CN112469455B - 用于药物递送装置的启动机构 - Google Patents

用于药物递送装置的启动机构 Download PDF

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Publication number
CN112469455B
CN112469455B CN201980048699.XA CN201980048699A CN112469455B CN 112469455 B CN112469455 B CN 112469455B CN 201980048699 A CN201980048699 A CN 201980048699A CN 112469455 B CN112469455 B CN 112469455B
Authority
CN
China
Prior art keywords
housing
drug delivery
shield
delivery device
engagement region
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201980048699.XA
Other languages
English (en)
Chinese (zh)
Other versions
CN112469455A (zh
Inventor
M·梅兰德
J·达德曼
J·M·伊格莱西亚斯
B·L·卢德维格斯文森
A·B·麦卡洛
C·普兰贝克
S·桑切斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Priority to CN202410343562.XA priority Critical patent/CN118217484A/zh
Publication of CN112469455A publication Critical patent/CN112469455A/zh
Application granted granted Critical
Publication of CN112469455B publication Critical patent/CN112469455B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31571—Means preventing accidental administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
    • A61M5/31585—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
CN201980048699.XA 2018-08-17 2019-08-16 用于药物递送装置的启动机构 Active CN112469455B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202410343562.XA CN118217484A (zh) 2018-08-17 2019-08-16 用于药物递送装置的启动机构

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862719367P 2018-08-17 2018-08-17
US62/719,367 2018-08-17
PCT/US2019/046899 WO2020037256A1 (en) 2018-08-17 2019-08-16 Activation mechanism for drug delivery device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN202410343562.XA Division CN118217484A (zh) 2018-08-17 2019-08-16 用于药物递送装置的启动机构

Publications (2)

Publication Number Publication Date
CN112469455A CN112469455A (zh) 2021-03-09
CN112469455B true CN112469455B (zh) 2024-03-22

Family

ID=67841181

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201980048699.XA Active CN112469455B (zh) 2018-08-17 2019-08-16 用于药物递送装置的启动机构
CN202410343562.XA Pending CN118217484A (zh) 2018-08-17 2019-08-16 用于药物递送装置的启动机构

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN202410343562.XA Pending CN118217484A (zh) 2018-08-17 2019-08-16 用于药物递送装置的启动机构

Country Status (11)

Country Link
US (2) US12702762B2 (enExample)
EP (1) EP3836988A1 (enExample)
JP (3) JP7598766B2 (enExample)
CN (2) CN112469455B (enExample)
AU (2) AU2019321678B2 (enExample)
CA (1) CA3105826A1 (enExample)
IL (2) IL316307A (enExample)
MA (1) MA53227A (enExample)
MX (2) MX2021001794A (enExample)
SG (1) SG11202013189WA (enExample)
WO (1) WO2020037256A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7719714B2 (ja) 2018-10-15 2025-08-06 アムジエン・インコーポレーテツド ダンピング機構を有する薬物送達装置
CN115461101A (zh) * 2020-04-24 2022-12-09 费森尤斯卡比德国有限公司 注射器和注射器主体
MX2022014182A (es) * 2020-05-15 2022-12-07 Biocon Biologics Ltd Ensamble de auto-inyector.
CN116171174B (zh) 2020-10-14 2026-01-06 艾斯曲尔医疗公司 用于药剂输送装置的锁定机构
AU2022234298A1 (en) 2021-03-10 2023-08-31 Amgen Inc. Drug delivery device, subassembly for drug delivery device, syringe holder, and method of assembly
CN118019555A (zh) * 2021-10-06 2024-05-10 美国安进公司 用于药物递送装置的撞击激活式固位特征

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008113864A1 (de) * 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injektionsvorrichtung mit auslösesicherungen
EP2438941A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
EP2606925A1 (en) * 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector
CN106456907A (zh) * 2014-06-27 2017-02-22 诺和诺德股份有限公司 具有针罩触发的自动注射器

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US5451210A (en) * 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
KR100911951B1 (ko) 2001-08-23 2009-08-13 젠맵 에이/에스 인터루킨 15 (ｉｌ-15)에 대하여 특이적인 인간 항체
US20050027255A1 (en) 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
EP2129416A1 (de) * 2007-03-22 2009-12-09 Tecpharma Licensing AG Federanordnung in einer injektionsvorrichtung
GB201020475D0 (en) * 2010-12-02 2011-01-19 Oval Medical Technologies Ltd Delivery mechanism for an autoinjector
EP4327849A3 (en) 2012-03-06 2024-04-24 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
EP3057634A1 (en) * 2013-10-16 2016-08-24 Novo Nordisk A/S Drug delivery device with improved dose reset mechanism
US10406291B2 (en) * 2014-04-04 2019-09-10 Novo Nordisk A/S Autoinjector having needle shield triggering
JP6824262B2 (ja) * 2015-10-30 2021-02-03 ノボ・ノルデイスク・エー／エス 充填済み薬剤送達装置の製造方法
US20180140783A1 (en) * 2016-11-22 2018-05-24 E3D Agricultural Cooperative Association Ltd Actuated needle shielding and shething device
CA3204309C (en) * 2018-07-24 2026-04-28 Antares Pharma, Inc. Formulations for naloxone hyrdochloride injection

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008113864A1 (de) * 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injektionsvorrichtung mit auslösesicherungen
EP2438941A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
EP2606925A1 (en) * 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector
CN106456907A (zh) * 2014-06-27 2017-02-22 诺和诺德股份有限公司 具有针罩触发的自动注射器

Also Published As

Publication number Publication date
IL279811A (en) 2021-03-01
AU2019321678B2 (en) 2024-11-07
JP2026021404A (ja) 2026-02-10
AU2025200635A1 (en) 2025-02-20
IL279811B2 (en) 2025-03-01
SG11202013189WA (en) 2021-01-28
MA53227A (fr) 2021-11-24
JP7598766B2 (ja) 2024-12-12
US20250152838A1 (en) 2025-05-15
CN118217484A (zh) 2024-06-21
IL316307A (en) 2024-12-01
CA3105826A1 (en) 2020-02-20
MX2024013000A (es) 2024-11-08
WO2020037256A1 (en) 2020-02-20
JP7766775B2 (ja) 2025-11-10
US20210260302A1 (en) 2021-08-26
US12702762B2 (en) 2026-08-11
CN112469455A (zh) 2021-03-09
JP2025027087A (ja) 2025-02-26
AU2019321678A1 (en) 2021-01-28
MX2021001794A (es) 2021-04-19
EP3836988A1 (en) 2021-06-23
IL279811B1 (en) 2024-11-01
JP2021533844A (ja) 2021-12-09

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