JP7502863B2 - 光線角化症を治療および/または予防する方法 - Google Patents

光線角化症を治療および/または予防する方法 Download PDF

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JP7502863B2
JP7502863B2 JP2019549396A JP2019549396A JP7502863B2 JP 7502863 B2 JP7502863 B2 JP 7502863B2 JP 2019549396 A JP2019549396 A JP 2019549396A JP 2019549396 A JP2019549396 A JP 2019549396A JP 7502863 B2 JP7502863 B2 JP 7502863B2
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ミン-ファン ルドルフ クワン
ジョンソン ユ-ナム ラウ
イー. ダグラス クレイマー
デビッド ローレンス カトラー
ジェーン ファン
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エイティーエヌエックス エスピーブイ リミテッド ライアビリティ カンパニー
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53771,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2019549396A 2017-03-10 2018-03-12 光線角化症を治療および/または予防する方法 Active JP7502863B2 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2022180723A JP2023015269A (ja) 2017-03-10 2022-11-11 光線角化症を治療および/または予防する方法
JP2024207319A JP2025029010A (ja) 2017-03-10 2024-11-28 光線角化症を治療および/または予防する方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762469889P 2017-03-10 2017-03-10
US62/469,889 2017-03-10
PCT/US2018/021929 WO2018165647A1 (en) 2017-03-10 2018-03-12 Methods of treating and/or preventing actinic keratosis

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JP2022180723A Division JP2023015269A (ja) 2017-03-10 2022-11-11 光線角化症を治療および/または予防する方法

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JP2020510042A JP2020510042A (ja) 2020-04-02
JP2020510042A5 JP2020510042A5 (enExample) 2021-04-08
JP7502863B2 true JP7502863B2 (ja) 2024-06-19

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JP2019549396A Active JP7502863B2 (ja) 2017-03-10 2018-03-12 光線角化症を治療および/または予防する方法
JP2022180723A Pending JP2023015269A (ja) 2017-03-10 2022-11-11 光線角化症を治療および/または予防する方法
JP2024207319A Pending JP2025029010A (ja) 2017-03-10 2024-11-28 光線角化症を治療および/または予防する方法

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JP2022180723A Pending JP2023015269A (ja) 2017-03-10 2022-11-11 光線角化症を治療および/または予防する方法
JP2024207319A Pending JP2025029010A (ja) 2017-03-10 2024-11-28 光線角化症を治療および/または予防する方法

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US (3) US10617693B2 (enExample)
EP (2) EP4659740A2 (enExample)
JP (3) JP7502863B2 (enExample)
KR (2) KR20190141661A (enExample)
CN (1) CN110891575A (enExample)
AU (2) AU2018231144B2 (enExample)
BR (1) BR112019018687A2 (enExample)
CA (1) CA3055938A1 (enExample)
IL (1) IL269182B2 (enExample)
MX (2) MX387658B (enExample)
TW (1) TWI841523B (enExample)
WO (1) WO2018165647A1 (enExample)
ZA (1) ZA202100106B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7968574B2 (en) * 2004-12-28 2011-06-28 Kinex Pharmaceuticals, Llc Biaryl compositions and methods for modulating a kinase cascade
TWI841523B (zh) * 2017-03-10 2024-05-11 美商Atnx特殊目的實體公司 治療及/或預防光化性角化症之方法
SG11202001868RA (en) 2017-09-07 2020-03-30 Athenex Hk Innovative Ltd Solid forms of 2-(5-(4-(2-morpholinoethoxy)phenyl)pyridin-2-yl)-n-benzylacetamide
US11752156B2 (en) * 2018-03-07 2023-09-12 Athenex HK Innovative Limited Compositions and methods for treating hyperproliferative skin disorders
WO2019188918A1 (ja) * 2018-03-28 2019-10-03 テルモ株式会社 医療デバイスおよび処置用法
US20220305021A1 (en) * 2019-06-05 2022-09-29 Athenex, Inc. Methods of treating and/or preventing psoriasis
EP4263833A1 (en) * 2021-01-21 2023-10-25 Sirnaomics, Inc. Compositions and methods for treatment of skin cancers
WO2025077886A1 (zh) * 2023-10-13 2025-04-17 恩康药业科技(广州)有限公司 治疗和/或预防日光性角化病的化合物及方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103274961B (zh) 2004-12-28 2016-05-18 阿西纳斯公司 治疗细胞增殖紊乱的化合物和方法
US7968574B2 (en) 2004-12-28 2011-06-28 Kinex Pharmaceuticals, Llc Biaryl compositions and methods for modulating a kinase cascade
CA2656564C (en) 2006-06-29 2015-06-16 Kinex Pharmaceuticals, Llc Biaryl compositions and methods for modulating a kinase cascade
US7538252B2 (en) 2006-09-05 2009-05-26 Bipar Sciences, Inc. Drug design for tubulin inhibitors, compositions, and methods of treatment thereof
US7935697B2 (en) 2006-12-28 2011-05-03 Kinex Pharmaceuticals, Llc Compositions for modulating a kinase cascade and methods of use thereof
TWI457336B (zh) 2006-12-28 2014-10-21 Kinex Pharmaceuticals Llc 調節激酶級聯之組成物及方法
US7939529B2 (en) 2007-05-17 2011-05-10 Kinex Pharmaceuticals, Llc Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
CA2686267C (en) 2007-05-17 2015-10-06 Kinex Pharmaceuticals, Llc Process for the preparation of compositions for modulating a kinase cascade and methods of use thereof
EP2143421A1 (en) 2008-07-07 2010-01-13 Almirall Hermal GmbH Topical composition for the treatment of actinic keratosis
DK2378876T3 (en) * 2008-12-19 2019-03-11 Medicis Pharmaceutical Corp IMIQUIMOD FORMULATIONS WITH LOWER DOSAGE STRENGTH AND SHORT-TERM DOSAGE PLAN FOR TREATMENT OF ACTINIC KERATOSIS
US8741857B1 (en) 2012-01-30 2014-06-03 Lawrence Moy Treatments for actinic keratoses
NZ606177A (en) 2012-01-30 2014-03-28 Dolorgiet Gmbh & Co Kg Compositions for the treatment of actinic keratosis
MX367055B (es) 2012-06-26 2019-08-02 Del Mar Pharmaceuticals El uso de una composición que comprende dianhidrogalactitol, diacetildianhidrogalactitol, y dibromodulcitol, y análogos o derivados de cada uno para el tratamiento de malignidades resistentes a inhibidores de tirosina cinasa.
TWI841523B (zh) * 2017-03-10 2024-05-11 美商Atnx特殊目的實體公司 治療及/或預防光化性角化症之方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
「新医薬品の臨床評価に関する一般指針について」(薬新薬第43号)各都道府県衛生主管部長宛厚生省薬務,1992年06月29日
NCT02337205,ClinicalTrials.gov,2016年,p.1-4
NCT02838628,ClinicalTrials.gov,2016年,p.1-5

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Publication number Publication date
EP4659740A2 (en) 2025-12-10
JP2020510042A (ja) 2020-04-02
EP3592355B1 (en) 2025-12-10
TW201842913A (zh) 2018-12-16
US20180256589A1 (en) 2018-09-13
AU2018231144A1 (en) 2019-10-03
KR20190141661A (ko) 2019-12-24
ZA202100106B (en) 2022-08-31
EP3592355A1 (en) 2020-01-15
KR20240090837A (ko) 2024-06-21
IL269182B1 (en) 2023-07-01
WO2018165647A1 (en) 2018-09-13
US11497750B2 (en) 2022-11-15
JP2025029010A (ja) 2025-03-05
AU2024201828A1 (en) 2024-05-02
IL269182B2 (en) 2023-11-01
BR112019018687A2 (pt) 2020-04-07
US20230172942A1 (en) 2023-06-08
MX2021013354A (es) 2021-11-18
US20200197405A1 (en) 2020-06-25
CN110891575A (zh) 2020-03-17
JP2023015269A (ja) 2023-01-31
TWI841523B (zh) 2024-05-11
CA3055938A1 (en) 2018-09-13
RU2019131757A (ru) 2021-04-12
IL269182A (en) 2019-11-28
AU2018231144B2 (en) 2023-12-21
MX387658B (es) 2025-03-18
US10617693B2 (en) 2020-04-14
RU2019131757A3 (enExample) 2021-05-31
MX2019010707A (es) 2020-01-15
EP3592355A4 (en) 2021-01-06

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