CN113164610A - 包含低摩尔质量金属盐的液体尼古丁制剂 - Google Patents

包含低摩尔质量金属盐的液体尼古丁制剂 Download PDF

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Publication number
CN113164610A
CN113164610A CN201980079078.8A CN201980079078A CN113164610A CN 113164610 A CN113164610 A CN 113164610A CN 201980079078 A CN201980079078 A CN 201980079078A CN 113164610 A CN113164610 A CN 113164610A
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CN
China
Prior art keywords
nicotine formulation
liquid nicotine
aerosol
weight
content
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201980079078.8A
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English (en)
Chinese (zh)
Inventor
I·陶里诺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Philip Morris Products SA
Original Assignee
Philip Morris Products SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philip Morris Products SA filed Critical Philip Morris Products SA
Publication of CN113164610A publication Critical patent/CN113164610A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10—Chemical features of tobacco products or tobacco substitutes
    • A24B15/16—Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/24—Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241—Extraction of specific substances
    • A24B15/243—Nicotine
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24B—MANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00—Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18—Treatment of tobacco products or tobacco substitutes
    • A24B15/28—Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32—Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/465—Nicotine; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/10—Devices using liquid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/40—Constructional details, e.g. connection of cartridges and battery parts

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Toxicology (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Manufacture Of Tobacco Products (AREA)
CN201980079078.8A 2018-12-28 2019-12-18 包含低摩尔质量金属盐的液体尼古丁制剂 Pending CN113164610A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18248177 2018-12-28
EP18248177.0 2018-12-28
PCT/EP2019/086111 WO2020136063A1 (en) 2018-12-28 2019-12-18 Liquid nicotine formulation comprising low molar mass metal salt

Publications (1)

Publication Number Publication Date
CN113164610A true CN113164610A (zh) 2021-07-23

Family

ID=65010470

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201980079078.8A Pending CN113164610A (zh) 2018-12-28 2019-12-18 包含低摩尔质量金属盐的液体尼古丁制剂

Country Status (7)

Country Link
US (1) US12290093B2 (https=)
EP (1) EP3902565B1 (https=)
JP (1) JP7551621B2 (https=)
KR (1) KR102877961B1 (https=)
CN (1) CN113164610A (https=)
BR (1) BR112021010229A2 (https=)
WO (1) WO2020136063A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117378803A (zh) * 2023-10-17 2024-01-12 东莞市吉纯生物技术有限公司 一种固体雾化油及其制备方法

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115191639A (zh) * 2021-04-12 2022-10-18 深圳市合元科技有限公司 气溶胶形成基质以及气溶胶生成系统

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180199617A1 (en) * 2017-01-18 2018-07-19 Bianca Iodice Tobacco Free Hookah Smoking Gel
US20180256560A1 (en) * 2015-09-22 2018-09-13 Ttp Plc Liquid nicotine formulation
WO2018215481A1 (en) * 2017-05-24 2018-11-29 Philip Morris Products S.A. Heated aerosol-generating article comprising homogenised botanical material

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008069972A2 (en) 2006-12-01 2008-06-12 Aradigm Corporation Systems for effecting cessation of tobacco use
SE0800058L (sv) 2008-01-10 2009-07-11 British American Tobacco Co Tobaksprodukt för oral användning
PL2713778T5 (pl) 2011-05-31 2023-01-30 Philip Morris Products S.A. Pałeczki do zastosowania w wyrobach do palenia
US20140088044A1 (en) 2012-09-21 2014-03-27 Basil Rigas Product comprising a nicotine-containing material and an anti-cancer agent
US20170079322A1 (en) 2015-09-18 2017-03-23 Altria Client Services Llc Liquid formulation of an electronic vapor device
KR101769817B1 (ko) 2015-10-30 2017-08-30 엘지전자 주식회사 가습청정장치
DK3379952T3 (da) 2015-11-25 2024-01-08 Reynolds Tobacco Co R Nikotinsalte, co-krystaller og salt-co-krystalkomplekser
CN108697152B (zh) * 2015-12-30 2022-01-11 下一代实验室有限责任公司 包含合成尼古丁的尼古丁替代疗法产品
EP3399876B2 (en) 2016-01-07 2026-03-04 Philip Morris Products S.A. Aerosol-generating device with sealed compartment
KR20170118553A (ko) 2016-04-16 2017-10-25 김소진 배터리 호환이 가능한 휴대용 충전기
US12201767B2 (en) 2016-04-22 2025-01-21 Juul Labs, Inc. Aerosol devices having compartmentalized materials
US20180199618A1 (en) 2016-09-27 2018-07-19 Bond Street Manufacturing Llc Vaporizable Tobacco Wax Compositions and Container thereof
BR112021010222A2 (pt) 2018-12-31 2021-08-24 Philip Morris Products S.A. Formulação de nicotina líquida compreendendo solventes imiscíveis em água

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180256560A1 (en) * 2015-09-22 2018-09-13 Ttp Plc Liquid nicotine formulation
US20180199617A1 (en) * 2017-01-18 2018-07-19 Bianca Iodice Tobacco Free Hookah Smoking Gel
WO2018215481A1 (en) * 2017-05-24 2018-11-29 Philip Morris Products S.A. Heated aerosol-generating article comprising homogenised botanical material

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117378803A (zh) * 2023-10-17 2024-01-12 东莞市吉纯生物技术有限公司 一种固体雾化油及其制备方法

Also Published As

Publication number Publication date
JP2022516859A (ja) 2022-03-03
WO2020136063A1 (en) 2020-07-02
KR20210108388A (ko) 2021-09-02
KR102877961B1 (ko) 2025-10-30
JP7551621B2 (ja) 2024-09-17
BR112021010229A2 (pt) 2021-08-24
EP3902565B1 (en) 2023-04-26
US20220053816A1 (en) 2022-02-24
EP3902565A1 (en) 2021-11-03
US12290093B2 (en) 2025-05-06

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