3293959A priority Critical patent/CA3293959A1/en
Publication of CA3293959A1 publication Critical patent/CA3293959A1/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • A61K31/18Sulfonamides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/14Alkali metal chlorides; Alkaline earth metal chlorides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • A61K33/30Zinc; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/541Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA3293959A 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases Pending CA3293959A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3293959A CA3293959A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CA3293959A CA3293959A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases
CA3154392A CA3154392A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases
PCT/US2019/055770 WO2021071499A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CA3154392A Division CA3154392A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Publications (1)

Publication Number Publication Date
CA3293959A1 true CA3293959A1 (en) 2026-03-02

Family

ID=68387423

Family Applications (2)

Application Number Title Priority Date Filing Date
CA3293959A Pending CA3293959A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases
CA3154392A Pending CA3154392A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3154392A Pending CA3154392A1 (en) 2019-10-11 2019-10-11 Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases

Country Status (6)

Country Link
US (2) US11779597B2 (https=)
EP (1) EP4041214A1 (https=)
JP (4) JP7634895B2 (https=)
AU (1) AU2019470001B2 (https=)
CA (2) CA3293959A1 (https=)
WO (1) WO2021071499A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116077524A (zh) * 2023-02-27 2023-05-09 广西馨海药业科技有限公司 氯化铷在制备治疗帕金森综合征的药物中的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2790926B2 (ja) * 1990-08-20 1998-08-27 エーザイ株式会社 スルホンアミド誘導体
DE69129611T2 (de) 1990-08-20 1998-12-17 Eisai Co., Ltd., Tokio/Tokyo Sulfonamid-Derivate
US6162350A (en) 1997-07-15 2000-12-19 Exxon Research And Engineering Company Hydroprocessing using bulk Group VIII/Group VIB catalysts (HEN-9901)
WO2015185602A1 (en) 2014-06-04 2015-12-10 Affiris Ag Treatment and prevention of parkinson's disease (pd)
US9861659B2 (en) 2014-12-01 2018-01-09 Vector Vitale Ip Llc Pharmaceutical composition for improving health, cure abnormalities and degenerative disease, achieve anti-aging effect of therapy and therapeutic effect on mammals and method thereof
US10226484B2 (en) 2014-12-01 2019-03-12 Peter Y Novak Pharmaceutical composition for improving health, cure abnormalities and degenerative disease, achieve anti-aging effect of therapy and therapeutic effect on mammals and method thereof
MX2018009662A (es) * 2016-02-11 2018-09-11 Chevion Mordechai Metodo y composicion farmaceutica para tratamiento de neurodegeneracion.
CN106581056A (zh) * 2016-10-11 2017-04-26 徐志强 锌在制造治疗帕金森病药物的用途
US10183041B2 (en) 2017-04-12 2019-01-22 Vector Vitale Ip Llc Antibacterial composition and its use in treating bacterial infections
US10933091B1 (en) 2019-12-20 2021-03-02 Vector Vitale Ip Llc Composition and method for the treatment of type I diabetes
US10799530B1 (en) 2019-12-20 2020-10-13 Vector Vitale Ip Llc Composition and method for the prevention and treatment of obesity

Also Published As

Publication number Publication date
NZ787735A (en) 2025-03-28
JP2022551943A (ja) 2022-12-14
AU2019470001B2 (en) 2024-09-19
AU2019470001A1 (en) 2022-05-12
US11779597B2 (en) 2023-10-10
JP2026035686A (ja) 2026-03-04
CA3154392A1 (en) 2021-04-15
EP4041214A1 (en) 2022-08-17
JP7634895B2 (ja) 2025-02-25
JP2025148408A (ja) 2025-10-07
JP2024038270A (ja) 2024-03-19
US20230210894A1 (en) 2023-07-06
US20240173350A1 (en) 2024-05-30
WO2021071499A1 (en) 2021-04-15
US12036238B2 (en) 2024-07-16

Similar Documents

Publication Publication Date Title
CA3297266A1 (en) Compounds for the treatment of neurodegenerative and metabolic disorders
EP3781564A4 (en) Compounds for the treatment of cancer
HK1252425A1 (zh) 用於治疗脱髓鞘疾病的三唑类药物
EP3261446A4 (en) Methods and compositions for the treatment or prevention of parkinson's disease
PL3761982T3 (pl) Zastosowanie nalfurafiny w leczeniu chorób demielinizacyjnych
EP3970710A4 (en) PHARMACEUTICAL COMPOSITION FOR THE PREVENTION OR TREATMENT OF DEGENERATIVE BRAIN DISEASES BY ACTIVATION OF AUTOPHAGY
CA3293959A1 (en) Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases
EP3813872A4 (en) COMPOSITIONS FOR THE TREATMENT OF SKIN CONDITIONS
HK40071799A (en) Rubidium and/or zinc compounds for treating parkinson's and other neurodegenerative diseases
EP3707507A4 (en) METHOD OF PREDICTING THE TREATMENT OF PARKINSON'S MORBUS
EP4010337A4 (en) COMPOSITIONS AND METHODS FOR SUPPRESSING AND/OR TREATING NEURODEGENERATIVE DISEASES AND/OR ASSOCIATED CLINICAL CONDITION
PT3752173T (pt) Combinação de rhodiola e de astragalus para o tratamento de doenças neurodegenerativas.
HK40075186A (en) Cuptsm for the treatment of neurodegenerative disorders
HK40079762A (en) Methods for treating parkinson's disease
EP4072568A4 (en) METHOD FOR TREATING PARKINSON'S DISEASE
HK40061034A (en) Compounds and compositions for the treatment of respiratory diseases
HK40080038A (en) Heteroaryl-biphenyl amides for the treatment of pd-l1 diseases
HK40064369A (en) Compounds for the treatment of kinase-dependent disorders
HK40073332A (en) Methods for the treatment of epilepsy
HK40067779A (en) Compositions and methods of using the same for treatment of neurodegenerative and mitochondrial disease
HK40048106A (en) Compositions and methods for the treatment of parkinson's disease
HK40051477A (en) Heterocyclic compounds for the treatment of epilepsy
AU2018904242A0 (en) Compounds and compositions for the treatment of respiratory diseases
HK40076432A (en) Compounds and methods for treating oxalate-related diseases
HK40072482A (en) Compounds for the treatment of kinase-dependent disorders

Legal Events

Date Code Title Description
A16 Divisional, continuation or continuation in part application filed

Free format text: ST27 STATUS EVENT CODE: A-0-1-A10-A16-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION RECEIVED - DIVISIONAL

Effective date: 20251128

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D11-D117 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION RECEIVED

Effective date: 20251128

MFA Maintenance fee for application paid

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 2ND ANNIV.) - STANDARD

Year of fee payment: 2

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 5TH ANNIV.) - STANDARD

Year of fee payment: 5

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 3RD ANNIV.) - STANDARD

Year of fee payment: 3

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 4TH ANNIV.) - STANDARD

Year of fee payment: 4

Free format text: FEE DESCRIPTION TEXT: MF (APPLICATION, 6TH ANNIV.) - STANDARD

Year of fee payment: 6

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W111 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CORRESPONDENT DETERMINED COMPLIANT

Effective date: 20251128

A00 Application filed

Free format text: ST27 STATUS EVENT CODE: A-1-1-A10-A00-A102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: COMPLIANCE REQUIREMENTS DETERMINED MET

Effective date: 20251231

A18 Application divided or continuation or continuation in part accepted

Free format text: ST27 STATUS EVENT CODE: A-1-1-A10-A18-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: DIVISIONAL REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20251231

D00 Search and/or examination requested or commenced

Free format text: ST27 STATUS EVENT CODE: A-1-1-D10-D00-D118 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: REQUEST FOR EXAMINATION REQUIREMENTS DETERMINED COMPLIANT

Effective date: 20251231

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20251231

W00 Other event occurred

Free format text: ST27 STATUS EVENT CODE: A-1-1-W10-W00-W100 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: LETTER SENT

Effective date: 20260108

D11 Substantive examination requested

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D11-D155 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: ALL REQUIREMENTS FOR EXAMINATION DETERMINED COMPLIANT

Effective date: 20260128

P22 Classification modified

Free format text: ST27 STATUS EVENT CODE: A-1-1-P10-P22-P110 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: CLASSIFICATION MODIFIED

Effective date: 20260128

Q12 Application published

Free format text: ST27 STATUS EVENT CODE: A-2-2-Q10-Q12-X000 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: APPLICATION PUBLISHED (OPEN TO PUBLIC INSPECTION)

Effective date: 20260302