CN113286602A - 用于治疗痤疮的针对痤疮丙酸杆菌的细菌疗法 - Google Patents

用于治疗痤疮的针对痤疮丙酸杆菌的细菌疗法 Download PDF

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Publication number
CN113286602A
CN113286602A CN201980071752.8A CN201980071752A CN113286602A CN 113286602 A CN113286602 A CN 113286602A CN 201980071752 A CN201980071752 A CN 201980071752A CN 113286602 A CN113286602 A CN 113286602A
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China
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composition
staphylococcus
psm
staphylococcus epidermidis
propionibacterium acnes
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Pending
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CN201980071752.8A
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English (en)
Chinese (zh)
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R·L·伽罗
仲辻晃明
A·O·奥尼尔
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University of California San Diego UCSD
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University of California San Diego UCSD
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02—Local antiseptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G01N33/56938—Staphylococcus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11—Medicinal preparations comprising living procariotic cells
    • A61K2035/115—Probiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/84—Products or compounds obtained by lyophilisation, freeze-drying
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/85—Products or compounds obtained by fermentation, e.g. yoghurt, beer, wine
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/20—Dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Birds (AREA)
CN201980071752.8A 2018-09-13 2019-09-13 用于治疗痤疮的针对痤疮丙酸杆菌的细菌疗法 Pending CN113286602A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862730999P 2018-09-13 2018-09-13
US62/730999 2018-09-13
PCT/US2019/051156 WO2020056359A1 (en) 2018-09-13 2019-09-13 Bacteriotherapy against proprionibacterium acnes for the treatment of acne

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CN113286602A true CN113286602A (zh) 2021-08-20

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US (1) US20210283215A1 (https=)
EP (1) EP3849573B1 (https=)
JP (2) JP7624219B2 (https=)
KR (1) KR20210102871A (https=)
CN (1) CN113286602A (https=)
AU (1) AU2019339515B2 (https=)
BR (1) BR112021004538A2 (https=)
CA (1) CA3112041A1 (https=)
MX (1) MX2021003006A (https=)
WO (1) WO2020056359A1 (https=)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114990237A (zh) * 2021-10-29 2022-09-02 成都中医药大学 一种检测金黄色葡萄球菌的引物、试剂盒和方法
CN115261495A (zh) * 2021-04-30 2022-11-01 上海旺旺食品集团有限公司 一种检测金黄色葡萄球菌的方法、检测系统及其应用
CN115569229A (zh) * 2022-08-30 2023-01-06 中南大学湘雅三医院 搭载多种后生元成分的皮肤软组织保护材料及其制备方法
CN115852004A (zh) * 2023-02-07 2023-03-28 南京大学 一种表皮葡萄球菌的病原体特异性核酸基因及检测方法
CN116270368A (zh) * 2023-05-15 2023-06-23 天津悟空美容科技有限责任公司 一种抗痤疮化妆品及制备方法
CN118755644A (zh) * 2024-09-05 2024-10-11 山东福瑞达生物股份有限公司 一株头状葡萄球菌、一种菌剂及应用和一种头皮护理产品
CN119391608A (zh) * 2025-01-02 2025-02-07 中国疾病预防控制中心传染病预防控制所 表皮葡萄球菌共生菌cgmcc no.31064及应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2020279533A1 (en) * 2019-05-20 2021-12-23 L'ORéAL S.A. Composition for treatment, alleviation or prophylaxis of acne
CZ309480B6 (cs) * 2021-09-30 2023-02-15 BiomServ s.r.o Přípravky na ochranu mikrobiomu kůže a sliznic proti patogenním mikrobům a virům

Citations (3)

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US20170119827A1 (en) * 2011-02-04 2017-05-04 Joseph E. Kovarik Method and System to Improve the Health of a Person's Skin Microbiome
CN107735098A (zh) * 2015-05-05 2018-02-23 加利福尼亚大学董事会 抗微生物疗法
CN107794232A (zh) * 2016-08-31 2018-03-13 广州金羿噬菌体生物技术有限公司 拮抗痤疮丙酸杆菌和革兰氏阳性菌生长的链球菌及其代谢产物

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JP6620099B2 (ja) 2013-12-23 2019-12-11 ブルーカー ダルトニック ゲーエムベーハー メシチリン耐性黄色ブドウ球菌（ｍｒｓａ）の同定
WO2015106175A1 (en) * 2014-01-10 2015-07-16 The Regents Of The University Of California Skin probiotic

Patent Citations (3)

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US20170119827A1 (en) * 2011-02-04 2017-05-04 Joseph E. Kovarik Method and System to Improve the Health of a Person's Skin Microbiome
CN107735098A (zh) * 2015-05-05 2018-02-23 加利福尼亚大学董事会 抗微生物疗法
CN107794232A (zh) * 2016-08-31 2018-03-13 广州金羿噬菌体生物技术有限公司 拮抗痤疮丙酸杆菌和革兰氏阳性菌生长的链球菌及其代谢产物

Non-Patent Citations (1)

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Title
庞晓文等: "聚合性痤疮病原菌耐药性及对米诺环素疗效的分析", 临床皮肤科杂志, vol. 33, no. 07, pages 444 *

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115261495A (zh) * 2021-04-30 2022-11-01 上海旺旺食品集团有限公司 一种检测金黄色葡萄球菌的方法、检测系统及其应用
CN115261495B (zh) * 2021-04-30 2024-11-22 上海旺旺食品集团有限公司 一种检测金黄色葡萄球菌的方法、检测系统及其应用
CN114990237A (zh) * 2021-10-29 2022-09-02 成都中医药大学 一种检测金黄色葡萄球菌的引物、试剂盒和方法
CN115569229A (zh) * 2022-08-30 2023-01-06 中南大学湘雅三医院 搭载多种后生元成分的皮肤软组织保护材料及其制备方法
CN115569229B (zh) * 2022-08-30 2023-12-22 中南大学湘雅三医院 搭载多种后生元成分的皮肤软组织保护材料及其制备方法
CN115852004A (zh) * 2023-02-07 2023-03-28 南京大学 一种表皮葡萄球菌的病原体特异性核酸基因及检测方法
CN116270368A (zh) * 2023-05-15 2023-06-23 天津悟空美容科技有限责任公司 一种抗痤疮化妆品及制备方法
CN118755644A (zh) * 2024-09-05 2024-10-11 山东福瑞达生物股份有限公司 一株头状葡萄球菌、一种菌剂及应用和一种头皮护理产品
CN119391608A (zh) * 2025-01-02 2025-02-07 中国疾病预防控制中心传染病预防控制所 表皮葡萄球菌共生菌cgmcc no.31064及应用

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JP2022501330A (ja) 2022-01-06
JP7624219B2 (ja) 2025-01-30
AU2019339515B2 (en) 2026-04-23
WO2020056359A1 (en) 2020-03-19
EP3849573B1 (en) 2025-10-29
KR20210102871A (ko) 2021-08-20
CA3112041A1 (en) 2020-03-19
EP3849573C0 (en) 2025-10-29
AU2019339515A1 (en) 2021-03-25
BR112021004538A2 (pt) 2021-06-08
JP2024112944A (ja) 2024-08-21
EP3849573A1 (en) 2021-07-21
MX2021003006A (es) 2021-05-27
US20210283215A1 (en) 2021-09-16
EP3849573A4 (en) 2022-05-11

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