JP7510170B2 - ５－［［４－［２－［５－アセチルピリジン－２－イル］エトキシ］ベンジル］－１，３－チアゾリジン－２，４－ジオンおよびその塩の使用 - Google Patents
５－［［４－［２－［５－アセチルピリジン－２－イル］エトキシ］ベンジル］－１，３－チアゾリジン－２，４－ジオンおよびその塩の使用 Download PDFInfo
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- JP7510170B2 JP7510170B2 JP2020567972A JP2020567972A JP7510170B2 JP 7510170 B2 JP7510170 B2 JP 7510170B2 JP 2020567972 A JP2020567972 A JP 2020567972A JP 2020567972 A JP2020567972 A JP 2020567972A JP 7510170 B2 JP7510170 B2 JP 7510170B2
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- thiazolidine
- ethoxy
- dione
- phenyl
- methyl
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| EP18382402 | 2018-06-06 | ||
| EP18382402.8 | 2018-06-06 | ||
| PCT/IB2019/054744 WO2019234690A1 (en) | 2018-06-06 | 2019-06-06 | Use of 5-[[4-[2-[5-acetylpyridin-2-yl]ethoxy]benzyl]-1,3-thiazolidine-2,4-dione and its salts |
Publications (4)
| Publication Number | Publication Date |
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| JP2021527061A JP2021527061A (ja) | 2021-10-11 |
| JPWO2019234690A5 JPWO2019234690A5 (https=) | 2022-06-14 |
| JP2021527061A5 JP2021527061A5 (https=) | 2022-06-14 |
| JP7510170B2 true JP7510170B2 (ja) | 2024-07-03 |
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| US20130158077A1 (en) | 2011-12-19 | 2013-06-20 | Ares Trading S.A. | Pharmaceutical compositions |
| FI3801515T3 (fi) | 2018-06-06 | 2025-05-27 | Minoryx Therapeutics S L | 5-[[4-[2-[5-(1-hydroksietyyli)pyridin-2-yyli]etoksi]fenyyli]metyyli]-1,3-tiatsolidiini-2,4-dionia ja sen suoloja käytettäviksi mitokondriosairauksien hoidossa |
| EP4142720A1 (en) * | 2020-04-30 | 2023-03-08 | Minoryx Therapeutics S.L. | Leriglitazone for treating lung inflammation and interstitial lung disease |
| CN117769418A (zh) * | 2021-05-19 | 2024-03-26 | 爱博利瓦有限公司 | Kl1333用于医疗 |
| MX2025013233A (es) * | 2023-05-09 | 2026-02-03 | Minoryx Therapeutics S L | Formas polimorficas y formulaciones de leriglitazona |
Citations (3)
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| JP2004518652A (ja) | 2000-12-18 | 2004-06-24 | スミスクライン ビーチャム パブリック リミテッド カンパニー | 新規治療 |
| JP2016513719A (ja) | 2013-03-14 | 2016-05-16 | デュートルクス・リミテッド・ライアビリティ・カンパニーＤｅｕｔｅＲｘ， ＬＬＣ | 重水素化２，４−チアゾリジンジオン及び治療方法 |
| JP2017511339A (ja) | 2014-04-02 | 2017-04-20 | ミノリックス セラピューティクス エセ．エレ． | 中枢神経系障害の処置における２，４−チアゾリジンジオン誘導体 |
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| GB0510469D0 (en) * | 2005-05-23 | 2005-06-29 | Leuven K U Res & Dev | Insulin sensitization to slow down pubertal tempo and to augment pubertal growth |
| AU2012203941A1 (en) * | 2006-06-27 | 2012-07-26 | Sandoz Ag | New method for salt preparation |
| WO2008000418A2 (en) * | 2006-06-27 | 2008-01-03 | Sandoz Ag | New method for salt preparation |
| WO2013040419A1 (en) * | 2011-09-14 | 2013-03-21 | The Trustees Of Columbia University In The City Of New York | Compositions and methods for treating hyperprolinemia-associated mental disorders |
| WO2017083739A1 (en) * | 2015-11-13 | 2017-05-18 | The Trustees Of Columbia University In The City Of New York | A method for predicting a subject's response to valproic acid therapy |
| EP3559010B1 (en) | 2016-12-23 | 2022-06-08 | Minoryx Therapeutics S.L. | Process for preparing 5-[[4-[2-[5-(1-hydroxyethyl)-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione and salts thereof |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004518652A (ja) | 2000-12-18 | 2004-06-24 | スミスクライン ビーチャム パブリック リミテッド カンパニー | 新規治療 |
| JP2016513719A (ja) | 2013-03-14 | 2016-05-16 | デュートルクス・リミテッド・ライアビリティ・カンパニーＤｅｕｔｅＲｘ， ＬＬＣ | 重水素化２，４−チアゾリジンジオン及び治療方法 |
| JP2017511339A (ja) | 2014-04-02 | 2017-04-20 | ミノリックス セラピューティクス エセ．エレ． | 中枢神経系障害の処置における２，４−チアゾリジンジオン誘導体 |
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| M. Kawaguchi-Suzuki et al.，Concentration-dependent response to pioglitazone in nonalcoholic steatohepatitis，Alimentary Pharmacology & Therapeutics，2017年，Vol.46，p.56-61，https://doi.org/10.1111/apt.14111 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3801517A1 (en) | 2021-04-14 |
| MX2020013182A (es) | 2021-02-26 |
| CN112823004A (zh) | 2021-05-18 |
| KR20210031867A (ko) | 2021-03-23 |
| CA3102584A1 (en) | 2019-12-12 |
| IL279186A (en) | 2021-01-31 |
| SG11202012095XA (en) | 2021-01-28 |
| WO2019234690A1 (en) | 2019-12-12 |
| US20240091210A1 (en) | 2024-03-21 |
| JP2021527061A (ja) | 2021-10-11 |
| BR112020024939A2 (pt) | 2021-03-09 |
| US20210228558A1 (en) | 2021-07-29 |
| AU2019283650A1 (en) | 2021-01-07 |
| CL2020003163A1 (es) | 2021-07-02 |
| EA202092954A1 (ru) | 2021-04-08 |
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