JP7624219B2 - ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法 - Google Patents

ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法 Download PDF

Info

Publication number
JP7624219B2
JP7624219B2 JP2021512838A JP2021512838A JP7624219B2 JP 7624219 B2 JP7624219 B2 JP 7624219B2 JP 2021512838 A JP2021512838 A JP 2021512838A JP 2021512838 A JP2021512838 A JP 2021512838A JP 7624219 B2 JP7624219 B2 JP 7624219B2
Authority
JP
Japan
Prior art keywords
acnes
skin
epidermidis
seq
capitis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2021512838A
Other languages
English (en)
Japanese (ja)
Other versions
JP2022501330A (ja
JP2022501330A5 (https=
JPWO2020056359A5 (https=
Inventor
エル ギャロ、リチャード
ナカツジ、テルアキ
オー オニール、アラン
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of California San Diego UCSD
Original Assignee
University of California San Diego UCSD
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of California San Diego UCSD filed Critical University of California San Diego UCSD
Publication of JP2022501330A publication Critical patent/JP2022501330A/ja
Publication of JP2022501330A5 publication Critical patent/JP2022501330A5/ja
Publication of JPWO2020056359A5 publication Critical patent/JPWO2020056359A5/ja
Priority to JP2024084404A priority Critical patent/JP2024112944A/ja
Application granted granted Critical
Publication of JP7624219B2 publication Critical patent/JP7624219B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911Bacteria
    • G01N33/56938Staphylococcus
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • A61K2035/115Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84Products or compounds obtained by lyophilisation, freeze-drying
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/20Dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Birds (AREA)
JP2021512838A 2018-09-13 2019-09-13 ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法 Active JP7624219B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024084404A JP2024112944A (ja) 2018-09-13 2024-05-23 ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862730999P 2018-09-13 2018-09-13
US62/730,999 2018-09-13
PCT/US2019/051156 WO2020056359A1 (en) 2018-09-13 2019-09-13 Bacteriotherapy against proprionibacterium acnes for the treatment of acne

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024084404A Division JP2024112944A (ja) 2018-09-13 2024-05-23 ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法

Publications (4)

Publication Number Publication Date
JP2022501330A JP2022501330A (ja) 2022-01-06
JP2022501330A5 JP2022501330A5 (https=) 2022-08-29
JPWO2020056359A5 JPWO2020056359A5 (https=) 2022-08-29
JP7624219B2 true JP7624219B2 (ja) 2025-01-30

Family

ID=69777906

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2021512838A Active JP7624219B2 (ja) 2018-09-13 2019-09-13 ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法
JP2024084404A Pending JP2024112944A (ja) 2018-09-13 2024-05-23 ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2024084404A Pending JP2024112944A (ja) 2018-09-13 2024-05-23 ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法

Country Status (10)

Country Link
US (1) US20210283215A1 (https=)
EP (1) EP3849573B1 (https=)
JP (2) JP7624219B2 (https=)
KR (1) KR20210102871A (https=)
CN (1) CN113286602A (https=)
AU (1) AU2019339515B2 (https=)
BR (1) BR112021004538A2 (https=)
CA (1) CA3112041A1 (https=)
MX (1) MX2021003006A (https=)
WO (1) WO2020056359A1 (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020279533A1 (en) * 2019-05-20 2021-12-23 L'ORéAL S.A. Composition for treatment, alleviation or prophylaxis of acne
CN115261495B (zh) * 2021-04-30 2024-11-22 上海旺旺食品集团有限公司 一种检测金黄色葡萄球菌的方法、检测系统及其应用
CZ309480B6 (cs) * 2021-09-30 2023-02-15 BiomServ s.r.o Přípravky na ochranu mikrobiomu kůže a sliznic proti patogenním mikrobům a virům
CN114990237B (zh) * 2021-10-29 2024-11-26 成都中医药大学 一种检测金黄色葡萄球菌的引物、试剂盒和方法
CN115569229B (zh) * 2022-08-30 2023-12-22 中南大学湘雅三医院 搭载多种后生元成分的皮肤软组织保护材料及其制备方法
CN115852004B (zh) * 2023-02-07 2025-12-12 南京大学 一种表皮葡萄球菌的病原体特异性核酸基因及检测方法
CN116270368A (zh) * 2023-05-15 2023-06-23 天津悟空美容科技有限责任公司 一种抗痤疮化妆品及制备方法
CN118755644B (zh) * 2024-09-05 2025-02-11 山东福瑞达生物股份有限公司 一株头状葡萄球菌、一种菌剂及应用和一种头皮护理产品
CN119391608B (zh) * 2025-01-02 2025-10-28 中国疾病预防控制中心传染病预防控制所 表皮葡萄球菌共生菌cgmcc no.31064及应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018515488A (ja) 2015-05-05 2018-06-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗菌療法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10111913B2 (en) * 2011-02-04 2018-10-30 Joseph E. Kovarik Method of reducing the likelihood of skin cancer in an individual human being
JP6620099B2 (ja) 2013-12-23 2019-12-11 ブルーカー ダルトニック ゲーエムベーハー メシチリン耐性黄色ブドウ球菌(mrsa)の同定
WO2015106175A1 (en) * 2014-01-10 2015-07-16 The Regents Of The University Of California Skin probiotic
CN107794232B (zh) * 2016-08-31 2022-03-08 广州金羿噬菌体生物技术有限公司 拮抗痤疮丙酸杆菌和革兰氏阳性菌生长的链球菌及其代谢产物

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018515488A (ja) 2015-05-05 2018-06-14 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 抗菌療法

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Appl. Microbiol. Biotechnol.,2014年,vol.98, issue 1,p.411-424
BMC Genomics,2016年,vol.17,152, p.1-14
J. Invest. Dermatol.,2010年,vol.130, issue 1,p.192-200
Sci. Rep.,2017年,vol.7,10447, p.1-10

Also Published As

Publication number Publication date
JP2022501330A (ja) 2022-01-06
CN113286602A (zh) 2021-08-20
AU2019339515B2 (en) 2026-04-23
WO2020056359A1 (en) 2020-03-19
EP3849573B1 (en) 2025-10-29
KR20210102871A (ko) 2021-08-20
CA3112041A1 (en) 2020-03-19
EP3849573C0 (en) 2025-10-29
AU2019339515A1 (en) 2021-03-25
BR112021004538A2 (pt) 2021-06-08
JP2024112944A (ja) 2024-08-21
EP3849573A1 (en) 2021-07-21
MX2021003006A (es) 2021-05-27
US20210283215A1 (en) 2021-09-16
EP3849573A4 (en) 2022-05-11

Similar Documents

Publication Publication Date Title
JP7624219B2 (ja) ニキビの治療のためのプロピオニバクテリウム・アクネスに対する細菌療法
AU2022203288B2 (en) Antimicrobial therapy
O’Neill et al. Identification of a human skin commensal bacterium that selectively kills Cutibacterium acnes
US20240299468A1 (en) Compositions and methods for treatment of skin disorders
US20240100105A1 (en) Bacteriophage treatment for acne and biofilms
KR101885403B1 (ko) 신규 락트산 박테리아 및 그를 함유하는 조성물
CN119530100A (zh) 一种改善皮肤的多乳杆菌组合物及其衍生物和应用
KR20250061733A (ko) 여드름 치료를 위한 푸소박테리움 뉴클레아툼
WO2026035530A1 (en) Commensal bacteriotherapy of acne
EP4680718A1 (en) Skin archaea preparation
HK40099263A (zh) 用於改善皮肤健康以及用於治疗和预防与真菌及其他病原微生物相关的疾病、病症和病况的组合物和方法
HK40089238A (zh) 抗微生物疗法
CN115715799A (zh) 用于预防或治疗真菌感染的组合物及其制剂、制备方法和应用

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20220819

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20220819

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20230426

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20230502

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20230607

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20231101

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20240125

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20240523

A911 Transfer to examiner for re-examination before appeal (zenchi)

Free format text: JAPANESE INTERMEDIATE CODE: A911

Effective date: 20240612

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20240902

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20241126

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20241224

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20250110

R150 Certificate of patent or registration of utility model

Ref document number: 7624219

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150