JP7551621B2 - 低モル質量金属塩を含む液体ニコチン製剤 - Google Patents

低モル質量金属塩を含む液体ニコチン製剤 Download PDF

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Publication number
JP7551621B2
JP7551621B2 JP2021537916A JP2021537916A JP7551621B2 JP 7551621 B2 JP7551621 B2 JP 7551621B2 JP 2021537916 A JP2021537916 A JP 2021537916A JP 2021537916 A JP2021537916 A JP 2021537916A JP 7551621 B2 JP7551621 B2 JP 7551621B2
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nicotine formulation
liquid nicotine
weight percent
content
water
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Japanese (ja)
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JP2022516859A5 (https=
JP2022516859A (ja
JPWO2020136063A5 (https=
Inventor
イレーヌ タウリーノ
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フィリップ・モーリス・プロダクツ・ソシエテ・アノニム
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    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
JP2021537916A 2018-12-28 2019-12-18 低モル質量金属塩を含む液体ニコチン製剤 Active JP7551621B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18248177 2018-12-28
EP18248177.0 2018-12-28
PCT/EP2019/086111 WO2020136063A1 (en) 2018-12-28 2019-12-18 Liquid nicotine formulation comprising low molar mass metal salt

Publications (4)

Publication Number Publication Date
JP2022516859A JP2022516859A (ja) 2022-03-03
JP2022516859A5 JP2022516859A5 (https=) 2022-12-20
JPWO2020136063A5 JPWO2020136063A5 (https=) 2022-12-20
JP7551621B2 true JP7551621B2 (ja) 2024-09-17

Family

ID=65010470

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2021537916A Active JP7551621B2 (ja) 2018-12-28 2019-12-18 低モル質量金属塩を含む液体ニコチン製剤

Country Status (7)

Country Link
US (1) US12290093B2 (https=)
EP (1) EP3902565B1 (https=)
JP (1) JP7551621B2 (https=)
KR (1) KR102877961B1 (https=)
CN (1) CN113164610A (https=)
BR (1) BR112021010229A2 (https=)
WO (1) WO2020136063A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115191639A (zh) * 2021-04-12 2022-10-18 深圳市合元科技有限公司 气溶胶形成基质以及气溶胶生成系统
CN117378803A (zh) * 2023-10-17 2024-01-12 东莞市吉纯生物技术有限公司 一种固体雾化油及其制备方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011509090A (ja) 2008-01-10 2011-03-24 ブリティッシュ アメリカン タバコ （インヴェストメンツ） リミテッド 経口使用タバコ製品
JP2015531793A (ja) 2012-09-21 2015-11-05 リーガス，バジル ニコチン含有材料および抗がん剤を含む製品
US20180199617A1 (en) 2017-01-18 2018-07-19 Bianca Iodice Tobacco Free Hookah Smoking Gel
WO2018215481A1 (en) 2017-05-24 2018-11-29 Philip Morris Products S.A. Heated aerosol-generating article comprising homogenised botanical material

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008069972A2 (en) 2006-12-01 2008-06-12 Aradigm Corporation Systems for effecting cessation of tobacco use
PL2713778T5 (pl) 2011-05-31 2023-01-30 Philip Morris Products S.A. Pałeczki do zastosowania w wyrobach do palenia
US20170079322A1 (en) 2015-09-18 2017-03-23 Altria Client Services Llc Liquid formulation of an electronic vapor device
GB201516729D0 (en) * 2015-09-22 2015-11-04 The Technology Partnership Plc Liquid nicotine formulation
KR101769817B1 (ko) 2015-10-30 2017-08-30 엘지전자 주식회사 가습청정장치
DK3379952T3 (da) 2015-11-25 2024-01-08 Reynolds Tobacco Co R Nikotinsalte, co-krystaller og salt-co-krystalkomplekser
CN108697152B (zh) * 2015-12-30 2022-01-11 下一代实验室有限责任公司 包含合成尼古丁的尼古丁替代疗法产品
EP3399876B2 (en) 2016-01-07 2026-03-04 Philip Morris Products S.A. Aerosol-generating device with sealed compartment
KR20170118553A (ko) 2016-04-16 2017-10-25 김소진 배터리 호환이 가능한 휴대용 충전기
US12201767B2 (en) 2016-04-22 2025-01-21 Juul Labs, Inc. Aerosol devices having compartmentalized materials
US20180199618A1 (en) 2016-09-27 2018-07-19 Bond Street Manufacturing Llc Vaporizable Tobacco Wax Compositions and Container thereof
BR112021010222A2 (pt) 2018-12-31 2021-08-24 Philip Morris Products S.A. Formulação de nicotina líquida compreendendo solventes imiscíveis em água

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011509090A (ja) 2008-01-10 2011-03-24 ブリティッシュ アメリカン タバコ （インヴェストメンツ） リミテッド 経口使用タバコ製品
JP2015531793A (ja) 2012-09-21 2015-11-05 リーガス，バジル ニコチン含有材料および抗がん剤を含む製品
US20180199617A1 (en) 2017-01-18 2018-07-19 Bianca Iodice Tobacco Free Hookah Smoking Gel
WO2018215481A1 (en) 2017-05-24 2018-11-29 Philip Morris Products S.A. Heated aerosol-generating article comprising homogenised botanical material

Also Published As

Publication number Publication date
JP2022516859A (ja) 2022-03-03
WO2020136063A1 (en) 2020-07-02
KR20210108388A (ko) 2021-09-02
KR102877961B1 (ko) 2025-10-30
BR112021010229A2 (pt) 2021-08-24
EP3902565B1 (en) 2023-04-26
US20220053816A1 (en) 2022-02-24
EP3902565A1 (en) 2021-11-03
US12290093B2 (en) 2025-05-06
CN113164610A (zh) 2021-07-23

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