AU2019321678B2 - Activation mechanism for drug delivery device - Google Patents

Activation mechanism for drug delivery device Download PDF

Info

Publication number
AU2019321678B2
AU2019321678B2 AU2019321678A AU2019321678A AU2019321678B2 AU 2019321678 B2 AU2019321678 B2 AU 2019321678B2 AU 2019321678 A AU2019321678 A AU 2019321678A AU 2019321678 A AU2019321678 A AU 2019321678A AU 2019321678 B2 AU2019321678 B2 AU 2019321678B2
Authority
AU
Australia
Prior art keywords
shield
trigger ring
engagement region
plunger rod
nut
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2019321678A
Other languages
English (en)
Other versions
AU2019321678A1 (en
Inventor
Joshua DUDMAN
Joseph Michael Iglesias
Bjarke Lykke Ludvig Svendsen
Adam B. Mccullough
Matias Melander
Christian Plambech
Steve Sanchez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amgen Inc
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of AU2019321678A1 publication Critical patent/AU2019321678A1/en
Application granted granted Critical
Publication of AU2019321678B2 publication Critical patent/AU2019321678B2/en
Priority to AU2025200635A priority Critical patent/AU2025200635A1/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2033—Spring-loaded one-shot injectors with or without automatic needle insertion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/3157—Means providing feedback signals when administration is completed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31566—Means improving security or handling thereof
    • A61M5/31571—Means preventing accidental administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features; Drive mechanisms or modes for piston rods
    • A61M5/31583—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it
    • A61M5/31585—Constructional features; Drive mechanisms or modes for piston rods the piston rod being moved by the rotational movement of a component directly in contact with it the component being manually operated or triggered by an axially moving actuator operated by user, e.g. an axially movable injection button
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/3159—Dose expelling manners
    • A61M5/31591—Single dose, i.e. individually set dose administered only once from the same medicament reservoir, e.g. including single stroke limiting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3202—Devices for protection of the needle before use, e.g. caps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/321—Means for protection against accidental injuries by used needles
    • A61M5/3243—Means for protection against accidental injuries by used needles being axially-extensible, e.g. protective sleeves coaxially slidable on the syringe barrel
    • A61M5/326—Fully automatic sleeve extension, i.e. in which triggering of the sleeve does not require a deliberate action by the user
    • A61M2005/3267—Biased sleeves where the needle is uncovered by insertion of the needle into a patient's body

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
AU2019321678A 2018-08-17 2019-08-16 Activation mechanism for drug delivery device Active AU2019321678B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2025200635A AU2025200635A1 (en) 2018-08-17 2025-01-30 Activation mechanism for drug delivery device

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862719367P 2018-08-17 2018-08-17
US62/719,367 2018-08-17
PCT/US2019/046899 WO2020037256A1 (en) 2018-08-17 2019-08-16 Activation mechanism for drug delivery device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2025200635A Division AU2025200635A1 (en) 2018-08-17 2025-01-30 Activation mechanism for drug delivery device

Publications (2)

Publication Number Publication Date
AU2019321678A1 AU2019321678A1 (en) 2021-01-28
AU2019321678B2 true AU2019321678B2 (en) 2024-11-07

Family

ID=67841181

Family Applications (2)

Application Number Title Priority Date Filing Date
AU2019321678A Active AU2019321678B2 (en) 2018-08-17 2019-08-16 Activation mechanism for drug delivery device
AU2025200635A Pending AU2025200635A1 (en) 2018-08-17 2025-01-30 Activation mechanism for drug delivery device

Family Applications After (1)

Application Number Title Priority Date Filing Date
AU2025200635A Pending AU2025200635A1 (en) 2018-08-17 2025-01-30 Activation mechanism for drug delivery device

Country Status (11)

Country Link
US (2) US12702762B2 (enExample)
EP (1) EP3836988A1 (enExample)
JP (3) JP7598766B2 (enExample)
CN (2) CN112469455B (enExample)
AU (2) AU2019321678B2 (enExample)
CA (1) CA3105826A1 (enExample)
IL (2) IL316307A (enExample)
MA (1) MA53227A (enExample)
MX (2) MX2021001794A (enExample)
SG (1) SG11202013189WA (enExample)
WO (1) WO2020037256A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7719714B2 (ja) 2018-10-15 2025-08-06 アムジエン・インコーポレーテツド ダンピング機構を有する薬物送達装置
CN115461101A (zh) * 2020-04-24 2022-12-09 费森尤斯卡比德国有限公司 注射器和注射器主体
MX2022014182A (es) * 2020-05-15 2022-12-07 Biocon Biologics Ltd Ensamble de auto-inyector.
CN116171174B (zh) 2020-10-14 2026-01-06 艾斯曲尔医疗公司 用于药剂输送装置的锁定机构
AU2022234298A1 (en) 2021-03-10 2023-08-31 Amgen Inc. Drug delivery device, subassembly for drug delivery device, syringe holder, and method of assembly
CN118019555A (zh) * 2021-10-06 2024-05-10 美国安进公司 用于药物递送装置的撞击激活式固位特征

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130237921A1 (en) * 2012-03-06 2013-09-12 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US20160228651A1 (en) * 2013-10-16 2016-08-11 Novo Nordisk A/S Drug Delivery Device with Improved Dose Reset Mechanism
US20170143902A1 (en) * 2014-06-27 2017-05-25 Novo Nordisk A/S Autoinjector having needle shield triggering

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5451210A (en) * 1991-04-29 1995-09-19 Lifequest Medical, Inc. System and method for rapid vascular drug delivery
KR100911951B1 (ko) 2001-08-23 2009-08-13 젠맵 에이/에스 인터루킨 15 (ｉｌ-15)에 대하여 특이적인 인간 항체
US20050027255A1 (en) 2003-07-31 2005-02-03 Sid Technologies, Llc Automatic injector
WO2008113864A1 (de) * 2007-03-22 2008-09-25 Tecpharma Licensing Ag Injektionsvorrichtung mit auslösesicherungen
EP2129416A1 (de) * 2007-03-22 2009-12-09 Tecpharma Licensing AG Federanordnung in einer injektionsvorrichtung
EP2438941A1 (en) * 2010-10-08 2012-04-11 Sanofi-Aventis Deutschland GmbH Auto injector with a torsion spring
GB201020475D0 (en) * 2010-12-02 2011-01-19 Oval Medical Technologies Ltd Delivery mechanism for an autoinjector
EP2606925A1 (en) * 2011-12-21 2013-06-26 Sanofi-Aventis Deutschland GmbH Autoinjector
US10406291B2 (en) * 2014-04-04 2019-09-10 Novo Nordisk A/S Autoinjector having needle shield triggering
JP6824262B2 (ja) * 2015-10-30 2021-02-03 ノボ・ノルデイスク・エー／エス 充填済み薬剤送達装置の製造方法
US20180140783A1 (en) * 2016-11-22 2018-05-24 E3D Agricultural Cooperative Association Ltd Actuated needle shielding and shething device
CA3204309C (en) * 2018-07-24 2026-04-28 Antares Pharma, Inc. Formulations for naloxone hyrdochloride injection

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20130237921A1 (en) * 2012-03-06 2013-09-12 Antares Pharma, Inc. Prefilled syringe with breakaway force feature
US20160228651A1 (en) * 2013-10-16 2016-08-11 Novo Nordisk A/S Drug Delivery Device with Improved Dose Reset Mechanism
US20170143902A1 (en) * 2014-06-27 2017-05-25 Novo Nordisk A/S Autoinjector having needle shield triggering

Also Published As

Publication number Publication date
IL279811A (en) 2021-03-01
JP2026021404A (ja) 2026-02-10
AU2025200635A1 (en) 2025-02-20
IL279811B2 (en) 2025-03-01
SG11202013189WA (en) 2021-01-28
MA53227A (fr) 2021-11-24
JP7598766B2 (ja) 2024-12-12
US20250152838A1 (en) 2025-05-15
CN112469455B (zh) 2024-03-22
CN118217484A (zh) 2024-06-21
IL316307A (en) 2024-12-01
CA3105826A1 (en) 2020-02-20
MX2024013000A (es) 2024-11-08
WO2020037256A1 (en) 2020-02-20
JP7766775B2 (ja) 2025-11-10
US20210260302A1 (en) 2021-08-26
US12702762B2 (en) 2026-08-11
CN112469455A (zh) 2021-03-09
JP2025027087A (ja) 2025-02-26
AU2019321678A1 (en) 2021-01-28
MX2021001794A (es) 2021-04-19
EP3836988A1 (en) 2021-06-23
IL279811B1 (en) 2024-11-01
JP2021533844A (ja) 2021-12-09

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FGA Letters patent sealed or granted (standard patent)