JP7531821B2 - 経皮薬物送達システムのための伸縮可能なバッキング層 - Google Patents

経皮薬物送達システムのための伸縮可能なバッキング層 Download PDF

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JP7531821B2
JP7531821B2 JP2018524728A JP2018524728A JP7531821B2 JP 7531821 B2 JP7531821 B2 JP 7531821B2 JP 2018524728 A JP2018524728 A JP 2018524728A JP 2018524728 A JP2018524728 A JP 2018524728A JP 7531821 B2 JP7531821 B2 JP 7531821B2
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occlusive
drug delivery
delivery system
transdermal drug
polymer
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JP2018537451A (ja
JP2018537451A5 (enExample
Inventor
ケイタ モリ
タキト シマ
ジュン リャオ
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ノーヴェン ファーマシューティカルズ インコーポレイテッド
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Priority to JP2022098833A priority Critical patent/JP2022137071A/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0283—Apparatus or processes for manufacturing adhesive dressings or bandages for making adhesive or cohesive tape or fabrics therefor, e.g. coating or mechanical treatments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7092—Transdermal patches having multiple drug layers or reservoirs, e.g. for obtaining a specific release pattern, or for combining different drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Manufacturing & Machinery (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2018524728A 2015-11-16 2016-11-15 経皮薬物送達システムのための伸縮可能なバッキング層 Active JP7531821B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2022098833A JP2022137071A (ja) 2015-11-16 2022-06-20 経皮薬物送達システムのための伸縮可能なバッキング層

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562255700P 2015-11-16 2015-11-16
US62/255,700 2015-11-16
PCT/US2016/061971 WO2017087354A1 (en) 2015-11-16 2016-11-15 Stretchable backing layers for transdermal drug delivery systems

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2022098833A Division JP2022137071A (ja) 2015-11-16 2022-06-20 経皮薬物送達システムのための伸縮可能なバッキング層

Publications (3)

Publication Number Publication Date
JP2018537451A JP2018537451A (ja) 2018-12-20
JP2018537451A5 JP2018537451A5 (enExample) 2019-12-26
JP7531821B2 true JP7531821B2 (ja) 2024-08-13

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JP2018524728A Active JP7531821B2 (ja) 2015-11-16 2016-11-15 経皮薬物送達システムのための伸縮可能なバッキング層
JP2022098833A Pending JP2022137071A (ja) 2015-11-16 2022-06-20 経皮薬物送達システムのための伸縮可能なバッキング層

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JP2022098833A Pending JP2022137071A (ja) 2015-11-16 2022-06-20 経皮薬物送達システムのための伸縮可能なバッキング層

Country Status (3)

Country Link
US (2) US20170136124A1 (enExample)
JP (2) JP7531821B2 (enExample)
WO (1) WO2017087354A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12429391B2 (en) * 2021-04-05 2025-09-30 Purdue Research Foundation Systems and methods for measuring tension distribution in webs of roll-to-roll processes
DE102021128912A1 (de) 2021-11-05 2023-05-11 Lts Lohmann Therapie-Systeme Ag. Okklusives pflaster mit flexibler backing
EP4338740A1 (en) 2022-09-13 2024-03-20 Johannes Gutenberg-Universität Mainz A transdermal patch for promoting or accelerating myelination and/or remyelination

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004516916A (ja) 2001-01-30 2004-06-10 エルテーエス ローマン テラピー−ジステーメ アーゲー カルボキシル基を含有する非ステロイドの抗炎症剤を投与するための経皮治療吸収システム及びその製造方法
WO2009096315A1 (ja) 2008-01-31 2009-08-06 Hisamitsu Pharmaceutical Co., Inc. 貼付剤
WO2014106009A1 (en) 2012-12-28 2014-07-03 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of non-steroidal anti-inflammatory agents
JP2014526546A (ja) 2011-09-26 2014-10-06 エルテーエス ローマン テラピー−ジステーメ アーゲー 調節可能な閉塞を有するプラスター
WO2015087927A1 (ja) 2013-12-12 2015-06-18 久光製薬株式会社 カバー材付き貼付剤及びカバー材付き貼付剤キット

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5843368B2 (ja) 1980-10-30 1983-09-27 日東電工株式会社 消炎鎮痛貼付剤
US4655767A (en) 1984-10-29 1987-04-07 Dow Corning Corporation Transdermal drug delivery devices with amine-resistant silicone adhesives
US4585836A (en) 1984-10-29 1986-04-29 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product with improved lap-shear stability-II
US4591622A (en) 1984-10-29 1986-05-27 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product thereof
US4584355A (en) 1984-10-29 1986-04-22 Dow Corning Corporation Silicone pressure-sensitive adhesive process and product with improved lap-shear stability-I
US4994267A (en) 1988-03-04 1991-02-19 Noven Pharmaceuticals, Inc. Transdermal acrylic multipolymer drug delivery system
US6337086B1 (en) 1999-02-06 2002-01-08 Dow Corning Corporation Pressure sensitive adhesive compositions for transdermal drug delivery devices
US20040258741A1 (en) * 2001-10-17 2004-12-23 Takaaki Terahara Percutaneous absorption preparations
CA2476622C (en) * 2002-02-19 2010-08-03 Hisamitsu Pharmaceutical Co., Inc. A transdermal patch
JP2009022730A (ja) * 2007-06-18 2009-02-05 Kyoritsu Yakuhin Kogyo Kk 貼付剤
KR101788802B1 (ko) * 2010-12-24 2017-10-20 주식회사 삼양바이오팜 리바스티그민을 함유하는 경피흡수제제
WO2014159573A1 (en) * 2013-03-14 2014-10-02 Noven Pharmaceuticals, Inc Methylphenidate transdermal compositions with rubber-based adhesives
JP6528154B2 (ja) * 2013-09-06 2019-06-12 日東電工株式会社 ビソプロロール含有貼付製剤

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004516916A (ja) 2001-01-30 2004-06-10 エルテーエス ローマン テラピー−ジステーメ アーゲー カルボキシル基を含有する非ステロイドの抗炎症剤を投与するための経皮治療吸収システム及びその製造方法
WO2009096315A1 (ja) 2008-01-31 2009-08-06 Hisamitsu Pharmaceutical Co., Inc. 貼付剤
JP2014526546A (ja) 2011-09-26 2014-10-06 エルテーエス ローマン テラピー−ジステーメ アーゲー 調節可能な閉塞を有するプラスター
WO2014106009A1 (en) 2012-12-28 2014-07-03 Noven Pharmaceuticals, Inc. Compositions and methods for transdermal delivery of non-steroidal anti-inflammatory agents
WO2015087927A1 (ja) 2013-12-12 2015-06-18 久光製薬株式会社 カバー材付き貼付剤及びカバー材付き貼付剤キット

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JP2018537451A (ja) 2018-12-20
WO2017087354A1 (en) 2017-05-26
JP2022137071A (ja) 2022-09-21
US20170136124A1 (en) 2017-05-18
US20220023425A1 (en) 2022-01-27

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