JP7542077B2 - 過剰な遊離ｌｉｇｈｔに関与する方法及び治療 - Google Patents

過剰な遊離ｌｉｇｈｔに関与する方法及び治療 Download PDF

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JP7542077B2
JP7542077B2 JP2022559844A JP2022559844A JP7542077B2 JP 7542077 B2 JP7542077 B2 JP 7542077B2 JP 2022559844 A JP2022559844 A JP 2022559844A JP 2022559844 A JP2022559844 A JP 2022559844A JP 7542077 B2 JP7542077 B2 JP 7542077B2
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JP2023520216A5 (enExample
JP2023520216A (ja
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ギャリー エー． ニール，
インバル ザフィア－ラビ，
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アヴァロ セラピューティクス， インコーポレイテッド
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    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • C—CHEMISTRY; METALLURGY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
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    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2875—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF/TNF superfamily, e.g. CD70, CD95L, CD153, CD154
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
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JP2022559844A 2020-04-01 2021-03-31 過剰な遊離ｌｉｇｈｔに関与する方法及び治療 Active JP7542077B2 (ja)

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JP2024137709A JP2024159821A (ja) 2020-04-01 2024-08-19 過剰な遊離ｌｉｇｈｔに関与する方法及び治療

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US202063003826P 2020-04-01 2020-04-01
US63/003,826 2020-04-01
US202063027127P 2020-05-19 2020-05-19
US63/027,127 2020-05-19
US202163133636P 2021-01-04 2021-01-04
US63/133,636 2021-01-04
PCT/US2021/025068 WO2021202649A2 (en) 2020-04-01 2021-03-31 Methods and treatment involving excess free light

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Citations (2)

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JP2010502183A (ja) 2006-08-28 2010-01-28 協和発酵キリン株式会社 アンタゴニストのヒトｌｉｇｈｔ特異的ヒトモノクローナル抗体
US20190315876A1 (en) 2018-01-24 2019-10-17 Capella Bioscience Ltd. Antigen Binding Molecules That Bind LIGHT

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US7118742B2 (en) 1997-07-07 2006-10-10 La Jolla Institute For Allergy And Immunology Ligand for herpes simplex virus entry mediator and methods of use
US6998108B1 (en) 1997-07-07 2006-02-14 La Jolla Institute For Allergy And Immunology Antibodies to p30 polypeptides and methods making and using same
DE60143231D1 (de) 2000-04-12 2010-11-18 Jolla Inst Allergy Immunolog Ligand des zelleintritt-vermittelnden Proteins von Herpes Simplex und Methoden zu dessen Verwendungen
WO2010006071A1 (en) 2008-07-08 2010-01-14 La Jolla Institute For Allergy And Immunology Hvem/btla, hvem/cd160 and hvem/gd cis complexes and methods of use
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SI2292663T1 (sl) * 2006-08-28 2014-02-28 Kyowa Hakko Kirin Co., Ltd Antagonistična humana monoklonska protitelesa, specifična za humani LIGHT
EP2160200B1 (en) 2007-05-14 2013-07-10 The University of Chicago Antibody-LIGHT fusion products as cancer therapeutics
US20090136427A1 (en) 2007-09-18 2009-05-28 La Jolla Institute For Allergy And Immunology LIGHT Inhibitors For Asthma, Lung and Airway Inflammation, Respiratory, Interstitial, Pulmonary and Fibrotic Disease Treatment
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WO2013148350A2 (en) 2012-03-26 2013-10-03 Sanofi Anti-light antibody therapy for inflammatory bowel disease
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US20190315876A1 (en) 2018-01-24 2019-10-17 Capella Bioscience Ltd. Antigen Binding Molecules That Bind LIGHT

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US11708406B2 (en) 2023-07-25
MX2022011811A (es) 2022-10-07
CA3173873A1 (en) 2021-10-07
WO2021202649A2 (en) 2021-10-07
KR102703936B1 (ko) 2024-09-10
WO2021202649A3 (en) 2021-11-11
TW202204405A (zh) 2022-02-01
BR112022019112A2 (pt) 2022-11-08
CN115768791B (zh) 2024-05-24
TWI865759B (zh) 2024-12-11
US20240002492A1 (en) 2024-01-04
CN118818053A (zh) 2024-10-22
KR20220161387A (ko) 2022-12-06
EP4126945A2 (en) 2023-02-08
EP4126945B1 (en) 2026-04-01
JP2023520216A (ja) 2023-05-16
US20210324066A1 (en) 2021-10-21
AU2021248833A1 (en) 2022-09-22
CN115768791A (zh) 2023-03-07
US12331107B2 (en) 2025-06-17
JP2024159821A (ja) 2024-11-08
KR20240135067A (ko) 2024-09-10
US20260085112A1 (en) 2026-03-26
EP4126945A4 (en) 2024-02-28

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