JP7598766B2 - 薬物送達デバイスのための作動機構 - Google Patents

薬物送達デバイスのための作動機構 Download PDF

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Publication number
JP7598766B2
JP7598766B2 JP2020573011A JP2020573011A JP7598766B2 JP 7598766 B2 JP7598766 B2 JP 7598766B2 JP 2020573011 A JP2020573011 A JP 2020573011A JP 2020573011 A JP2020573011 A JP 2020573011A JP 7598766 B2 JP7598766 B2 JP 7598766B2
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Japan
Prior art keywords
shield
engagement region
nut
trigger ring
plunger rod
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JP2020573011A
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English (en)
Japanese (ja)
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JP2021533844A5 (enExample
JP2021533844A (ja
Inventor
メランダー，マティアス
ダドマン，ジョシュア
イグレシアス，ジョーセフ・マイケル
ルズビ・スベンセン，ビャルケ・リッケ
マッカロー，アダム・ビー
プラムベック，クリスティアン
サンチェス，スティーブ
Original Assignee
アムジエン・インコーポレーテツド
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Publication of JP2021533844A publication Critical patent/JP2021533844A/ja
Publication of JP2021533844A5 publication Critical patent/JP2021533844A5/ja
Priority to JP2024208101A priority Critical patent/JP7766775B2/ja
Application granted granted Critical
Publication of JP7598766B2 publication Critical patent/JP7598766B2/ja
Priority to JP2025180209A priority patent/JP2026021404A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31571—Means preventing accidental administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
    • A61M5/31585—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
JP2020573011A 2018-08-17 2019-08-16 薬物送達デバイスのための作動機構 Active JP7598766B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2024208101A JP7766775B2 (ja) 2018-08-17 2024-11-29 薬物送達デバイスのための作動機構
JP2025180209A JP2026021404A (ja) 2018-08-17 2025-10-27 薬物送達デバイスのための作動機構

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862719367P 2018-08-17 2018-08-17
US62/719,367 2018-08-17
PCT/US2019/046899 WO2020037256A1 (en) 2018-08-17 2019-08-16 Activation mechanism for drug delivery device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2024208101A Division JP7766775B2 (ja) 2018-08-17 2024-11-29 薬物送達デバイスのための作動機構

Publications (3)

Publication Number Publication Date
JP2021533844A JP2021533844A (ja) 2021-12-09
JP2021533844A5 JP2021533844A5 (enExample) 2022-08-19
JP7598766B2 true JP7598766B2 (ja) 2024-12-12

Family

ID=67841181

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2020573011A Active JP7598766B2 (ja) 2018-08-17 2019-08-16 薬物送達デバイスのための作動機構
JP2024208101A Active JP7766775B2 (ja) 2018-08-17 2024-11-29 薬物送達デバイスのための作動機構
JP2025180209A Pending JP2026021404A (ja) 2018-08-17 2025-10-27 薬物送達デバイスのための作動機構

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2024208101A Active JP7766775B2 (ja) 2018-08-17 2024-11-29 薬物送達デバイスのための作動機構
JP2025180209A Pending JP2026021404A (ja) 2018-08-17 2025-10-27 薬物送達デバイスのための作動機構

Country Status (11)

Country Link
US (2) US12702762B2 (enExample)
EP (1) EP3836988A1 (enExample)
JP (3) JP7598766B2 (enExample)
CN (2) CN112469455B (enExample)
AU (2) AU2019321678B2 (enExample)
CA (1) CA3105826A1 (enExample)
IL (2) IL316307A (enExample)
MA (1) MA53227A (enExample)
MX (2) MX2021001794A (enExample)
SG (1) SG11202013189WA (enExample)
WO (1) WO2020037256A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7719714B2 (ja) 2018-10-15 2025-08-06 アムジエン・インコーポレーテツド ダンピング機構を有する薬物送達装置
CN115461101A (zh) * 2020-04-24 2022-12-09 费森尤斯卡比德国有限公司 注射器和注射器主体
MX2022014182A (es) * 2020-05-15 2022-12-07 Biocon Biologics Ltd Ensamble de auto-inyector.
CN116171174B (zh) 2020-10-14 2026-01-06 艾斯曲尔医疗公司 用于药剂输送装置的锁定机构
AU2022234298A1 (en) 2021-03-10 2023-08-31 Amgen Inc. Drug delivery device, subassembly for drug delivery device, syringe holder, and method of assembly
CN118019555A (zh) * 2021-10-06 2024-05-10 美国安进公司 用于药物递送装置的撞击激活式固位特征

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007500530A (ja) 2003-07-31 2007-01-18 エス・アイ・ディ・テクノロジーズ・リミテッド・ライアビリティ・カンパニー 注射装置
JP2017519581A (ja) 2014-06-27 2017-07-20 ノボ・ノルデイスク・エー／エス 針シールドトリガー部を有する自動注射器
US20180140783A1 (en) 2016-11-22 2018-05-24 E3D Agricultural Cooperative Association Ltd Actuated needle shielding and shething device

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451210A (en) * 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
KR100911951B1 (ko) 2001-08-23 2009-08-13 젠맵 에이/에스 인터루킨 15 (ｉｌ-15)에 대하여 특이적인 인간 항체
WO2008113864A1 (de) * 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injektionsvorrichtung mit auslösesicherungen
EP2129416A1 (de) * 2007-03-22 2009-12-09 Tecpharma Licensing AG Federanordnung in einer injektionsvorrichtung
EP2438941A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
GB201020475D0 (en) * 2010-12-02 2011-01-19 Oval Medical Technologies Ltd Delivery mechanism for an autoinjector
EP2606925A1 (en) * 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector
EP4327849A3 (en) 2012-03-06 2024-04-24 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
EP3057634A1 (en) * 2013-10-16 2016-08-24 Novo Nordisk A/S Drug delivery device with improved dose reset mechanism
US10406291B2 (en) * 2014-04-04 2019-09-10 Novo Nordisk A/S Autoinjector having needle shield triggering
JP6824262B2 (ja) * 2015-10-30 2021-02-03 ノボ・ノルデイスク・エー／エス 充填済み薬剤送達装置の製造方法
CA3204309C (en) * 2018-07-24 2026-04-28 Antares Pharma, Inc. Formulations for naloxone hyrdochloride injection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007500530A (ja) 2003-07-31 2007-01-18 エス・アイ・ディ・テクノロジーズ・リミテッド・ライアビリティ・カンパニー 注射装置
JP2017519581A (ja) 2014-06-27 2017-07-20 ノボ・ノルデイスク・エー／エス 針シールドトリガー部を有する自動注射器
US20180140783A1 (en) 2016-11-22 2018-05-24 E3D Agricultural Cooperative Association Ltd Actuated needle shielding and shething device

Also Published As

Publication number Publication date
IL279811A (en) 2021-03-01
AU2019321678B2 (en) 2024-11-07
JP2026021404A (ja) 2026-02-10
AU2025200635A1 (en) 2025-02-20
IL279811B2 (en) 2025-03-01
SG11202013189WA (en) 2021-01-28
MA53227A (fr) 2021-11-24
US20250152838A1 (en) 2025-05-15
CN112469455B (zh) 2024-03-22
CN118217484A (zh) 2024-06-21
IL316307A (en) 2024-12-01
CA3105826A1 (en) 2020-02-20
MX2024013000A (es) 2024-11-08
WO2020037256A1 (en) 2020-02-20
JP7766775B2 (ja) 2025-11-10
US20210260302A1 (en) 2021-08-26
US12702762B2 (en) 2026-08-11
CN112469455A (zh) 2021-03-09
JP2025027087A (ja) 2025-02-26
AU2019321678A1 (en) 2021-01-28
MX2021001794A (es) 2021-04-19
EP3836988A1 (en) 2021-06-23
IL279811B1 (en) 2024-11-01
JP2021533844A (ja) 2021-12-09

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