KR102877961B1 - 저 몰 질량 금속염을 포함하는 액체 니코틴 제형 - Google Patents

저 몰 질량 금속염을 포함하는 액체 니코틴 제형

Info

Publication number
KR102877961B1
KR102877961B1 KR1020217020017A KR20217020017A KR102877961B1 KR 102877961 B1 KR102877961 B1 KR 102877961B1 KR 1020217020017 A KR1020217020017 A KR 1020217020017A KR 20217020017 A KR20217020017 A KR 20217020017A KR 102877961 B1 KR102877961 B1 KR 102877961B1
Authority
KR
South Korea
Prior art keywords
nicotine formulation
liquid nicotine
aerosol
content
weight
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
KR1020217020017A
Other languages
English (en)
Korean (ko)
Other versions
KR20210108388A (ko
Inventor
아이린 타우리노
Original Assignee
필립모리스 프로덕츠 에스.에이.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 필립모리스 프로덕츠 에스.에이. filed Critical 필립모리스 프로덕츠 에스.에이.
Publication of KR20210108388A publication Critical patent/KR20210108388A/ko
Application granted granted Critical
Publication of KR102877961B1 publication Critical patent/KR102877961B1/ko
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
KR1020217020017A 2018-12-28 2019-12-18 저 몰 질량 금속염을 포함하는 액체 니코틴 제형 Active KR102877961B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18248177 2018-12-28
EP18248177.0 2018-12-28
PCT/EP2019/086111 WO2020136063A1 (en) 2018-12-28 2019-12-18 Liquid nicotine formulation comprising low molar mass metal salt

Publications (2)

Publication Number Publication Date
KR20210108388A KR20210108388A (ko) 2021-09-02
KR102877961B1 true KR102877961B1 (ko) 2025-10-30

Family

ID=65010470

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020217020017A Active KR102877961B1 (ko) 2018-12-28 2019-12-18 저 몰 질량 금속염을 포함하는 액체 니코틴 제형

Country Status (7)

Country Link
US (1) US12290093B2 (https=)
EP (1) EP3902565B1 (https=)
JP (1) JP7551621B2 (https=)
KR (1) KR102877961B1 (https=)
CN (1) CN113164610A (https=)
BR (1) BR112021010229A2 (https=)
WO (1) WO2020136063A1 (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115191639A (zh) * 2021-04-12 2022-10-18 深圳市合元科技有限公司 气溶胶形成基质以及气溶胶生成系统
CN117378803A (zh) * 2023-10-17 2024-01-12 东莞市吉纯生物技术有限公司 一种固体雾化油及其制备方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017046400A1 (en) 2015-09-18 2017-03-23 Philip Morris Products S.A. Liquid formulation of an electronic vapor device
WO2017118553A1 (en) 2016-01-07 2017-07-13 Philip Morris Products S.A. Aerosol-generating device with sealed compartment
US20180199617A1 (en) 2017-01-18 2018-07-19 Bianca Iodice Tobacco Free Hookah Smoking Gel
US20180199618A1 (en) 2016-09-27 2018-07-19 Bond Street Manufacturing Llc Vaporizable Tobacco Wax Compositions and Container thereof
WO2018215481A1 (en) 2017-05-24 2018-11-29 Philip Morris Products S.A. Heated aerosol-generating article comprising homogenised botanical material

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008069972A2 (en) 2006-12-01 2008-06-12 Aradigm Corporation Systems for effecting cessation of tobacco use
SE0800058L (sv) 2008-01-10 2009-07-11 British American Tobacco Co Tobaksprodukt för oral användning
PL2713778T5 (pl) 2011-05-31 2023-01-30 Philip Morris Products S.A. Pałeczki do zastosowania w wyrobach do palenia
US20140088044A1 (en) 2012-09-21 2014-03-27 Basil Rigas Product comprising a nicotine-containing material and an anti-cancer agent
GB201516729D0 (en) * 2015-09-22 2015-11-04 The Technology Partnership Plc Liquid nicotine formulation
KR101769817B1 (ko) 2015-10-30 2017-08-30 엘지전자 주식회사 가습청정장치
DK3379952T3 (da) 2015-11-25 2024-01-08 Reynolds Tobacco Co R Nikotinsalte, co-krystaller og salt-co-krystalkomplekser
CN108697152B (zh) * 2015-12-30 2022-01-11 下一代实验室有限责任公司 包含合成尼古丁的尼古丁替代疗法产品
KR20170118553A (ko) 2016-04-16 2017-10-25 김소진 배터리 호환이 가능한 휴대용 충전기
US12201767B2 (en) 2016-04-22 2025-01-21 Juul Labs, Inc. Aerosol devices having compartmentalized materials
BR112021010222A2 (pt) 2018-12-31 2021-08-24 Philip Morris Products S.A. Formulação de nicotina líquida compreendendo solventes imiscíveis em água

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2017046400A1 (en) 2015-09-18 2017-03-23 Philip Morris Products S.A. Liquid formulation of an electronic vapor device
WO2017118553A1 (en) 2016-01-07 2017-07-13 Philip Morris Products S.A. Aerosol-generating device with sealed compartment
US20180199618A1 (en) 2016-09-27 2018-07-19 Bond Street Manufacturing Llc Vaporizable Tobacco Wax Compositions and Container thereof
US20180199617A1 (en) 2017-01-18 2018-07-19 Bianca Iodice Tobacco Free Hookah Smoking Gel
WO2018215481A1 (en) 2017-05-24 2018-11-29 Philip Morris Products S.A. Heated aerosol-generating article comprising homogenised botanical material

Also Published As

Publication number Publication date
JP2022516859A (ja) 2022-03-03
WO2020136063A1 (en) 2020-07-02
KR20210108388A (ko) 2021-09-02
JP7551621B2 (ja) 2024-09-17
BR112021010229A2 (pt) 2021-08-24
EP3902565B1 (en) 2023-04-26
US20220053816A1 (en) 2022-02-24
EP3902565A1 (en) 2021-11-03
US12290093B2 (en) 2025-05-06
CN113164610A (zh) 2021-07-23

Similar Documents

Publication Publication Date Title
KR102877959B1 (ko) 고 점도 니코틴 제형
KR102930095B1 (ko) 수불혼화성 용매를 포함하는 액체 니코틴 제형
KR102877961B1 (ko) 저 몰 질량 금속염을 포함하는 액체 니코틴 제형
KR102877956B1 (ko) 금속염을 포함하는 니코틴 제형
US20230000131A1 (en) A formulation for use in an aerosol-generating system
US20230023830A1 (en) A formulation for use in an aerosol-generating system
RU2821713C2 (ru) Жидкая никотиновая композиция, содержащая соль металла с низкой молекулярной массой
RU2812319C2 (ru) Никотиновая композиция, содержащая соль металла
RU2804837C2 (ru) Никотиновая композиция высокой вязкости
JP6214135B2 (ja) 人体用害虫忌避エアゾール剤、及びこれを用いた害虫忌避並びに冷感の付与方法。
RU2814483C1 (ru) Состав для использования в системе, генерирующей аэрозоль

Legal Events

Date Code Title Description
PA0105 International application

St.27 status event code: A-0-1-A10-A15-nap-PA0105

PG1501 Laying open of application

St.27 status event code: A-1-1-Q10-Q12-nap-PG1501

A201 Request for examination
P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

P13-X000 Application amended

St.27 status event code: A-2-2-P10-P13-nap-X000

PA0201 Request for examination

St.27 status event code: A-1-2-D10-D11-exm-PA0201

R18-X000 Changes to party contact information recorded

St.27 status event code: A-3-3-R10-R18-oth-X000

E902 Notification of reason for refusal
PE0902 Notice of grounds for rejection

St.27 status event code: A-1-2-D10-D21-exm-PE0902

P11-X000 Amendment of application requested

St.27 status event code: A-2-2-P10-P11-nap-X000

D22 Grant of ip right intended

Free format text: ST27 STATUS EVENT CODE: A-1-2-D10-D22-EXM-PE0701 (AS PROVIDED BY THE NATIONAL OFFICE)

PE0701 Decision of registration

St.27 status event code: A-1-2-D10-D22-exm-PE0701

PR1002 Payment of registration fee

St.27 status event code: A-2-2-U10-U12-oth-PR1002

Fee payment year number: 1

U12 Designation fee paid

Free format text: ST27 STATUS EVENT CODE: A-2-2-U10-U12-OTH-PR1002 (AS PROVIDED BY THE NATIONAL OFFICE)

Year of fee payment: 1

PG1601 Publication of registration

St.27 status event code: A-4-4-Q10-Q13-nap-PG1601

Q13 Ip right document published

Free format text: ST27 STATUS EVENT CODE: A-4-4-Q10-Q13-NAP-PG1601 (AS PROVIDED BY THE NATIONAL OFFICE)