JP7630173B2 - ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 - Google Patents
ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 Download PDFInfo
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- JP7630173B2 JP7630173B2 JP2021539453A JP2021539453A JP7630173B2 JP 7630173 B2 JP7630173 B2 JP 7630173B2 JP 2021539453 A JP2021539453 A JP 2021539453A JP 2021539453 A JP2021539453 A JP 2021539453A JP 7630173 B2 JP7630173 B2 JP 7630173B2
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/4756—Neuregulins, i.e. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1883—Neuregulins, e.g.. p185erbB2 ligands, glial growth factor, heregulin, ARIA, neu differentiation factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2024219524A JP7825894B2 (ja) | 2019-01-07 | 2024-12-16 | ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 |
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910015257.7 | 2019-01-07 | ||
| CN201910015257 | 2019-01-07 | ||
| CN201911412811.1 | 2019-12-31 | ||
| CN201911412811.1A CN111407881A (zh) | 2019-01-07 | 2019-12-31 | 神经调节蛋白用于预防、治疗或延迟心肌损伤的方法和组合物 |
| PCT/CN2020/070299 WO2020143548A1 (zh) | 2019-01-07 | 2020-01-03 | 神经调节蛋白用于预防、治疗或延迟心肌损伤的方法和组合物 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024219524A Division JP7825894B2 (ja) | 2019-01-07 | 2024-12-16 | ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| JP2022516199A JP2022516199A (ja) | 2022-02-24 |
| JPWO2020143548A5 JPWO2020143548A5 (https=) | 2022-12-19 |
| JP2022516199A5 JP2022516199A5 (https=) | 2022-12-19 |
| JP7630173B2 true JP7630173B2 (ja) | 2025-02-17 |
Family
ID=71485079
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2021539453A Active JP7630173B2 (ja) | 2019-01-07 | 2020-01-03 | ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 |
| JP2024219524A Active JP7825894B2 (ja) | 2019-01-07 | 2024-12-16 | ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2024219524A Active JP7825894B2 (ja) | 2019-01-07 | 2024-12-16 | ニューレグリンを用いて心筋損傷を予防、治療、又は緩和するための方法及びそのための組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20220096599A1 (https=) |
| EP (1) | EP3909599A4 (https=) |
| JP (2) | JP7630173B2 (https=) |
| CN (1) | CN111407881A (https=) |
| AU (1) | AU2020206381B2 (https=) |
| CA (1) | CA3125377A1 (https=) |
| WO (1) | WO2020143548A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN118236430B (zh) * | 2024-04-07 | 2025-08-26 | 中国人民解放军总医院第六医学中心 | 一种修复肿瘤治疗心肌损伤的药物组合物及其制备方法 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013503110A (ja) | 2009-06-09 | 2013-01-31 | ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド | ニューレグリンに基づく心不全の治療方法 |
| JP2016516016A (ja) | 2013-03-06 | 2016-06-02 | アコーダ セラピューティクス インコーポレイテッド | 心不全の治療または予防のためのニューレグリンまたはその断片の治療的投与の方法 |
| JP2018533922A (ja) | 2015-09-25 | 2018-11-22 | ダグラス ビー. ソーヤー, | 心臓傷害を処置するための方法 |
Family Cites Families (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5716930A (en) | 1991-04-10 | 1998-02-10 | Ludwig Institute For Cancer Research | Glial growth factors |
| US5530109A (en) | 1991-04-10 | 1996-06-25 | Ludwig Institute For Cancer Research | DNA encoding glial mitogenic factors |
| US5834229A (en) | 1991-05-24 | 1998-11-10 | Genentech, Inc. | Nucleic acids vectors and host cells encoding and expressing heregulin 2-α |
| US5912326A (en) | 1995-09-08 | 1999-06-15 | President And Fellows Of Harvard College | Cerebellum-derived growth factors |
| US6635249B1 (en) | 1999-04-23 | 2003-10-21 | Cenes Pharmaceuticals, Inc. | Methods for treating congestive heart failure |
| US20010041869A1 (en) | 2000-03-23 | 2001-11-15 | Causey James D. | Control tabs for infusion devices and methods of using the same |
| US6589229B1 (en) | 2000-07-31 | 2003-07-08 | Becton, Dickinson And Company | Wearable, self-contained drug infusion device |
| CN1498656A (zh) * | 2002-11-08 | 2004-05-26 | 上海泽生科技开发有限公司 | 神经调节蛋白用于心肌梗死治疗的方法和组合物 |
| WO2003099320A1 (en) * | 2002-05-24 | 2003-12-04 | Zensun (Shanghai) Sci-Tech.Ltd | Neuregulin based methods and compositions for treating viral myocarditis and dilated cardiomyopathy |
| US7144384B2 (en) | 2002-09-30 | 2006-12-05 | Insulet Corporation | Dispenser components and methods for patient infusion device |
| US7128727B2 (en) | 2002-09-30 | 2006-10-31 | Flaherty J Christopher | Components and methods for patient infusion device |
| US20050065760A1 (en) | 2003-09-23 | 2005-03-24 | Robert Murtfeldt | Method for advising patients concerning doses of insulin |
| US7686787B2 (en) | 2005-05-06 | 2010-03-30 | Medtronic Minimed, Inc. | Infusion device and method with disposable portion |
| JP5738516B2 (ja) * | 2005-12-30 | 2015-06-24 | ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド | 心機能改善のためのニューレグリンの徐放 |
| CN101394861A (zh) * | 2005-12-30 | 2009-03-25 | 上海泽生科技开发有限公司 | 纽兰格林持续给药能改善心脏功能 |
| CN103768582A (zh) * | 2006-12-29 | 2014-05-07 | 上海泽生科技开发有限公司 | 纽兰格林持续给药能改善心脏功能 |
| CN102245189B (zh) * | 2008-12-03 | 2015-06-17 | 阿莫塞特公司 | 改善梗死区灌注的组合物以及血管损伤修复方法 |
| JP6096262B2 (ja) * | 2009-08-25 | 2017-03-15 | ゼンサン (シャンハイ) サイエンス アンド テクノロジー,シーオー.,エルティーディー. | ニューレグリンに基づく心不全の治療方法 |
| CN102139095A (zh) * | 2010-01-29 | 2011-08-03 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟心脏缺血再灌注损伤的方法和组合物 |
| WO2013053076A1 (en) * | 2011-10-10 | 2013-04-18 | Zensun (Shanghai)Science & Technology Limited | Compositions and methods for treating heart failure |
| CN103127579B (zh) | 2011-11-21 | 2017-06-16 | 上海泽生科技开发股份有限公司 | 便携式注射泵的驱动系统 |
| US10894815B2 (en) * | 2012-10-08 | 2021-01-19 | Zensun (Shanghai) Science & Technology, Co., Ltd. | Compositions and methods for treating heart failure in diabetic patients |
| RU2015154737A (ru) * | 2013-05-22 | 2017-06-27 | Цзэньсунь (Шанхай) Сайенс Энд Текнолоджи, Ко., Лтд. | Пролонгированное высвобождение нейрегулина для лечения сердечной недостаточности |
| CN105561298A (zh) * | 2014-10-17 | 2016-05-11 | 上海泽生科技开发有限公司 | 神经调节蛋白用于预防、治疗或延迟射血分数保留的心力衰竭的方法和组合物 |
| WO2018052374A1 (en) * | 2016-09-14 | 2018-03-22 | Agency For Science, Technology And Research | Modulation of tjp1 expression to regulate regeneration of heart cells |
| JP2017125032A (ja) * | 2017-02-20 | 2017-07-20 | ゼンスン(シャンハイ)サイエンス アンド テクノロジー カンパニー リミテッド | 糖尿病患者における心不全の治療用組成物 |
-
2019
- 2019-12-31 CN CN201911412811.1A patent/CN111407881A/zh active Pending
-
2020
- 2020-01-03 US US17/420,974 patent/US20220096599A1/en active Pending
- 2020-01-03 JP JP2021539453A patent/JP7630173B2/ja active Active
- 2020-01-03 WO PCT/CN2020/070299 patent/WO2020143548A1/zh not_active Ceased
- 2020-01-03 CA CA3125377A patent/CA3125377A1/en active Pending
- 2020-01-03 AU AU2020206381A patent/AU2020206381B2/en active Active
- 2020-01-03 EP EP20738153.4A patent/EP3909599A4/en active Pending
-
2024
- 2024-12-16 JP JP2024219524A patent/JP7825894B2/ja active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013503110A (ja) | 2009-06-09 | 2013-01-31 | ゼンサン (シャンハイ) サイエンス アンド テクノロジー リミテッド | ニューレグリンに基づく心不全の治療方法 |
| JP2016516016A (ja) | 2013-03-06 | 2016-06-02 | アコーダ セラピューティクス インコーポレイテッド | 心不全の治療または予防のためのニューレグリンまたはその断片の治療的投与の方法 |
| JP2018533922A (ja) | 2015-09-25 | 2018-11-22 | ダグラス ビー. ソーヤー, | 心臓傷害を処置するための方法 |
Non-Patent Citations (1)
| Title |
|---|
| Zensen Announces Positive Clinical Results for NeucardinTM to Improve Heart Function and Reduce Mortality in Chronic Heart Failure Patients,FIERCE Pharma,2013年,[Retrieved on 2023.11.30], Retrieved from the Internet: <URL: https://www.fiercepharma.com/pharma/zensun-announces-positive-clinical-results-for-neucardinTM-to-improve-heart-function-and> |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3909599A4 (en) | 2022-09-28 |
| EP3909599A1 (en) | 2021-11-17 |
| JP7825894B2 (ja) | 2026-03-09 |
| WO2020143548A1 (zh) | 2020-07-16 |
| CA3125377A1 (en) | 2020-07-16 |
| AU2020206381B2 (en) | 2026-01-22 |
| JP2025060703A (ja) | 2025-04-10 |
| AU2020206381A1 (en) | 2021-07-29 |
| CN111407881A (zh) | 2020-07-14 |
| US20220096599A1 (en) | 2022-03-31 |
| JP2022516199A (ja) | 2022-02-24 |
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