JP7511548B2 - Gip受容体アゴニストペプチド化合物及びその使用 - Google Patents

Gip受容体アゴニストペプチド化合物及びその使用 Download PDF

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Publication number
JP7511548B2
JP7511548B2 JP2021516719A JP2021516719A JP7511548B2 JP 7511548 B2 JP7511548 B2 JP 7511548B2 JP 2021516719 A JP2021516719 A JP 2021516719A JP 2021516719 A JP2021516719 A JP 2021516719A JP 7511548 B2 JP7511548 B2 JP 7511548B2
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group
ala
receptor agonist
ser
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JP2022500483A (ja
JP2022500483A5 (enExample
Inventor
志郎 竹河
智子 森本
穣 丸山
宏彰 永井
晃 田中
久典 松井
敦子 大日方
セシル コール,デレック
フリンスパッチ,マック
スコラ,ニック
スレシュ バート,アビジット
チャールズ オリヴィエ ヘニノット,アントワン
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Takeda Pharmaceutical Co Ltd
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Otolaryngology (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
JP2021516719A 2018-09-24 2019-09-24 Gip受容体アゴニストペプチド化合物及びその使用 Active JP7511548B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024077833A JP2024105512A (ja) 2018-09-24 2024-05-13 Gip受容体アゴニストペプチド化合物及びその使用

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862735510P 2018-09-24 2018-09-24
US62/735,510 2018-09-24
PCT/JP2019/038827 WO2020067575A1 (en) 2018-09-24 2019-09-24 Gip receptor agonist peptide compounds and uses thereof

Related Child Applications (1)

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JP2024077833A Division JP2024105512A (ja) 2018-09-24 2024-05-13 Gip受容体アゴニストペプチド化合物及びその使用

Publications (3)

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JP2022500483A JP2022500483A (ja) 2022-01-04
JP2022500483A5 JP2022500483A5 (enExample) 2022-10-03
JP7511548B2 true JP7511548B2 (ja) 2024-07-05

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JP2021516719A Active JP7511548B2 (ja) 2018-09-24 2019-09-24 Gip受容体アゴニストペプチド化合物及びその使用
JP2024077833A Pending JP2024105512A (ja) 2018-09-24 2024-05-13 Gip受容体アゴニストペプチド化合物及びその使用

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US (1) US20220016215A1 (enExample)
EP (1) EP3856339A1 (enExample)
JP (2) JP7511548B2 (enExample)
WO (1) WO2020067575A1 (enExample)

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AR119471A1 (es) 2019-08-01 2021-12-22 Lilly Co Eli Compuestos agonistas de gipr
IL296592A (en) * 2020-03-25 2022-11-01 Takeda Pharmaceuticals Co Qd dosing of gip receptor agonist peptide compounds and uses thereof
CN118754965A (zh) 2020-05-29 2024-10-11 北京拓界生物医药科技有限公司 Glp-1和gip受体双重激动剂化合物及其应用
CN116635055A (zh) * 2020-10-16 2023-08-22 韩美药品株式会社 包括gip衍生物或其长效缀合物的用于预防或治疗狼疮相关疾病的药物组合物
CN116583533A (zh) 2020-10-16 2023-08-11 韩美药品株式会社 Gip衍生物、其长效缀合物和包括其的药物组合物
KR20240118914A (ko) 2021-01-20 2024-08-05 바이킹 테라퓨틱스 인코포레이티드 대사 및 간 질환 치료를 위한 조성물 및 방법
CN117866050A (zh) * 2021-05-28 2024-04-12 广东众生睿创生物科技有限公司 多肽的制备及其应用
CA3231953A1 (en) 2021-09-15 2023-03-23 Brian Lian Compositions and methods for the treatment of metabolic and liver disorders
JP7886963B2 (ja) * 2022-04-07 2026-07-08 広東衆生睿創生物科技有限公司 糖尿病、肥満症およびその関連疾患を治療および/または予防するための医薬品の調製における、ポリペプチドの医薬的使用
CN119894921A (zh) * 2022-09-15 2025-04-25 伊莱利利公司 Gip和glp-1双重激动剂化合物
CN120349392A (zh) * 2023-11-06 2025-07-22 成都奥达生物科技有限公司 一种gip激动剂化合物
WO2025154020A1 (en) * 2024-01-19 2025-07-24 Takeda Pharmaceutical Company Limited Improved gip receptor agonist peptide compounds and uses thereof
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JP2022544061A (ja) 2019-08-01 2022-10-17 イーライ リリー アンド カンパニー Giprアゴニスト化合物

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JP2024105512A (ja) 2024-08-06
JP2022500483A (ja) 2022-01-04
EP3856339A1 (en) 2021-08-04
US20220016215A1 (en) 2022-01-20
WO2020067575A1 (en) 2020-04-02

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